153049-05-9
Chemical Structure
KSPWFTTL
- CAS No.: 153049-05-9
- Formula:C48H70N10O12
- Molecular Weight:979.13
InChIKey: ACAFPRSTSWTCSS-ALQLYSEESA-N
SMILES: O=C([C@H]1N(CCC1)C([C@H](CO)NC([C@@H](N)CCCCN)=O)=O)N[C@H](C(N[C@H](C(N[C@@H]([C@H](O)C)C(N[C@@H]([C@H](O)C)C(N[C@H](C(O)=O)CC(C)C)=O)=O)=O)CC2=CC=CC=C2)=O)CC3=CNC4=CC=CC=C34
Biological Activity: KSPWFTTL is an immunodominant Kb-restricted epitope from the p15E transmembrane protein. KSPWFTTL can restore susceptibility of a tumor line to anti-AKR/Gross MuLV cytotoxic T lymphocytes[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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KSPWFTTL | 99.60% | KSPWFTTL is an immunodominant Kb-restricted epitope from the p15E transmembrane protein. KSPWFTTL can restore susceptibility of a tumor line to anti-AKR/Gross MuLV cytotoxic T lymphocytes. | ||||||||||||||||||||
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- [1]. White HD, et, al. An immunodominant Kb-restricted peptide from the p15E transmembrane protein of endogenous ecotropic murine leukemia virus (MuLV) AKR623 that restores susceptibility of a tumor line to anti-AKR/Gross MuLV cytotoxic T lymphocytes. J Virol. 1994 Feb;68(2):897-904. [Content Brief]
- [2]. Rich RF, et, al. Antiretroviral cytolytic T-lymphocyte nonresponsiveness: FasL/Fas-mediated inhibition of CD4(+) and CD8(+) antiviral T cells by viral antigen-positive veto cells. J Virol. 1999 May;73(5):3826-34. [Content Brief]
Keywords