11-Mercaptoundecanoic acid
Based on 1 Customer Validation
11-Mercaptoundecanoic acid (11-Thioundecanoic acid; MUA; MUDA) is a self-assembled monolayer membrane composed of long-chain alkane chains and carboxyl-containing thioalcohols and can be used as a metal surface modifier. 11-Mercaptoundecanoic acid is widely applied in the research of molecular probes, self-assembled membranes, nanomaterials, and biological materials, etc.
For research use only. We do not sell to patients.
- Purity: 99.84%
- CAS No.: 71310-21-9
- Formula: C11H22O2S
- Molecular Weight:218.36
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
11-Mercaptoundecanoic acid is capped gold nanoclusters with unusual aggregation-enhanced emission for selective fluorometric hydrogen sulfide determination[1].
11-Mercaptoundecanoic acid is used to modify electrochemical immunosensor for screening of polycyclic aromatic hydrocarbons in water[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
| NCT Number | Sponsor | Condition | Start Date |
Phase
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|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 71310-21-9
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Appearance Solid
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Molecular Weight 218.36
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Formula C11H22O2S
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Color White to off-white
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SMILES
O=C(O)CCCCCCCCCCS
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Synonyms
11-Thioundecanoic acid; MUA; MUDA
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 200 mg/mL (915.92 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.5 mg/mL (11.45 mM); Clear solution
This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 2.5 mg/mL (11.45 mM); Clear solution
This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL.
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
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Data Sheet (266 KB)
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SDS (396 KB)
- English - EN (396 KB)
- Français - FR (396 KB)
- Deutsch - DE (396 KB)
- Norwegian - NO (396 KB)
- Español - ES (396 KB)
- Swedish - SV (396 KB)
- Italian - IT (396 KB)
- Korean - KR (396 KB)
- Portuguese - PT (396 KB)
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Handling Instructions (2659 KB)
References
[1]. Lu F, et al. 11-Mercaptoundecanoic acid capped gold nanoclusters with unusual aggregation-enhanced emission for selective fluorometric hydrogen sulfide determination. Mikrochim Acta. 2020 Mar 4;187(4):200. [Content Brief]
[2]. Ahmad A, et al. Electrochemical immunosensor modified with self-assembled monolayer of 11-mercaptoundecanoic acid on gold electrodes for detection of benzo[a]pyrene in water. Analyst. 2012 Dec 21;137(24):5839-44. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 4.5796 mL | 22.8980 mL | 45.7959 mL | 114.4898 mL |
| 5 mM | 0.9159 mL | 4.5796 mL | 9.1592 mL | 22.8980 mL | |
| 10 mM | 0.4580 mL | 2.2898 mL | 4.5796 mL | 11.4490 mL | |
| 15 mM | 0.3053 mL | 1.5265 mL | 3.0531 mL | 7.6327 mL | |
| 20 mM | 0.2290 mL | 1.1449 mL | 2.2898 mL | 5.7245 mL | |
| 25 mM | 0.1832 mL | 0.9159 mL | 1.8318 mL | 4.5796 mL | |
| 30 mM | 0.1527 mL | 0.7633 mL | 1.5265 mL | 3.8163 mL | |
| 40 mM | 0.1145 mL | 0.5724 mL | 1.1449 mL | 2.8622 mL | |
| 50 mM | 0.0916 mL | 0.4580 mL | 0.9159 mL | 2.2898 mL | |
| 60 mM | 0.0763 mL | 0.3816 mL | 0.7633 mL | 1.9082 mL | |
| 80 mM | 0.0572 mL | 0.2862 mL | 0.5724 mL | 1.4311 mL | |
| 100 mM | 0.0458 mL | 0.2290 mL | 0.4580 mL | 1.1449 mL |
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