2'-Deoxyguanosine 5'-monophosphate disodium
Based on 1 publication(s) in Google Scholar
2'-Deoxyguanosine 5'-monophosphate (5′-dGMP) disodium is a mononucleotide having guanine as the nucleobase. 2'-Deoxyguanosine 5'-monophosphate disodium is a reactant involved in analysis of self-assembling in solution and nucleation/growth of G-qudruplexes, nucleophilic trapping and reductive alkylation. 2'-Deoxyguanosine 5'-monophosphate disodium can be used as an oxidizable target. 2'-Deoxyguanosine 5'-monophosphate disodium is a nucleic acid guanosine triphosphate (GTP) derivative and is a nucleotide precursor used in DNA synthesis.
For research use only. We do not sell to patients.
- Purity : 99.85%
- CAS No.: 33430-61-4
- Formula: C10H12N5Na2O7P
- Molecular Weight:391.18
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Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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HY-W016009
2'-Deoxyadenosine-5'-monophosphate -
HY-128738
Thymidine-5'-monophosphate disodium salt -
HY-A0181
Adenosine monophosphate -
HY-N0097
Guanosine -
HY-N1150
Thymidine -
HY-W009216
2'-Deoxycytidine-5'-monophosphate -
HY-17563
2'-Deoxyguanosine -
HY-113066A
Guanosine 5'-diphosphate disodium salt -
HY-I0400
N-Acetylneuraminic acid -
HY-W008638
2'-Deoxyinosine -
HY-W011142
2'-Deoxyuridine 5'-monophosphate disodium -
HY-W009162
Cytidine 5'-monophosphate
Publications Citing Use of MedChemExpress (MCE) 2'-Deoxyguanosine 5'-monophosphate disodium
MoreAll Endogenous Metabolite Isoforms
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Biological Activity
Description
In Vitro
Guanine, the nucleobase of 2'-Deoxyguanosine 5'-monophosphate (5′-dGMP) disodium, is the preferential DNA substrate of photooxidations via electron transfer or hydrogen abstraction (type I mechanism) and is the only DNA constituent that significantly reacts with 1O2 (type II mechanism). Therefore, molecules bearing guanine are good substrates to evaluate biologicallyrelevant photosensitizing properties[1].
2'-Deoxyguanosine 5'-monophosphate disodium can be used to evaluate the photosensitivity of lumazine (Lum). In the 2'-Deoxyguanosine 5'-monophosphate disodiumexperiments, the data revealed that 2'-Deoxyguanosine 5'-monophosphate indeed undergoes oxidation/oxygenation photoinduced by Lum[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 33430-61-4
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Appearance Solid
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Molecular Weight 391.18
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Formula C10H12N5Na2O7P
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Color White to off-white
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SMILES
O[C@H]1C[C@H](N2C(N=C(N)NC3=O)=C3N=C2)O[C@@H]1COP(O[Na])(O[Na])=O
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Synonyms
5′-dGMP disodium
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Publications (1)
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Journal Impact Factor
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Most Recent
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Nature
2025 Jul;643(8070):192-200. PMID: 39695227
Solvent & Solubility
In Vitro:
H2O : 111.11 mg/mL (284.04 mM; Need ultrasonic)
DMSO : < 1 mg/mL (insoluble or slightly soluble)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
In Vivo:
For the following dissolution methods, please prepare the working solution directly:
It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: PBS
Solubility: 100 mg/mL (255.64 mM); Clear solution; Need ultrasonic
Purity & Documentation
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Data Sheet (275 KB)
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SDS (396 KB)
- English - EN (396 KB)
- Français - FR (396 KB)
- Deutsch - DE (396 KB)
- Norwegian - NO (396 KB)
- Español - ES (396 KB)
- Swedish - SV (396 KB)
- Italian - IT (396 KB)
- Korean - KR (396 KB)
- Portuguese - PT (396 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 2.5564 mL | 12.7818 mL | 25.5637 mL | 63.9092 mL |
| 5 mM | 0.5113 mL | 2.5564 mL | 5.1127 mL | 12.7818 mL | |
| 10 mM | 0.2556 mL | 1.2782 mL | 2.5564 mL | 6.3909 mL | |
| 15 mM | 0.1704 mL | 0.8521 mL | 1.7042 mL | 4.2606 mL | |
| 20 mM | 0.1278 mL | 0.6391 mL | 1.2782 mL | 3.1955 mL | |
| 25 mM | 0.1023 mL | 0.5113 mL | 1.0225 mL | 2.5564 mL | |
| 30 mM | 0.0852 mL | 0.4261 mL | 0.8521 mL | 2.1303 mL | |
| 40 mM | 0.0639 mL | 0.3195 mL | 0.6391 mL | 1.5977 mL | |
| 50 mM | 0.0511 mL | 0.2556 mL | 0.5113 mL | 1.2782 mL | |
| 60 mM | 0.0426 mL | 0.2130 mL | 0.4261 mL | 1.0652 mL | |
| 80 mM | 0.0320 mL | 0.1598 mL | 0.3195 mL | 0.7989 mL | |
| 100 mM | 0.0256 mL | 0.1278 mL | 0.2556 mL | 0.6391 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
2'-Deoxyguanosine 5'-monophosphate disodium Related Classifications
HY-W013159 Related Classifications
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