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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
11 Results for "
NF-1
" in MedChemExpress (MCE) Product Catalog:
Products (11)
11 Results for "NF-1" in MCE Product Catalog:
Target:
Research Areas:
NST-628 is a brain-permeable MAPK pathway molecule glue that inhibits RAF phosphorylation and MEK activation. NST-628 also binds RAF and prevents the formation of BRAF-CRAF and BRAF-ARAF heterodimers, effectively inhibiting the RAS-MAPK pathway. NST-628 inhibits RAS- and RAF-driven cancers and demonstrated potent inhibition in mutant KRAS, NRAS, BRAF class II/III, and NF1-mutant tumors [1].
Cat. No.: HY-W273690
CAS No.: 1028-33-7
Synonyms: 1-Hexyltheobromine; Hexyltheobromine
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Research Areas:
Pentifylline (1-Hexyltheobromine; Hexyltheobromine), PTX (HY-B0715) precursor compound, is a vasodilator. Pentifylline decreases procollagen levels and inhibits collagen production. Pentifylline reduces functional nuclear NF-1 to suppress procollagen gene transcription [1] .
Cat. No.: HY-RS17398
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Research Areas:
Nf1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Nf1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS09233
Target:
Research Areas:
NF1 Human Pre-designed siRNA Set A contains three designed siRNAs for NF1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS23853
Target:
Research Areas:
Nf1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Nf1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-156872
CAS No.: 1952236-19-9
MTX-216 is a dual ATP-competitive inhibitor of PI3K and EGFR. MTX-216 cosuppresses Ki-67 and ribosomal S6 phosphorylation and induces apoptosis in NF1 LOF cells. MTX-216 suppresses the activity of SYK kinase, with an IC50 of 281 nM. MTX-216 is used in the research of Melanoma [1].
Cat. No.: HY-P85511
Synonyms: 1110019L22Rik; 1500041O16Rik; AA589446; AI746521; CAAT box transcription factor; CCAAT binding transcription factor; CCAAT box binding transcription factor; CCAAT-box-binding transcription factor; CNFI C; CTF; CTF5; MGC137374; MGC20153; NF I; NF I/C; NF-I/C; NF1 C; NF1-C; NF1C; NFI; NFI-C; NFI/C; NFIC; NFIC_HUMAN; Nuclear factor 1; Nuclear factor 1 C type; Nuclear factor 1 C-type; Nuclear factor 1/C; Nuclear factor I/C; TGGCA binding protein; TGGCA-binding protein; Transcription factor NFIC.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
