KSPWFTTL
Based on 1 Customer Validation
KSPWFTTL is an immunodominant Kb-restricted epitope from the p15E transmembrane protein. KSPWFTTL can restore susceptibility of a tumor line to anti-AKR/Gross MuLV cytotoxic T lymphocytes.
For research use only. We do not sell to patients.
- Purity: 99.60%
- CAS No.: 153049-05-9
- Formula: C48H70N10O12
- Molecular Weight:979.13
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
KSPWFTTL is derived from the retroviral p15 TM envelope protein. The cytolytic T-lymphocyte (CTL)-insusceptible, variant cl.18-5 clonal line, after pulsed with the KSPWFTTL peptide, becomes susceptible to lysis by antiviral CTL[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 153049-05-9
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Appearance Solid
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Molecular Weight 979.13
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Formula C48H70N10O12
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Color White to off-white
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Sequence
Lys-Ser-Pro-Trp-Phe-Thr-Thr-Leu
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Sequence Shortening
KSPWFTTL
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
H2O : 100 mg/mL (102.13 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (278 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. White HD, et, al. An immunodominant Kb-restricted peptide from the p15E transmembrane protein of endogenous ecotropic murine leukemia virus (MuLV) AKR623 that restores susceptibility of a tumor line to anti-AKR/Gross MuLV cytotoxic T lymphocytes. J Virol. 1994 Feb;68(2):897-904. [Content Brief]
[2]. Rich RF, et, al. Antiretroviral cytolytic T-lymphocyte nonresponsiveness: FasL/Fas-mediated inhibition of CD4(+) and CD8(+) antiviral T cells by viral antigen-positive veto cells. J Virol. 1999 May;73(5):3826-34. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 1.0213 mL | 5.1066 mL | 10.2131 mL | 25.5329 mL |
| 5 mM | 0.2043 mL | 1.0213 mL | 2.0426 mL | 5.1066 mL | |
| 10 mM | 0.1021 mL | 0.5107 mL | 1.0213 mL | 2.5533 mL | |
| 15 mM | 0.0681 mL | 0.3404 mL | 0.6809 mL | 1.7022 mL | |
| 20 mM | 0.0511 mL | 0.2553 mL | 0.5107 mL | 1.2766 mL | |
| 25 mM | 0.0409 mL | 0.2043 mL | 0.4085 mL | 1.0213 mL | |
| 30 mM | 0.0340 mL | 0.1702 mL | 0.3404 mL | 0.8511 mL | |
| 40 mM | 0.0255 mL | 0.1277 mL | 0.2553 mL | 0.6383 mL | |
| 50 mM | 0.0204 mL | 0.1021 mL | 0.2043 mL | 0.5107 mL | |
| 60 mM | 0.0170 mL | 0.0851 mL | 0.1702 mL | 0.4255 mL | |
| 80 mM | 0.0128 mL | 0.0638 mL | 0.1277 mL | 0.3192 mL | |
| 100 mM | 0.0102 mL | 0.0511 mL | 0.1021 mL | 0.2553 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
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