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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
11 Results for "
TCL 1
" in MedChemExpress (MCE) Product Catalog:
Products (11)
11 Results for "TCL 1" in MCE Product Catalog:
Cat. No.: HY-18676B
CAS No.: 1333146-24-9
Synonyms: OSU-T315 analog
ILK-IN-2 (OSU-T315 analog) is an oral PDK2 inhibitor and also an ILK inhibitor, with an IC50 of 0.6 μM. ILK-IN-2 induces cell autophagy and apoptosis, showing anti-tumor activity. ILK-IN-2 directly abolishes AKT activation by preventing AKT from translocating to lipid rafts, triggering Caspase-dependent apoptosis in chronic lymphocytic leukemia (CLL) and extending the lifespan in TCL1 mouse models .
Cat. No.: HY-159808
CAS No.: 875165-39-2
Target:
Research Areas:
TCL1 is a selective non-covalent inhibitor targeting the Pru domain of the Rpn-13 subunit in the 19S regulatory particle (19S RP) of the proteasome with an IC50 value of approximately 26 μM. TCL1 interferes with the recognition and transport of ubiquitinated proteins by Rpn-13, inhibits the degradation of proteins by the proteasome, and thus affects the balance of intracellular protein metabolism. TCL1 is promising for research of hematological malignancies .
Cat. No.: HY-P10105
CAS No.: 835655-37-3
Cat. No.: HY-P10049
CAS No.: 1073630-46-2
Cat. No.: HY-RS14316
Target:
Research Areas:
TCL1A Human Pre-designed siRNA Set A contains three designed siRNAs for TCL1A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS14317
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Research Areas:
TCL1B Human Pre-designed siRNA Set A contains three designed siRNAs for TCL1B gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P85928
Synonyms: Anti TCL1A; Lymphoma/leukemia, T-cell; Oncogene TCL-1; Oncogene TCL1; P14 TCL1; P14 TCL1 protein; Protein p14 TCL1; T cell leukemia 1; T cell lymphoma 1; T cell lymphoma 1A; T-cell leukemia/lymphoma 1A; T-cell leukemia/lymphoma protein 1A; TCL 1 protein; TCL1; TCL1 oncogene; TCL1 PEN; TCL1a; TCL1A; TCL1A_HUMAN
Cat. No.: HY-RS25978
Target:
Research Areas:
Tcl1a Rat Pre-designed siRNA Set A contains three designed siRNAs for Tcl1a gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-N8177
CAS No.: 2292159-89-6
Category:
Bletilla striata (Thunb. ex Murray) Rchb. f. Simple Phenylpropanols Orchidaceae Other Diseases Phenylpropanoids Plants Disease Research Fields
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
