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Results for "

SULTs

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Cytochrome P450 (1) Drug Metabolite (2) Endogenous Metabolite (2) Environmental Pollutants (1) Fluorescent Dye (2) Interleukin Related (1) Keap1-Nrf2 (1) NF-κB (1) Pregnane X Receptor (PXR) (1) PROTACs (1) Reference Standards (1) Small Interfering RNA (siRNA) (24) SULT (2)
By Research Areas:	Cancer (1) Endocrinology (1) Infection (1) Metabolic Disease (3) Neurological Disease (2)
Click Chemistry:	Labeling and Fluorescence Imaging (1) Azide (1)
Oligonucleotides:	Rat Pre-designed siRNA Sets (7) Mouse Pre-designed siRNA Sets (7) Human Pre-designed siRNA Sets (10) siRNAs (24)

Inhibitors & Agonists

Fluorescent Dyes

Biochemical Assay Reagents

Natural
Products

Click Chemistry

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-119323

7-Azido-4-methylcoumarin 1 Publications Verification	Fluorescent Dye	Others
7-Azido-4-methylcoumarin is a selective coumarin-based fluorescent probe for hydrogen sulfide (H₂S). In the presence of H₂S, the aromatic azido group of 7-Azido-4-methylcoumarin is selectively reduced to produce the fluorescently active 7-amino-4-methylcoumarin (AMC). 7-Azido-4-methylcoumarin binds to the coumarin/phenol-binding site of BSA, the aglycone-binding site of UGT1A6, and the substrate-binding site of *SULT1A1*, respectively. 7-Azido-4-methylcoumarin retains its fluorescent properties after covalent binding, acts as a fluorescent H₂S probe, and does not react with cysteine, homocysteine or glutathione (Ex/Em = 340/445 nm) .

HY-113257

Dopamine 4-sulfate DA-4S; Dopamine 4-Sulfate	Drug Metabolite	Neurological Disease
Dopamine 4-sulfate (DA-4S) is an inactive metabolite of the catecholamine dopamine. It is formed from dopamine by the sulfotransferase (SULT) isoform SULT1A3. Dopamine 4-O-sulfate is found at lower levels in the brain and circulation than dopamine 3-O-sulfate.

HY-W012206

(Rac)-Metanephrine hydrochloride	SULT	Neurological Disease Cancer
(Rac)-Metanephrine hydrochloride is a metabolite of epinephrine and a substrate of the sulfotransferase *SULT1A3. (Rac)-Metanephrine hydrochloride undergoes sulfonation at its p-hydroxyl group via a reaction catalyzed by SULT1A3*. (Rac)-Metanephrine hydrochloride is an isomer of Metanephrine (HY-113299) hydrochloride, and it is applicable to the research of pheochromocytoma .

HY-148642

12-Hydroxynevirapine 12-hydroxy-NVP; 12-OH-NVP	Drug Metabolite	Infection
12-Hydroxynevirapine (12-hydroxy-NVP; 12-OH-NVP) is a major oxidative metabolite of Nevirapine (HY-10570). Nevirapine is a non-nucleoside reverse transcriptase inhibitor indicated for the HIV-1 infections. Nevirapine causes idiosyncratic hepatotoxicity and mild-to-severe skin rashes. 12-Hydroxynevirapine, a non-reactive metabolite, can be bioactivated by sulphotransferases (SULTs) in the liver and skin, yielding the reactive species 12-Sulphoxy-nevirapine .

HY-175266

MI1013	PROTACs Cytochrome P450 Pregnane X Receptor (PXR)	Metabolic Disease
MI1013 is a PROTAC PXR degrader (DC₅₀ = 89 nM, D_max = 82%). MI1013 degrades PXR in human hepatocellular carcinoma RG cells (HepaRG). MI1013 specifically and safely regulates CYP3A4 promoter activity through PXR degradation. MI1013 affects several key genes involved in sulfate conjugation (e.g., SULT1E1), bile acid synthesis (CYP7A1), gluconeogenesis (PCK1), ketone synthesis (HMGCS20), and hepatocyte proliferation (MKI67). (Pink: PXR ligand 3: HY-175267, Blue: Pomalidomide-propargyl ligand: HY-W410002, Pink + Black: PXR ligand-Linker Conjugate 1: HY-175268) .

HY-N1902R

4-Hydroxyphenylacetic acid (Standard)	Reference Standards Keap1-Nrf2 Endogenous Metabolite	Metabolic Disease
4-Hydroxyphenylacetic acid (Standard) is the analytical standard of 4-Hydroxyphenylacetic acid. This product is intended for research and analytical applications. 4-hydroxyphenylacetic acid, a major microbiota-derived metabolite of polyphenols, is involved in the antioxidative action. 4-hydroxyphenylacetic acid induces expression of Nrf2 . IC₅₀ & Target:Nrf2 In Vivo: 4-Hydroxyphenylacetic acid (6, 12, or 25 mg/kg) increases Nrf2 translocation to the nucleus and enhances the activity of phase II and antioxidant enzymes. The protein levels of nuclear Nrf2 are increased by 170% and 230% in pre-treated 12 and 25 mg/kg 4-Hydroxyphenylacetic acid groups, respectively, compared with the control group.The 4-Hydroxyphenylacetic acid pretreatment at a final dose of 25 mg/kg markedly and selectively up-regulated the target genes of phase II enzymes and resulted in higher up-regulation than that of the control group by 270%, 400%, and 500% or UGT1A1, UGT1A9, and SULT2A1, respectively. 4-Hydroxyphenylacetic acid also suppresses the expression of CYP2E1 .

HY-W271064

1-Methylpyrene	Environmental Pollutants Fluorescent Dye	Others
1-Methylpyrene is a ubiquitous environmental pollutant and rodent carcinogen. Its mutagenic activity depends on sequential activation by various CYP and sulfotransferase (SULT) enzymes. 1-Methylpyrene induces chromosome loss and mitotic disturbance, proba

HY-RS14020

SULT2A1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SULT2A1 Human Pre-designed siRNA Set A contains three designed siRNAs for SULT2A1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SULT2A1 Human Pre-designed siRNA Set A SULT2A1 Human Pre-designed siRNA Set A

HY-RS14015

SULT1A3 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SULT1A3 Human Pre-designed siRNA Set A contains three designed siRNAs for SULT1A3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SULT1A3 Human Pre-designed siRNA Set A SULT1A3 Human Pre-designed siRNA Set A

HY-RS20222

Sult1a1 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Sult1a1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Sult1a1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Sult1a1 Mouse Pre-designed siRNA Set A Sult1a1 Mouse Pre-designed siRNA Set A

HY-RS14013

SULT1A1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SULT1A1 Human Pre-designed siRNA Set A contains three designed siRNAs for SULT1A1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SULT1A1 Human Pre-designed siRNA Set A SULT1A1 Human Pre-designed siRNA Set A

HY-RS20655

Sult4a1 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Sult4a1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Sult4a1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Sult4a1 Mouse Pre-designed siRNA Set A Sult4a1 Mouse Pre-designed siRNA Set A

HY-RS14022

SULT4A1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SULT4A1 Human Pre-designed siRNA Set A contains three designed siRNAs for SULT4A1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SULT4A1 Human Pre-designed siRNA Set A SULT4A1 Human Pre-designed siRNA Set A

HY-RS14014

SULT1A2 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SULT1A2 Human Pre-designed siRNA Set A contains three designed siRNAs for SULT1A2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SULT1A2 Human Pre-designed siRNA Set A SULT1A2 Human Pre-designed siRNA Set A

HY-RS14019

SULT1E1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SULT1E1 Human Pre-designed siRNA Set A contains three designed siRNAs for SULT1E1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SULT1E1 Human Pre-designed siRNA Set A SULT1E1 Human Pre-designed siRNA Set A

HY-RS14018

SULT1C4 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SULT1C4 Human Pre-designed siRNA Set A contains three designed siRNAs for SULT1C4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SULT1C4 Human Pre-designed siRNA Set A SULT1C4 Human Pre-designed siRNA Set A

HY-RS14016

SULT1B1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SULT1B1 Human Pre-designed siRNA Set A contains three designed siRNAs for SULT1B1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SULT1B1 Human Pre-designed siRNA Set A SULT1B1 Human Pre-designed siRNA Set A

HY-RS18107

Sult1e1 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Sult1e1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Sult1e1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Sult1e1 Mouse Pre-designed siRNA Set A Sult1e1 Mouse Pre-designed siRNA Set A

HY-RS14017

SULT1C2 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SULT1C2 Human Pre-designed siRNA Set A contains three designed siRNAs for SULT1C2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SULT1C2 Human Pre-designed siRNA Set A SULT1C2 Human Pre-designed siRNA Set A

HY-RS19554

Sult2b1 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Sult2b1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Sult2b1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Sult2b1 Mouse Pre-designed siRNA Set A Sult2b1 Mouse Pre-designed siRNA Set A

HY-RS14021

SULT2B1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SULT2B1 Human Pre-designed siRNA Set A contains three designed siRNAs for SULT2B1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SULT2B1 Human Pre-designed siRNA Set A SULT2B1 Human Pre-designed siRNA Set A

HY-RS27166

Sult4a1 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Sult4a1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Sult4a1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Sult4a1 Rat Pre-designed siRNA Set A Sult4a1 Rat Pre-designed siRNA Set A

HY-RS20654

Sult2a1 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Sult2a1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Sult2a1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Sult2a1 Mouse Pre-designed siRNA Set A Sult2a1 Mouse Pre-designed siRNA Set A

HY-RS27165

Sult2a1 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Sult2a1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Sult2a1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Sult2a1 Rat Pre-designed siRNA Set A Sult2a1 Rat Pre-designed siRNA Set A

HY-RS26729

Sult1a1 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Sult1a1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Sult1a1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Sult1a1 Rat Pre-designed siRNA Set A Sult1a1 Rat Pre-designed siRNA Set A

HY-RS27164

Sult1c2 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Sult1c2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Sult1c2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Sult1c2 Rat Pre-designed siRNA Set A Sult1c2 Rat Pre-designed siRNA Set A

HY-RS20653

Sult1c2 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Sult1c2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Sult1c2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Sult1c2 Mouse Pre-designed siRNA Set A Sult1c2 Mouse Pre-designed siRNA Set A

HY-RS25068

Sult1b1 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Sult1b1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Sult1b1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Sult1b1 Rat Pre-designed siRNA Set A Sult1b1 Rat Pre-designed siRNA Set A

HY-RS26050

Sult2b1 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Sult2b1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Sult2b1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Sult2b1 Rat Pre-designed siRNA Set A Sult2b1 Rat Pre-designed siRNA Set A

HY-RS18583

Sult1b1 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Sult1b1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Sult1b1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Sult1b1 Mouse Pre-designed siRNA Set A Sult1b1 Mouse Pre-designed siRNA Set A

HY-RS24581

Sult1e1 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Sult1e1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Sult1e1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Sult1e1 Rat Pre-designed siRNA Set A Sult1e1 Rat Pre-designed siRNA Set A

HY-183795

Norethisterone caproate	SULT	Endocrinology
Norethisterone caproate is an impurity of norethisterone that exhibits inhibitory activity against cytosolic sulfotransferase (SULT). Norethisterone caproate inhibits estrus in sexually mature rats during the estrous cycle, displaying long-acting progestogenic activity. Norethisterone caproate can be used in the research of reproductive system diseases .

HY-48813

Glycoursodeoxycholic acid 3-sulfate	Endogenous Metabolite NF-κB Interleukin Related	Metabolic Disease
Glycoursodeoxycholic acid 3-sulfate is a glycine-conjugated sulfated bile acid 3-sulfate, which is produced by SULT2A1-mediated sulfation of glycoursodeoxycholic acid (HY-N1424) in the liver. Glycoursodeoxycholic acid 3-sulfate attenuates the anti-inflammatory effect of glycoursodeoxycholic acid and impairs the inhibitory effect on the IL-17 and NF-κB signaling pathways. Glycoursodeoxycholic acid 3-sulfate shows a significant correlation with aortic flow velocity and BNP in patients with aortic stenosis. Glycoursodeoxycholic acid 3-sulfate is mainly used in related studies such as quantitative analysis, quality control and biochemical experiments; it often serves as a reagent for metabolomics analysis and can also be applied to research related to aortic stenosis .

1-Methylpyrene	Fluorescent Dyes
1-Methylpyrene is a ubiquitous environmental pollutant and rodent carcinogen. Its mutagenic activity depends on sequential activation by various CYP and sulfotransferase (SULT) enzymes. 1-Methylpyrene induces chromosome loss and mitotic disturbance, proba

(Rac)-Metanephrine hydrochloride	Biochemical Assay Reagents
(Rac)-Metanephrine hydrochloride is a metabolite of epinephrine and a substrate of the sulfotransferase *SULT1A3. (Rac)-Metanephrine hydrochloride undergoes sulfonation at its p-hydroxyl group via a reaction catalyzed by SULT1A3*. (Rac)-Metanephrine hydrochloride is an isomer of Metanephrine (HY-113299) hydrochloride, and it is applicable to the research of pheochromocytoma .

Cat. No.	Product Name	Category	Target	Chemical Structure