1 Result for "

RU.521

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "RU.521" in MCE Product Catalog:

86
86 Cited Publications
Cat. No.: HY-114180
CAS No.: 2262452-06-0
Purity:  99.95%
Synonyms: RU320521
Research Areas:  

Metabolic Disease

RU.521 (RU320521) is a potent and selective cyclic GMP-AMP synthase (cGAS) inhibitor and inhibits cGAS-mediated interferon upregulation. RU.521 suppresses dsDNA-activated reporter activity with an IC50 of 0.7 μM. RU.521 reduces constitutive expression of interferon in macrophages from a mouse model of Aicardi-Goutières syndrome (AGS) .
loading...
    loading...