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Self-assembling

" in MedChemExpress (MCE) Product Catalog:

214

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27

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130

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40

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7

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4

Isotope-Labeled Compounds

4

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33

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W441011

    Liposome Neurological Disease Inflammation/Immunology Cancer
    DSPE-NHS is a bioconjugation phospholipid molecule with two hydrophobic lipid tails. DSPE-NHS is a self-assembling reagent which forms lipid bilayer in aqueous solution. The NHS-ester is reactive with N-terminal of protein/peptide or other amine molecule to form a stable amide linkage. DSPE-NHS labels antibodies. DSPE-NHS can be used to prepare liposomes as agent nanocarrier .
    DSPE-NHS
  • HY-W014069

    11-Thioundecanoic acid; MUA; MUDA

    Biochemical Assay Reagents Others
    11-Mercaptoundecanoic acid (11-Thioundecanoic acid; MUA; MUDA) is a self-assembled monolayer membrane composed of long-chain alkane chains and carboxyl-containing thioalcohols and can be used as a metal surface modifier. 11-Mercaptoundecanoic acid is widely applied in the research of molecular probes, self-assembled membranes, nanomaterials, and biological materials, etc .
    11-Mercaptoundecanoic acid
  • HY-W048825

    Amino Acid Derivatives Others
    Fmoc-Ala-Ala-OH is a self-assembling fluorenylmethoxycarbonyl dipeptide, a small amphiphilic building block composed of a dipeptide linked to a fluorenylmethoxycarbonyl (Fmoc) group. Under conditions of pH < 4, Fmoc-Ala-Ala-OH spontaneously assembles to form a nanofiber network, constructing a hydrogel scaffold with a water content exceeding 99% (w/w). The fibers have a diameter of approximately 22 nm, matching the size of extracellular matrix (ECM) components. Fmoc-Ala-Ala-OH supports cell adhesion, proliferation, and maintains of cell phenotype. Fmoc-Ala-Ala-OH's function is to mimic the ECM, providing a 3D growth microenvironment for cells, and Fmoc-Ala-Ala-OH is primarily used in tissue engineering and 3D cell culture, particularly suitable for in vitro culture studies of cells such as chondrocytes[1] .
    Fmoc-Ala-Ala-OH
  • HY-W013159

    5′-dGMP disodium

    Endogenous Metabolite Nucleoside Antimetabolite/Analog Metabolic Disease
    2'-Deoxyguanosine 5'-monophosphate (5′-dGMP) disodium is a mononucleotide having guanine as the nucleobase. 2'-Deoxyguanosine 5'-monophosphate disodium is a reactant involved in analysis of self-assembling in solution and nucleation/growth of G-qudruplexes, nucleophilic trapping and reductive alkylation. 2'-Deoxyguanosine 5'-monophosphate disodium can be used as an oxidizable target. 2'-Deoxyguanosine 5'-monophosphate disodium is a nucleic acid guanosine triphosphate (GTP) derivative and is a nucleotide precursor used in DNA synthesis .
    2'-Deoxyguanosine 5'-monophosphate disodium
  • HY-W441007

    Liposome Inflammation/Immunology Cancer
    DSPE-MAL is a phospholipid compound with a maleimide reactive group. DSPE-MAL contains two saturated fatty acids and can self-assemble in water to form a lipid bilayer. DSPE-MAL can be used to prepare liposomes as nanocarriers for active molecules .
    DSPE-Mal
  • HY-P10294

    Amyloid-β Others
    Oligopeptide P11-4 is an α-peptide that can be self-assembled into β-sheet amyloids with a hydrogel appearance at low pH. Oligopeptide P11-4 can be used in biomimetic mineralization, enamel regeneration and oral care agent .
    Oligopeptide P11-4
  • HY-W440719

    Liposome Cancer
    Cholesterol-PEG2000-MAL is a PEG derivative and can be used to prepare liposome or nanoparticle due to its ability to self-assemble in water. The maleimide moiety is reactive with thiol molecule to form a covalent thioether bond.
    Cholesterol-PEG2000-MAL
  • HY-W019833

    PC(14:0/18:0); 1-Myristoyl-2-stearoyl-sn-glycero-3-phosphocholine

    Endogenous Metabolite Metabolic Disease
    MSPC is an asymmetrical phosphatidylcholine containing a myristic acid (14:0) at the sn-1 position and a stearic acid (18:0) at the sn-2 position. It can self assemble in water to form lipid bilayers. Reagent grade, for research purpose.
    MSPC
  • HY-P10709A

    Biochemical Assay Reagents Cardiovascular Disease Cancer
    CREKA peptide acetate is a short peptide sequence, belonging to self-assembling peptides (SAPs), which can self-assemble into functional nanostructures, typically nanofibers, under physiological conditions. CREKA peptide acetate can be used to target tumor cells and tumor vasculature, exhibiting antitumor activity .
    CREKA peptide acetate
  • HY-P2632

    RADA16

    Biochemical Assay Reagents Neurological Disease
    RAD16-I (RADA16) is a non-directed self-assembling peptide hydrogel. Under physiological conditions, RAD16-I spontaneously forms a three-dimensional nanofiber network that mimics the extracellular matrix, and possesses excellent properties such as high water content, biocompatibility and degradability. RAD16-I serves as an ideal scaffold for three-dimensional cell culture. RAD16-I not only maintains cell viability and induces self-organization, but also supports cell adhesion, proliferation, differentiation and insulin secretion, effectively stabilizes islet clusters and promotes directed differentiation of the cardiac lineage. RAD16-I can construct a cell-friendly nano-microenvironment for research related to diseases such as myocardial infarction and diabetes .
    RAD16-I
  • HY-W090210

    MPOH

    Biochemical Assay Reagents Others
    3-Mercapto-1-propanol can be used for the preparation of hydrophilic self-assembled monolayers and as a non-marking linker molecule for chemical and enzymatic synthesis of oligosaccharides .
    3-Mercapto-1-propanol
  • HY-P10659

    EGFR Cancer
    Self-assembling peptide pY1 is a peptide that assemblies around cancer cells and targets EGFR. When co-cultured with Ovalbumin (OVA), pY1 can effectively block the endocytosis of OVA .
    Self-assembling peptide pY1
  • HY-176499
    PLGA38000-PEG10000
    1 Publications Verification

    Biochemical Assay Reagents Others
    PLGA38000-PEG10000 is an amphiphilic polymer. Amphiphilic polymers can be used in drug delivery studies due to their ability to self-assemble into discrete aggregates .
    PLGA38000-PEG10000
  • HY-115419

    Liposome Others
    1-Thio-β-D-glucose sodium is the sodium salt form of 1-Thio-β-D-glucose. 1-Thio-β-D-glucose forms hydrophilic self-assembled monolayer with metal, stablizes the lipid bilayer and protects the proteins from denaturation .
    1-Thio-β-D-glucose sodium
  • HY-P11501

    Amyloid-β Biochemical Assay Reagents Neurological Disease
    AAKLVFF is an oligopeptide capable of self-assembling into nanotubes. AAKLVFF can be derived from the core section of β-amyloid. AAKLVFF becomes the first methanol compatible LC alignment medium for residual dipolar coupling measurement .
    AAKLVFF
  • HY-P10699

    Biochemical Assay Reagents Others
    MAX1 is a self-assembling peptide used to prepare hydrogels .
    MAX1
  • HY-P10701

    Biochemical Assay Reagents Inflammation/Immunology Cancer
    Q11 peptide is a β-sheet-forming peptide that plays an important role in self-assembly and targeted applications. As a scaffold peptide, Q11 peptide can display immunogenic epitopes and is widely used in peptide-based immune vaccine research. Additionally, Q11 peptide can be conjugated with MUC1 glycopeptides for the study of self-assembling, adjuvant-free MUC1 glycopeptide vaccines. Q11 peptide holds great potential for research in the field of cancer immunology .
    Q11 peptide
  • HY-W013159S

    5′-dGMP-13C10,15N5 disodium

    Isotope-Labeled Compounds Endogenous Metabolite Nucleoside Antimetabolite/Analog Metabolic Disease
    2'-Deoxyguanosine 5'-monophosphate- 13C10, 15N5 (dGMP- 13C10, 15N5) disodium is the 13C and 15N labeled 2'-Deoxyguanosine 5'-monophosphate disodium (HY-W013159). 2'-Deoxyguanosine 5'-monophosphate (5′-dGMP) disodium is a mononucleotide having guanine as the nucleobase. 2'-Deoxyguanosine 5'-monophosphate disodium is a reactant involved in analysis of self-assembling in solution and nucleation/growth of G-qudruplexes, nucleophilic trapping and reductive alkylation. 2'-Deoxyguanosine 5'-monophosphate disodium can be used as an oxidizable target. 2'-Deoxyguanosine 5'-monophosphate disodium is a nucleic acid guanosine triphosphate (GTP) derivative and is a nucleotide precursor used in DNA synthesis .
    2'-Deoxyguanosine 5'-monophosphate-13C10,15N5 disodium
  • HY-P11309

    Biochemical Assay Reagents Neurological Disease
    QL6 peptide is a self-assembling peptide. QL6 peptide can self-assembles into β-sheets bridging the cavity at neutral pH and improves the inhibitory environment by reducing inflammation and tissue scaring. QL6 peptide can be used for synthesis nanofiber scaffolds for spinal cord injuries (SCI) research .
    QL6 peptide
  • HY-P10712

    Biochemical Assay Reagents Others
    Nap-GFFY, a naphthylacetic acid modifi ed tetrapeptide of GFFY, is a self-assembling fiber peptide .
    Nap-GFFY
  • HY-P10675

    Biochemical Assay Reagents Metabolic Disease
    Peptide K is a self-assembling peptide fiber that can be used to prepare fibrous nanocomposite hydrogels. The fibrous nanocomposite hydrogels have a dynamic network that adapts to cells and enhances cell-matrix and cell-cell interactions, thus significantly promoting the mechanotransduction, metabolic energy, and osteogenesis of encapsulated stem cells .
    Peptide K
  • HY-W014069R

    11-Thioundecanoic acid (Standard); MUA (Standard); MUDA (Standard)

    Reference Standards Biochemical Assay Reagents Others
    11-Mercaptoundecanoic acid (Standard) is an analytical standard of 11-Mercaptoundecanoic acid (HY-W014069R). This product is used for research and analytical applications. 11-Mercaptoundecanoic acid is a self-assembled monolayer membrane composed of long-chain alkane chains and carboxyl-containing thioalcohols and can be used as a metal surface modifier. 11-Mercaptoundecanoic acid is widely applied in the research of molecular probes, self-assembled membranes, nanomaterials, and biological materials, etc .
    11-Mercaptoundecanoic acid (Standard)
  • HY-P10706

    Biochemical Assay Reagents Others
    Ac-ILVAGK-NH2 is a self-assembling peptide that helps human H1 embryonic stem cells maintain their pluripotency .
    Ac-ILVAGK-NH2
  • HY-167006

    PLGA10000-PEG3000-Vinylsulfone

    Biochemical Assay Reagents Others
    PLGA10000-PEG3000-VS (PLGA10000-PEG3000-Vinylsulfone) is an amphiphilic polymer. Amphiphilic polymers can be used in drug delivery studies due to their ability to self-assemble into discrete aggregates .
    PLGA10000-PEG3000-VS
  • HY-P10494

    Amyloid-β Neurological Disease
    FEFEFKFK is an octapeptide that self-assembles into fibrillar structures. FEFEFKFK is able to form gels at concentrations greater than about 7 mg/mL. The self-assembly and gelation properties of FEFEFKFK help to understand the mechanism of amyloid fibril formation in protein misfolding diseases such as Alzheimer's disease and Parkinson's disease .
    FEFEFKFK
  • HY-P11055

    Bacterial Infection
    IKFQFHFD is a pH-responsive and self-assembling peptide. IKFQFHFD is biocompatible at neutral pH and becomes an antimicrobial peptide-like molecular structure only at acidic pH. IKFQFHFD can be used for chronic wounds (venous ulcers, diabetic ulcers, and pressure ulcers) induced by biofilm infections research .
    IKFQFHFD
  • HY-P10705

    Biochemical Assay Reagents Cancer
    KGFRWR is a short peptide sequence, belonging to self-assembling peptides (SAPs), which can self-assemble into functional nanostructures, typically nanofibers, under physiological conditions. KGFRWR can be used to target tumor cells and tumor vasculature, exhibiting antitumor activity .
    KGFRWR
  • HY-P6079A

    Biochemical Assay Reagents Others
    Ac-IHIHIYI-NH2 TFA is an amyloid self-assembling peptide variant that can be used as a bioactive nanomaterial with esterase activity .
    Ac-IHIHIYI-NH2 TFA
  • HY-P10702

    Biochemical Assay Reagents Others
    SAF-p1 is a self-assembling fiber peptide that can form sticky-ended heterodimers by assembling with SAF-p2 (HY-P10703) through complementary amino acid sequences. These heterodimers further self-assemble into long-chain fiber structures. SAF-p1 is promising for the development of nanomaterials in the biomedical field .
    SAF-p1
  • HY-P10703

    Biochemical Assay Reagents Others
    SAF-p2 is a self-assembling fiber peptide that can form sticky-ended heterodimers by assembling with SAF-p2 (HY-P10702) through complementary amino acid sequences. These heterodimers further self-assemble into long-chain fiber structures. SAF-p2 is promising for the development of nanomaterials in the biomedical field .
    SAF-p2
  • HY-158373

    Autophagy Cancer
    Anticancer agent 213 (Compound 1) exhibits anticancer efficacy by self-assembling into micelles, depleting membran cholesterol and thus inhibiting cancer cells. Anticancer agent 213 exhibits cytotoxicity against HeLa and PC3, with IC50 of 10.3 and 13.7 μM. Anticancer agent 213 induces autophagy .
    Anticancer agent 213
  • HY-W440907

    Biochemical Assay Reagents Others
    DSPE-PEG5000-Vinylsulfone is a viniyl sulfone PEG lipid which can be used for bioconjugation with cysteine or other thiol molecule through thiol-ene reaction. The polymer is a self-assembling reagetn which forms lipid bilayer in water and can be used as drug carrier to delivery therapeutic agents, such as mRNA or DNA vaccine.
    DSPE-PEG5000-Vinylsulfone
  • HY-W440905

    Biochemical Assay Reagents Others
    DSPE-PEG2000-Vinylsulfone is a viniyl sulfone PEG lipid which can be used for bioconjugation with cysteine or other thiol molecule through thiol-ene reaction. The polymer is a self-assembling reagetn which forms lipid bilayer in water and can be used as drug carrier to delivery therapeutic agents, such as mRNA or DNA vaccine.
    DSPE-PEG2000-Vinylsulfone
  • HY-W440904

    Biochemical Assay Reagents Others
    DSPE-PEG1000-Vinylsulfone is a viniyl sulfone PEG lipid which can be used for bioconjugation with cysteine or other thiol molecule through thiol-ene reaction. The polymer is a self-assembling reagetn which forms lipid bilayer in water and can be used as drug carrier to delivery therapeutic agents, such as mRNA or DNA vaccine.
    DSPE-PEG1000-Vinylsulfone
  • HY-156087G

    Apoptosis Necroptosis Cancer
    Cholicamideβ (GMP) is a GMP grade of Cholicamideβ. Cholicamideβ (compound 6) is a self-assembling, small molecule, cancer vaccine adjuvant. Cholicamideβ can form virus-like particles with low cytotoxicity. Cholicamideβ, upon binding to peptide antigens, enhances antigen presentation by dendritic cells and induces antigen-specific T cells. Cholicamideβ can induce apoptosis and necrosis .
    Cholicamideβ (GMP)
  • HY-156087

    Apoptosis Necroptosis Cancer
    Cholicamideβ (GMP) is a GMP grade of Cholicamideβ. Cholicamideβ (compound 6) is a self-assembling, small molecule, cancer vaccine adjuvant. Cholicamideβ can form virus-like particles with low cytotoxicity. Cholicamideβ, upon binding to peptide antigens, enhances antigen presentation by dendritic cells and induces antigen-specific T cells. Cholicamideβ can induce apoptosis and necrosis .
    Cholicamideβ
  • HY-167071

    Biochemical Assay Reagents Others
    PLLA-azide (MW 5000) is a polylactic acid derivative that can self-assemble in water. PLLA-azide (MW 5000) can be used in drug delivery research .
    PLLA-azide (MW 5000)
  • HY-167117

    Biochemical Assay Reagents Others
    PLLA-azide (MW 10000) is a polylactic acid derivative that can self-assemble in water. PLLA-azide (MW 10000) can be used in drug delivery research .
    PLLA-azide (MW 10000)
  • HY-W440892

    Biochemical Assay Reagents Others
    DSPE-PEG3400-OH is an amphiphilic polydisperse PEG which can spontaneously self-assemble in aqueous solution. The polymer can be used to prepare liposoome for targeted drug delivery.
    DSPE-PEG3400-OH
  • HY-W590593

    Liposome Cancer
    mPEG-Cholesterol,MW 2000 is a PEG derivative which self-assembles in water to form micelle-like structure. The cholesterol tail can be used to encapsulate hydrophobic drugs while the PEG chain ehances the water solubility of the micelles.
    mPEG-Cholesterol (MW 2000)
  • HY-W440928

    Liposome Others
    Stearic acid-PEG3400-NHS is a phospholipid polyPEG which can self-assemble in water to form lipid bilayer. The polymer can be used to prepare liposomes as drug carrier to deliver nutrients/therpeutic agents, such as mRNA or DNA.
    Stearic acid-PEG3400-NHS
  • HY-W591913

    Liposome Cancer
    Cholesterol-PEG2000-methoxy is a PEG derivative which self-assembles in water to form micelle-like structure. The cholesterol tail can be used to encapsulate hydrophobic drugs while the PEG chain ehances the water solubility of the micelles.
    Cholesterol-PEG2000-methoxy
  • HY-P4579

    Biochemical Assay Reagents Others
    Pyr-Phe-OH is an effective pyrene-based hydrogel. Pyr Phe OH can self-assemble into hydrogels in the range of pH=7.5-14.0, and also shows a very low gel concentration (0.037% (w/v)) in phosphate buffer .
    Pyr-Phe-OH
  • HY-167055

    PLLA4000-PEG2000-Vinylsulfone

    Biochemical Assay Reagents Others
    PLLA4000-PEG2000-VS (PLLA4000-PEG2000-Vinylsulfone) is an amphiphilic polymer. Amphiphilic polymers can be used in drug delivery studies due to their ability to self-assemble into discrete aggregates .
    PLLA4000-PEG2000-VS
  • HY-167033

    PLGA4000-PEG5000-Vinylsulfone

    Biochemical Assay Reagents Others
    PLGA4000-PEG5000-VS (PLGA4000-PEG5000-Vinylsulfone) is an amphiphilic polymer. Amphiphilic polymers can be used in drug delivery studies due to their ability to self-assemble into discrete aggregates .
    PLGA4000-PEG5000-VS
  • HY-167047

    PLLA5000-PEG1000-Vinylsulfone

    Biochemical Assay Reagents Others
    PLLA5000-PEG1000-VS (PLLA5000-PEG1000-Vinylsulfone) is an amphiphilic polymer. Amphiphilic polymers can be used in drug delivery studies due to their ability to self-assemble into discrete aggregates .
    PLLA5000-PEG1000-VS
  • HY-167035

    PLGA5000-PEG2000-Vinylsulfone

    Biochemical Assay Reagents Others
    PLGA5000-PEG2000-VS (PLGA5000-PEG2000-Vinylsulfone) is an amphiphilic polymer. Amphiphilic polymers can be used in drug delivery studies due to their ability to self-assemble into discrete aggregates .
    PLGA5000-PEG2000-VS
  • HY-W440906

    Biochemical Assay Reagents Others
    DSPE-PEG3400-Vinylsulfone is a viniyl sulfone PEG lipid which can be used for bioconjugation with cysteine or other thiol molecule through thiol-ene reaction. The polymer is a self-assembling reagetn which forms lipid bilayer in water and can be used as drug carrier to delivery therapeutic agents, such as mRNA or DNA vaccine.
    DSPE-PEG3400-Vinylsulfone
  • HY-P11468

    Bacterial Antibiotic Cardiovascular Disease Infection
    wkwkwNGwkwkw-NH2 is a self-assembling β-hairpin antimicrobial peptide. wkwkwNGwkwkw-NH2 self-assembles into nanofibers. wkwkwNGwkwkw-NH2 interacts with LPS on the surface of the bacterial membrane and then disrupts the bacterial outer membrane, inner membrane, and cytoplasmic membrane to exert its antibacterial effects. wkwkwNGwkwkw-NH2 has high antibacterial activity and low hemolytic activity. wkwkwNGwkwkw-NH2 significantly reduces the S. aureus ATCC 25923 load at the skin wound. wkwkwNGwkwkw-NH2 displays synergistic effects when combined with antibiotics. wkwkwNGwkwkw-NH2 facilitates wound healing .
    wkwkwNGwkwkw-NH2
  • HY-137247

    Biochemical Assay Reagents Others
    16-Mercaptopalmitic acid is a chain alkylmercaptan with a long -CH2 group that forms a self-assembled monolayer (SAM) on a variety of substrates .
    16-Mercaptopalmitic acid

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