2 Results for "

PDE8B-IN-1

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "PDE8B-IN-1" in MCE Product Catalog:

Cat. No.: HY-135711
CAS No.: 1305116-69-1
Research Areas:  

Metabolic Disease

PDE8B-IN-1 is a selective inhibitor of phosphodiesterase 8B (PDE8B) with the activity of enhancing insulin secretion. PDE8B-IN-1 showed good efficacy in high-throughput screening and optimized its ligand efficiency through rapid deconstruction. PDE8B-IN-1 showed high target selectivity and good bioavailability in preclinical development, providing a basis for exploring its potential inhibitory use .
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Cat. No.: HY-117848
CAS No.: 1305116-67-9
Research Areas:  

Metabolic Disease

PDE8B-IN-1 hydrochloride (compound 42) is a potent, selective PDE8B inhibitor with a IC50 value of 1.5 nM. PDE8B-IN-1 hydrochloride can be used in the study of diabetes .
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