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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
11 Results for "
PD Biomarker
" in MedChemExpress (MCE) Product Catalog:
Products (11)
11 Results for "PD Biomarker" in MCE Product Catalog:
1
Category:
Alkaloids Human Gut Microbiota Metabolites Neurological Disease Other Alkaloids Endogenous metabolite Disease Research Fields Cancer
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1
1 Cited Publications
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Cat. No.: HY-P3140A
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Cat. No.: HY-P3140
CAS No.: 440645-08-9
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Cat. No.: HY-P5043
CAS No.: 2243206-99-5
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Cat. No.: HY-P5044
CAS No.: 2243206-98-4
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Cat. No.: HY-P5046
CAS No.: 332867-16-0
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Cat. No.: HY-P5041
CAS No.: 2170181-52-7
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Cat. No.: HY-113100R
CAS No.: 18233-70-0
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Cat. No.: HY-181848
DNA-PK-IN-16 is an orally active DNA-dependent protein kinase (DNA-PK) inhibitor with an IC50 of 10.2 nM. DNA-PK-IN-16 induces the upregulation of γH2A.X, a biomarker of DNA double-strand breaks. DNA-PK-IN-16 exhibits antiproliferative activity in various cancer cell lines. DNA-PK-IN-16 enhances the infiltration of CD8 + T cells in tumor tissues through synergistic action with anti-PD-L1 monoclonal antibody. DNA-PK-IN-16 is applicable for cancer research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
