1028-33-7
1028-33-7
Chemical Structure
Pentifylline
Synonym(s): 1-Hexyltheobromine; Hexyltheobromine
- CAS No.: 1028-33-7
- Formula:C13H20N4O2
- Molecular Weight:264.32
IUPAC Name: 1-hexyl-3,7-dimethyl-3,7-dihydro-1H-purine-2,6-dione
InChIKey: MRWQRJMESRRJJB-UHFFFAOYSA-N
SMILES: CCCCCCN1C(=O)C2=C(N=CN2C)N(C)C1=O
Biological Activity: Pentifylline (1-Hexyltheobromine; Hexyltheobromine), PTX (HY-B0715) precursor compound, is a vasodilator. Pentifylline decreases procollagen levels and inhibits collagen production. Pentifylline reduces functional nuclear NF-1 to suppress procollagen gene transcription[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Pentifylline | 99.23% | Pentifylline (1-Hexyltheobromine; Hexyltheobromine), PTX (HY-B0715) precursor compound, is a vasodilator. Pentifylline decreases procollagen levels and inhibits collagen production. Pentifylline reduces functional nuclear NF-1 to suppress procollagen gene transcription. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. Aviado D M, et al. Pentoxifylline: a new drug for the treatment of intermittent claudication; mechanism of action, pharmacokinetics, clinical efficacy and adverse effects[J]. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 1984, 4(6): 297-306. [Content Brief]
- [2]. Duncan MR, et al. Pentoxifylline, pentifylline, and interferons decrease type I and III procollagen mRNA levels in dermal fibroblasts: evidence for mediation by nuclear factor 1 down-regulation. J Invest Dermatol. 1995;104(2):282-286. [Content Brief]
Keywords
