5699-41-2
5699-41-2
Chemical Structure
N-Acetylputrescine
Synonym(s): NAP
- CAS No.: 5699-41-2
- Formula:C6H14N2O
- Molecular Weight:130.19
IUPAC Name: 4-(oxiran-2-yl)-2,8-bis(trifluoromethyl)quinoline
InChIKey: KLZGKIDSEJWEDW-UHFFFAOYSA-N
SMILES: CC(NCCCCN)=O
Biological Activity: N-Acetylputrescine is a polyamine metabolite that regulates cell proliferation and signal transduction mainly by participating in polyamine acetylation modification. N-Acetylputrescine may reduce the positive charge of polyamines, affect protein-nucleic acid interactions, and promote cell growth. The concentration changes of N-Acetylputrescine can help disease diagnosis (such as early screening and efficacy evaluation of lung cancer) and microbial cell wall structure research. N-Acetylputrescine can be used as a potential biomarker for the progression of squamous cell carcinoma of the lung (SCCL) and Parkinson's disease (PD)[1][2][3][4].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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N-Acetylputrescine | 99.54% | N-Acetylputrescine is a polyamine metabolite that regulates cell proliferation and signal transduction mainly by participating in polyamine acetylation modification. N-Acetylputrescine may reduce the positive charge of polyamines, affect protein-nucleic acid interactions, and promote cell growth. The concentration changes of N-Acetylputrescine can help disease diagnosis (such as early screening and efficacy evaluation of lung cancer) and microbial cell wall structure research. N-Acetylputrescine can be used as a potential biomarker for the progression of squamous cell carcinoma of the lung (SCCL) and Parkinson's disease (PD). | ||||||||||||||||||||
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N-Acetylputrescine (Standard) | 99.47% | N-Acetylputrescine (Standard) (NAP (Standard)) is the analytical standard of N-Acetylputrescine (HY-W342604). This product is intended for research and analytical applications. N-Acetylputrescine is a polyamine metabolite that regulates cell proliferation and signal transduction mainly by participating in polyamine acetylation modification. N-Acetylputrescine may reduce the positive charge of polyamines, affect protein-nucleic acid interactions, and promote cell growth. The concentration changes of N-Acetylputrescine can help disease diagnosis (such as early screening and efficacy evaluation of lung cancer) and microbial cell wall structure research. N-Acetylputrescine can be used as a potential biomarker for the progression of squamous cell carcinoma of the lung (SCCL) and Parkinson's disease (PD). | ||||||||||||||||||||
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Monoacetylcadaverine hydrochloride | 98.0% | Monoacetylcadaverine hydrochloride is a metabolite of the endogenous polyamine cadaverine. | ||||||||||||||||||||
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N-(5-Aminopentyl)acetamide (Standard) | 99.92% | N-(5-Aminopentyl)acetamide (Standard) is the analytical standard of N-(5-Aminopentyl)acetamide. This product is intended for research and analytical applications. N-(5-Aminopentyl)acetamide is the acetylated form of the polyamine cadaverine. | ||||||||||||||||||||
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N1-Acetylspermidine hydrochloride | 99.88% | N1-Acetylspermidine hydrochloride is an acetyl derivative of polyamines and a substrate for polyamine oxidase (PAO). N1-Acetylspermidine hydrochloride can promote Apoptosis in combination with Procyanidins. N1-Acetylspermidine hydrochloride has a certain cleavage efficiency at apurinic sites of DNA. N1-Acetylspermidine hydrochloride can be used in colorectal cancer research. | ||||||||||||||||||||
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N-Acetylputrescine hydrochloride (Standard) | ≥98% | N-Acetylputrescine hydrochloride (Standard) is the analytical standard for N-Acetylputrescine hydrochloride (HY-113100). This product is intended for research and analytical applications. N-Acetylputrescine hydrochloride is a polyamine metabolite that regulates cell proliferation and signal transduction mainly by participating in polyamine acetylation modification. N-Acetylputrescine hydrochloride may reduce the positive charge of polyamines, affect protein-nucleic acid interactions, and promote cell growth. The concentration changes of N-Acetylputrescine hydrochloride can help disease diagnosis (such as early screening and efficacy evaluation of lung cancer) and microbial cell wall structure research. N-Acetylputrescine hydrochloride can be used as a potential biomarker for the progression of squamous cell carcinoma of the lung (SCCL) and Parkinson's disease (PD). | ||||||||||||||||||||
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N8-Acetylspermidine dihydrochloride (Standard) | ≥98% | N8-Acetylspermidine dihydrochloride (Standard) is the analytical standard of N8-Acetylspermidine dihydrochloride. This product is intended for research and analytical applications. N8-Acetylspermidine dihydrochloride is a polyamine metabolite. N8-Acetylspermidine dihydrochloride can be oxidatively deaminated by copper amine oxidase. N8-Acetylspermidine dihydrochloride can also induce the differentiation of PC12 cells and promote neurite outgrowth. | ||||||||||||||||||||
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C4-Amide-C4-NH2 | C4-Amide-C4-NH2 is an active compound. C4-Amide-C4-NH2 can be used in a variety of biochemical studies. | |||||||||||||||||||||
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C3-Amide-C4-NH2 | C3-Amide-C4-NH2 is a potent linker. | |||||||||||||||||||||
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C2-Amide-C4-NH2 | C2-Amide-C4-NH2 is a potent linker. | |||||||||||||||||||||
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4-Acetylaminobutanal | 4-Acetylaminobutanal is an intermediate product of the urea cycle. | |||||||||||||||||||||
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N-(3-Aminopropyl)acetamide | N-(3-Aminopropyl)acetamide is the building block. N-(3-Aminopropyl)acetamide could be used for synthesis of Polyfluorosulfonamido amine, which is the material for surfactants, electronics elements, pharmaceutical- and pesticide intermediates. | |||||||||||||||||||||
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References
- [1]. Pfanzagl B, et al. N-acetylputrescine as a characteristic constituent of cyanelle peptidoglycan in glaucocystophyte algae. J Bacteriol. 1996 Dec;178(23):6994-7. [Content Brief]
- [2]. Menashe M, et al. Formulation of N-acetylputrescine and N1-acetylspermidine in cultured human lymphocytes. Biochem J. 1980 Apr 15;188(1):263-7. [Content Brief]
- [3]. Liu R, et al. Plasma N-acetylputrescine, cadaverine and 1,3-diaminopropane: potential biomarkers of lung cancer used to evaluate the efficacy of anticancer drugs. Oncotarget. 2017 Jul 17;8(51):88575-88585. [Content Brief]
- [4]. Peng K W, et al. Identification and Validation of N-Acetylputrescine in Combination With Non-Canonical Clinical Features As a Parkinson's Disease Biomarker Panel[J]. bioRxiv, 2021: 2021.07. 23.453542.
