1 Result for "

PVTX-321

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "PVTX-321" in MCE Product Catalog:

Cat. No.: HY-174131
CAS No.: 3026004-38-3
Target:  

Estrogen Receptor/ERR

Research Areas:  

Cancer

PVTX-321 (Compound 16a) is an orally active estrogen receptor α (ERα) degrader. PVTX-321 can potently degrade ERα (DC50=0.15 nM in MCF-7 cells) and also has inhibitory activity against mutant ERα (IC50=59 nM). PVTX-321 is promising for research of ER+/HER2- breast cancer .
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