29 Results for "

P 15

" in MedChemExpress (MCE) Product Catalog:
Products (29)

29 Results for "P 15" in MCE Product Catalog:

21
21 Cited Publications
Cat. No.: HY-108496
CAS No.: 26993-30-6
Purity:  ≥99.0%
Synonyms: S1P
Sphingosine-1-phosphate (S1P) is an agonist of S1P1-5 receptors and a ligand of GPR3, GPR6 and GPR12. Sphingosine-1-phosphate is an intracellular second messenger and mobilizes Ca 2+ as an extracellular ligand for G protein-coupled receptors . Sphingosine-1-phosphate is an important lipid mediator generated from Sphingomyelin (HY-113498) or other membrane phospholipids . Sphingosine-1-phosphate stimulates the DNA synthesis, cell proliferation and migration .
loading...
    loading...
Cat. No.: HY-P11087
CAS No.: 134335-45-8
Target:  

Collagen RUNX Integrin

Research Areas:  

Inflammation/Immunology

P15 is a type I collagen-mimetic peptide with pro-adhesive properties. P15 binds to membrane integrin, including α2β1, to mediate cell adhesion and trigger the production of growth factors and cytokines. P15 upregulates the expression of osteogenic genes via targets including RUNX2, OSTRX and BSP. P15 stimulates the adhesion and proliferation of osteoblasts, enhances alkaline phosphatase activity and calcium deposition, and supports osteogenic differentiation. P15 can be used in research related to periodontal bone defects, cervical intervertebral disc defects, and non-union/bone defects .
loading...
    loading...
Cat. No.: HY-P3333
CAS No.: 153049-05-9
Target:  

MHC

Research Areas:  

Inflammation/Immunology Cancer

KSPWFTTL is an immunodominant Kb-restricted epitope from the p15E transmembrane protein. KSPWFTTL can restore susceptibility of a tumor line to anti-AKR/Gross MuLV cytotoxic T lymphocytes .
loading...
    loading...
Cat. No.: HY-108496S
CAS No.: 2260670-15-1
Purity:  99.00%
Synonyms: S1P-d7
Sphingosine-1-phosphate-d7 is the deuterium labeled Sphingosine-1-phosphate. Sphingosine-1-phosphate (S1P) is an agonist of S1P1-5 receptors and a ligand of GPR3, GPR6 and GPR12.?Sphingosine-1-phosphate is an intracellular second messenger and mobilizes Ca2+ as an extracellular ligand for G protein-coupled receptors . Sphingosine-1-phosphate is an important lipid mediator generated from Sphingomyelin (HY-113498) or other membrane phospholipids .
loading...
    loading...
Cat. No.: HY-P4056A
Synonyms: P15-Tat acetate
Target:  

Casein Kinase Apoptosis

Research Areas:  

Cancer

CIGB-300 acetate (P15-Tat acetate) is an anti-casein kinase 2 (CK2) peptide that exhibits anticancer properties by interfering with the phosphorylation of protein kinase CK2. CIGB-300 acetate induces apoptosis in multiple tumor cell lines and can be used in cancer research .
loading...
    loading...
Cat. No.: HY-P10365
Research Areas:  

Others

Vmm-p15 is a peptide agonist optimized for the adhesion G protein-coupled receptor GPR64 (also known as ADGRG2 or HE6). The affinity of VPM-p15 with GPR64 is significantly higher than that of the original p15 peptide. The cAMP level induced by VMM-P15 increased significantly, activated GPR64, and triggered downstream Gs, Gq, and G12/13 signaling. VPM-p15 can be used to study the activation mechanism of adherent GPCR family members .
loading...
    loading...
Cat. No.: HY-P4056
CAS No.: 1072877-99-6
Synonyms: P15-Tat
Target:  

Casein Kinase Apoptosis

Research Areas:  

Cancer

CIGB-300 (P15-Tat) is an anti-casein kinase 2 (CK2) peptide that exhibits anticancer properties by interfering with the phosphorylation of protein kinase CK2. CIGB-300 induces apoptosis in multiple tumor cell lines and can be used in cancer research .
loading...
    loading...
Cat. No.: HY-RS16621
Research Areas:  

Others

Fabp4 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Fabp4 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

loading...
    loading...
Cat. No.: HY-P3333A
Target:  

MHC

Research Areas:  

Inflammation/Immunology Cancer

KSPWFTTL TFA is an immunodominant Kb-restricted epitope from the p15E transmembrane protein. KSPWFTTL TFA can restore susceptibility of a tumor line to anti-AKR/Gross MuLV cytotoxic T lymphocytes .
loading...
    loading...
Cat. No.: HY-179909
CAS No.: 871701-39-2
Target:  

MEK CDK

Research Areas:  

Cancer

MEK-IN-9 (Compound 4-82) is a MEK inhibitor. MEK-IN-9 induces p15 and p27 protein. MEK-IN-9 can be used in the research of renal adenocarcinoma and colorectal cancer .
loading...
    loading...
Cat. No.: HY-126048
CAS No.: 871696-49-0
Target:  

MEK

Research Areas:  

Cancer

JTP-70902, a p15 INK4b-inductive compound, is a MEK1/2 inhibitor. JTP-70902 exhibits potent antitumor effect .
loading...
    loading...
Cat. No.: HY-170970
Target:  

Bacterial

Research Areas:  

Infection

Mtb-IN-10 (Compound P15) is a Rv1625c/Cya activator that regulates cAMP metabolism to influence the growth of Mycobacterium tuberculosis (Mtb). Mtb-IN-10 exhibits an EC50 of 1.96 µM in an Mtb-infected macrophage model and demonstrates 58.0% oral bioavailability in mice at a 20 mg/kg dose. It may regulate intracellular signaling and disrupt cholesterol metabolism in Mtb, thereby inhibiting bacterial proliferation. Mtb-IN-10 holds potential for tuberculosis (TB) research, particularly for combating multidrug-resistant (MDR-TB) and extensively drug-resistant (XDR-TB) Mtb strains .
loading...
    loading...
Cat. No.: HY-RS27622
Research Areas:  

Others

Cdkn2b Rat Pre-designed siRNA Set A contains three designed siRNAs for Cdkn2b gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
loading...
    loading...
Cat. No.: HY-RS09720
Research Areas:  

Others

NXT1 Human Pre-designed siRNA Set A contains three designed siRNAs for NXT1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

loading...
    loading...
Cat. No.: HY-RS13999
Research Areas:  

Others

SUB1 Human Pre-designed siRNA Set A contains three designed siRNAs for SUB1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

loading...
    loading...
Cat. No.: HY-RS02416
Research Areas:  

Others

CDKN2B Human Pre-designed siRNA Set A contains three designed siRNAs for CDKN2B gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

loading...
    loading...
Cat. No.: HY-14433A
CAS No.: 1149727-65-0
Synonyms: (S)-PF-991
Target:  

LPL Receptor

Research Areas:  

Inflammation/Immunology

(S)-PF-462991 is a direct-acting S1P1,5 agonist .
loading...
    loading...
Cat. No.: HY-164308
CAS No.: 852846-00-5
Target:  

LAG-3

Research Areas:  

Inflammation/Immunology

SA-15-P inhibits LAG-3/MHCII and LAG-3/FGL1 interactions with IC50 values of 4.21 and 6.52 μM respectively. LAG-3/MHCII interaction is a target for immunotherapies .
loading...
    loading...
Cat. No.: HY-P85850

Host:  

Mouse

Application:  

WB, ICC/IF, ELISA

Reactivity:  

Human

loading...
    loading...
Cat. No.: HY-P701328
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: BH3-interacting domain death agonist; BID; p15 BID
Species:  
Source:  
loading...
    loading...