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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
34 Results for "
SULTs
" in MedChemExpress (MCE) Product Catalog:
Products (34)
34 Results for "SULTs" in MCE Product Catalog:
2
2 Cited Publications
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7-Azido-4-methylcoumarin is a selective coumarin-based fluorescent probe for hydrogen sulfide (H2S). In the presence of H2S, the aromatic azido group of 7-Azido-4-methylcoumarin is selectively reduced to produce the fluorescently active 7-amino-4-methylcoumarin (AMC). 7-Azido-4-methylcoumarin binds to the coumarin/phenol-binding site of BSA, the aglycone-binding site of UGT1A6, and the substrate-binding site of SULT1A1, respectively. 7-Azido-4-methylcoumarin retains its fluorescent properties after covalent binding, acts as a fluorescent H2S probe, and does not react with cysteine, homocysteine or glutathione (Ex/Em = 340/445 nm) .
Cat. No.: HY-113257
CAS No.: 38339-02-5
Synonyms: DA-4S; Dopamine 4-Sulfate
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Dopamine 4-sulfate (DA-4S) is an inactive metabolite of the catecholamine dopamine. It is formed from dopamine by the sulfotransferase (SULT) isoform SULT1A3. Dopamine 4-O-sulfate is found at lower levels in the brain and circulation than dopamine 3-O-sulfate.
Cat. No.: HY-W012206
CAS No.: 881-95-8
Cat. No.: HY-148642
CAS No.: 133627-24-4
Synonyms: 12-hydroxy-NVP; 12-OH-NVP
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12-Hydroxynevirapine (12-hydroxy-NVP; 12-OH-NVP) is a major oxidative metabolite of Nevirapine (HY-10570). Nevirapine is a non-nucleoside reverse transcriptase inhibitor indicated for the HIV-1 infections. Nevirapine causes idiosyncratic hepatotoxicity and mild-to-severe skin rashes. 12-Hydroxynevirapine, a non-reactive metabolite, can be bioactivated by sulphotransferases (SULTs) in the liver and skin, yielding the reactive species 12-Sulphoxy-nevirapine .
Cat. No.: HY-175266
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MI1013 is a PROTAC PXR degrader (DC50 = 89 nM, Dmax = 82%). MI1013 degrades PXR in human hepatocellular carcinoma RG cells (HepaRG). MI1013 specifically and safely regulates CYP3A4 promoter activity through PXR degradation. MI1013 affects several key genes involved in sulfate conjugation (e.g., SULT1E1), bile acid synthesis (CYP7A1), gluconeogenesis (PCK1), ketone synthesis (HMGCS20), and hepatocyte proliferation (MKI67). (Pink: PXR ligand 3: HY-175267, Blue: Pomalidomide-propargyl ligand: HY-W410002, Pink + Black: PXR ligand-Linker Conjugate 1: HY-175268) .
Cat. No.: HY-W271064
CAS No.: 2381-21-7
Cat. No.: HY-RS14013
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SULT1A1 Human Pre-designed siRNA Set A contains three designed siRNAs for SULT1A1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS14014
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SULT1A2 Human Pre-designed siRNA Set A contains three designed siRNAs for SULT1A2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS14015
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SULT1A3 Human Pre-designed siRNA Set A contains three designed siRNAs for SULT1A3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS14020
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SULT2A1 Human Pre-designed siRNA Set A contains three designed siRNAs for SULT2A1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS14022
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SULT4A1 Human Pre-designed siRNA Set A contains three designed siRNAs for SULT4A1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS20222
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Sult1a1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Sult1a1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS20655
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Sult4a1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Sult4a1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS14016
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SULT1B1 Human Pre-designed siRNA Set A contains three designed siRNAs for SULT1B1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS14017
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SULT1C2 Human Pre-designed siRNA Set A contains three designed siRNAs for SULT1C2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS14018
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SULT1C4 Human Pre-designed siRNA Set A contains three designed siRNAs for SULT1C4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS14019
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SULT1E1 Human Pre-designed siRNA Set A contains three designed siRNAs for SULT1E1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS14021
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SULT2B1 Human Pre-designed siRNA Set A contains three designed siRNAs for SULT2B1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS18107
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Sult1e1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Sult1e1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
