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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
24 Results for "
NAPS
" in MedChemExpress (MCE) Product Catalog:
Products (24)
24 Results for "NAPS" in MCE Product Catalog:
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1 Cited Publications
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PROTAC Bcl2 degrader-1 (Compound C5) is a PROTAC based on Cereblon ligand, which potently and selectively induces the degradation of Bcl-2 (IC50, 4.94 μM; DC50, 3.0 μM) and Mcl-1 (IC50, 11.81 μM) by introducing the E3 ligase cereblon (CRBN)-binding ligand pomalidomide to Mcl-1/Bcl-2 dual inhibitor Nap-1 .
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MCL-1/BCL-2-IN-2 (Compound Nap-1) is a potent and selective Mcl-1 and Bcl-2 dual inhibitor with IC50s of 4.45 and 3.18 μM, respectively .
Cat. No.: HY-W007648
CAS No.: 3196-73-4
Synonyms: β-Alanine methyl ester hydrochloride
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Methyl 3-aminopropanoate hydrochloride (β-Alanine methyl ester hydrochloride) is a β-alanine derivative with antioxidant activity. Methyl 3-aminopropanoate hydrochloride reduces oxidation-related changes in Glycine max soybean oil and degummed Glycine max soybean oil at frying temperatures, including the loss of olefinic protons and bis-allylic protons as well as the formation of polymerized triglycerides. Methyl 3-aminopropanoate hydrochloride contributes to the synthesis of the Bcl-2 inhibitor probe Nap-4 .
Cat. No.: HY-171631
CAS No.: 2133842-85-8
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5'-O-DMTr-Nap-dU-3'-CE Phosphoramidite is a phosphoramidite monomer used in nucleic acid synthesis, such as oligonucleotides.
Cat. No.: HY-W016791
CAS No.: 22767-49-3
Synonyms: Sodium pentane-1-sulfonate, 98%; NAPS, 98%
Cat. No.: HY-164263
CAS No.: 21830-28-4
Synonyms: NAPS
N-Acetylphytosphingosine (NAPS) is a sphingolipid derivative. N-Acetylphytosphingosine induces mitochondria-dependent Apoptosis by activating Bak. N-Acetylphytosphingosine has antitumor activity .
Cat. No.: HY-157429
CAS No.: 2865185-31-3
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25N-N1-Nap (compound 16) is a β-arrestin-biased 5-HT2A agonist. 25N-N1-Nap antagonizes phencyclidine induced hyperactivity in Male C57BL/6 J mice .
Cat. No.: HY-P10712
CAS No.: 1242159-03-0
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Cat. No.: HY-W020576
CAS No.: 139306-10-8
Synonyms: NAP 226-90
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Rivastigmine metabolite (NAP 226-90) is a metabolite produced by the hydrolysis of Rivastigmine (HY-17368) . Rivastigmine metabolite serves as a surrogate marker to track the bioavailability, metabolic extent, and transdermal patch delivery rate of Rivastigmine .
Cat. No.: HY-75423
CAS No.: 89488-30-2
Cat. No.: HY-156061
CAS No.: 131721-28-3
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NAP-1 is a compound with agent that can suppress or relieve pain. effects. NAP-1 enhances the inhibitory current by binding to a specific site of GABAaR, resulting in a narcotic effect. NAP-1 can be used in research to develop clinical agent that can suppress or relieve pain .
Cat. No.: HY-161457
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(Gly0.8Nap0.2)20 is a compound that dual targets fungal membranes and DNA. (Gly0.8Nap0.2)20 has antibacterial activity .
Cat. No.: HY-164502
CAS No.: 864516-77-8
NAP1051 is a biomimetic analog of lipin A4 that achieves anti-tumor effects by targeting the inflammatory tumor microenvironment. NAP1051 inhibits neutrophil chemotaxis to fMLP and stimulates macrophage efferocytosis by activating AKT. NAP1051 can be used in colorectal cancer research .
Cat. No.: HY-RS09026
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NAP1L1 Human Pre-designed siRNA Set A contains three designed siRNAs for NAP1L1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS09027
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NAP1L3 Human Pre-designed siRNA Set A contains three designed siRNAs for NAP1L3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS21892
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Nap1l1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Nap1l1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-101993
CAS No.: 946568-62-3
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Nap-FF is a cell-penetrating dipeptide that can be used in the preparation of hydrogel chemosensors and in the research of targeted drug delivery .
Cat. No.: HY-D1267
CAS No.: 1613402-20-2
PAO-Nap is the modified PAO attached a naphthalimide fluorophore using aminocaproic acid as a linker. PAO induces oxidative stress-mediated apoptosis in HL-60 cells by selectively targeting thioredoxin reductase .
Cat. No.: HY-144610
CAS No.: 1124167-61-8
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Mu opioid receptor antagonist 5 (compound NAP) is a selective and blood-brain barrier (BBB) penetrant μ opioid receptor (MOR) antagonist with an EC50 value of 1.14 nM and a Ki value of 0.37 nM. Mu opioid receptor antagonist 5 can be used for researching opioid use disorders (OUD) .
Cat. No.: HY-W020576R
CAS No.: 139306-10-8
Synonyms: NAP 226-90 (Standard)
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Rivastigmine metabolite (Standard) is the analytical standard of Rivastigmine metabolite. This product is intended for research and analytical applications. Rivastigmine metabolite (NAP 226-90) is a metabolite produced by the hydrolysis of Rivastigmine (HY-17368) . Rivastigmine metabolite serves as a surrogate marker to track the bioavailability, metabolic extent, and transdermal patch delivery rate of Rivastigmine .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
