1 Result for "

NSC658497

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "NSC658497" in MCE Product Catalog:

Cat. No.: HY-19539
CAS No.: 909197-38-2
Target:  

SOS1 Ras

Domaines de recherche:  

Cancer

NSC-658497 is an effective inhibitor of Ras-GEF, SOS1. NSC-658497 binds to SOS1, competitively suppresses SOS1-Ras interaction, and dose-dependently inhibits SOS1 GEF activity. NSC-658497 showed dose-dependent efficacy in inhibiting Ras, downstream signaling activities, and associated cell proliferation .
loading...
    loading...