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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
5 Results for "
Ser195
" in MedChemExpress (MCE) Product Catalog:
Products (5)
5 Results for "Ser195" in MCE Product Catalog:
Cat. No.: HY-155231
Neutrophil elastase inhibitor 4 is a human neutrophil elastase (HNE) inhibitor with an IC50 of 21.78 nM and a Ki of 8.04 nM. Neutrophil elastase inhibitor 4 induces G2/M cell cycle arrest and apoptosis. Neutrophil elastase inhibitor 4 is applicable to research related to breast cancer, multiple myeloma and non-small cell lung cancer .
Cat. No.: HY-P0007
CAS No.: 60731-46-6
Synonyms: Carbocalcitonin
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Cat. No.: HY-184117B
CAS No.: 3098808-75-1
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(R)-pMeO-Bz-SF, the R isomer of pMeO-Bz-SF (HY-184117), is an α-chymotrypsin inhibitor with an IC50 of 101 nM. (R)-pMeO-Bz-SF covalently modifies Ser195, Ser190, and Tyr146 in or near α-chymotrypsin’s hydrophobic S1 binding pocket. (R)-pMeO-Bz-SF inhibits α-chymotrypsin in a stereoselective manner .
Cat. No.: HY-184117A
CAS No.: 3117686-58-2
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(S)-pMeO-Bz-SF, the S isomer of pMeO-Bz-SF (HY-184117A), is a potent covalent serine hydrolase inhibitor with an α-chymotrypsin IC50 of 2.965 μM. (S)-pMeO-Bz-SF covalently modifies α-chymotrypsin residues Ser195, Tyr146, and Ser190. (S)-pMeO-Bz-SF exhibits stereoselective inhibitory activity against α-chymotrypsin .
Cat. No.: HY-184117
CAS No.: 3061644-67-2
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pMeO-Bz-SF is a covalent, stereoselective α-chymotrypsin inhibitor with an IC50 value of 133 nM. The (R)-enantiomer of pMeO-Bz-SF ((R)-pMeO-Bz-SF (HY-184117B)) inhibits α-chymotrypsin with an IC50 of 101 nM. The (S)-enantiomer of pMeO-Bz-SF ((S)-pMeO-Bz-SF (HY-184117A)) shows low activity against α-chymotrypsin, with an IC50 of 2965 nM .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
