1 Result for "

SST0116CL1 free base

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "SST0116CL1 free base" in MCE Product Catalog:

Cat. No.: HY-164399A
CAS No.: 1202920-93-1
Target:  

HSP ERK CDK Akt

Research Areas:  

Cancer

SST0116CL1 free base is a HSP90 inhibitor (IC50: 0.21 μM). SST0116CL1 free base binds to the ATP binding pocket of Hsp90, and interferes with Hsp90 chaperone function thus resulting in client protein (EGFR, CDK4 and AKT) degradation. SST0116CL1 free base induces degradation of Her2 in BT-474 cell (IC50: 0.2 μM). SST0116CL1 free base has antiproliferative activity and inhibits tumor growth. SST0116CL1 free base has antiproliferative activity and inhibits tumor growth. SST0116CL1 free base can be used for the study of leukemia, gastric and ovarian carcinoma .
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