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Results for "

NBS1

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (2) ATM/ATR (2) Small Interfering RNA (siRNA) (4)
By Research Areas:	Cancer (3)
Oligonucleotides:	Rat Pre-designed siRNA Sets (1) Mouse Pre-designed siRNA Sets (1) Human Pre-designed siRNA Sets (2) siRNAs (4)

Inhibitors & Agonists

Recombinant Proteins

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-19959

Mirin 5+ Cited Publications	ATM/ATR Apoptosis	Cancer
Mirin is a potent Mre11-Rad50-Nbs1 (MRN) complex inhibitor. Mirin prevents MRN-dependent activation of ATM (IC₅₀=12 μM) without affecting ATM protein kinase activity, and it inhibits Mre11-associated exonuclease activity. Mirin abolishes the G2/M checkpoint and homology-dependent repair in mammalian cells. Mirin prevents ATM activation in response to DNA double-strand breaks (DSBs) and blocks homology-directed repair (HDR) in mammalian cells ^[1] .

HY-117693

(E/Z)-Mirin 5+ Cited Publications	ATM/ATR	Cancer
(E/Z)-Mirin is a mixture of (E)-Mirin and Mirin ((Z)-Mirin) (HY-19959) configurations. Among them, Mirin is an inhibitor of MRN (Mre11-Rad50-Nbs1). Mirin prevents MRN-dependent ATM activation without affecting ATM protein kinase activity ^[1] .

HY-RS18740

Nbn Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Nbn Mouse Pre-designed siRNA Set A contains three designed siRNAs for Nbn gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Nbn Mouse Pre-designed siRNA Set A Nbn Mouse Pre-designed siRNA Set A

HY-RS09356

NLRP2 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
NLRP2 Human Pre-designed siRNA Set A contains three designed siRNAs for NLRP2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

NLRP2 Human Pre-designed siRNA Set A NLRP2 Human Pre-designed siRNA Set A

HY-RS09057

NBN Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
NBN Human Pre-designed siRNA Set A contains three designed siRNAs for NBN gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

NBN Human Pre-designed siRNA Set A NBN Human Pre-designed siRNA Set A

HY-149972

Antitumor agent-96	Apoptosis	Cancer
Antitumor agent-96 (Compound D34) is a potent MRE11 inhibitor. Antitumor agent-96 down-regulates the HR pathway by binding with MRE11 and suppressing its endonuclease functions. Antitumor agent-96 induces CM cells apoptosis ^[1].

HY-RS25227

Nbn Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Nbn Rat Pre-designed siRNA Set A contains three designed siRNAs for Nbn gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Nbn Rat Pre-designed siRNA Set A Nbn Rat Pre-designed siRNA Set A

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P703337

	NLRP2 Protein, Human (sf9) NALP2; NBS1; PAN1; PYPAF2	Human	Sf9 insect cells
	NLRP2 Protein, Human (sf9) is the recombinant human-derived NLRP2, expressed by sf9 insect cells , with tag Free labeled tag. ,

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Host:	Rabbit (4)
Reactivity:	Human (4) Mouse (1)
Application:	IHC-P (1) ICC/IF (4) IP (4) WB (4)
Isotype:	IgG (4)
Conjugation:	Non-conjugated (4)
Clonality:	Monoclonal (3) Recombinant (3)
Modification:	Phosphorylated (2) Unmodified (1)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P81775

	*p95/NBS1* Antibody (YA1520)** NBN; NBS; NBS1; P95; Nibrin; Cell cycle regulatory protein p95; Nijmegen breakage syndrome protein 1	WB, ICC/IF, IP	Human
	p95/NBS1 Antibody (YA1520) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to p95/NBS1.

HY-P81775A

	*p95/NBS1* Antibody (YA1520)(PBS only)** NBN; NBS; NBS1; P95; Nibrin; Cell cycle regulatory protein p95; Nijmegen breakage syndrome protein 1	WB, ICC/IF, IP	Human
	p95/NBS1 Antibody (YA1520) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to p95/NBS1.

HY-P83358

	*Phospho-p95/NBS1* (Ser343) Antibody (YA3103)** NBN; NBS; NBS1; P95; Nibrin; Cell cycle regulatory protein p95; Nijmegen breakage syndrome protein 1	WB, ICC/IF, IP	Human
	Phospho-p95/NBS1 (Ser343) Antibody (YA3103) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-p95/NBS1 (Ser343).

HY-P80473

	*Phospho-p95/NBS1* (Ser343) Antibody (YA165)**	WB, ICC/IF, IHC-P, IP	Human, Mouse
	Phospho-p95/NBS1 (Ser343) Antibody (YA165) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-p95/NBS1 (Ser343).

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Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Cat. No.	Product Name		Classification

HY-RS18740

Nbn Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Nbn Mouse Pre-designed siRNA Set A contains three designed siRNAs for Nbn gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS09356

NLRP2 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
NLRP2 Human Pre-designed siRNA Set A contains three designed siRNAs for NLRP2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS09057

NBN Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
NBN Human Pre-designed siRNA Set A contains three designed siRNAs for NBN gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS25227

Nbn Rat Pre-designed siRNA Set A		siRNAs Rat Pre-designed siRNA Sets
Nbn Rat Pre-designed siRNA Set A contains three designed siRNAs for Nbn gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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