3 Results for "

TLR4/MyD88 binding

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "TLR4/MyD88 binding" in MCE Product Catalog:

Cat. No.: HY-154438
CAS No.: 4155-82-2
Purity:  ≥98.0%
RDR 02308 is a TLR4-MyD88 binding inhibitor that inhibits full-length β-lactamase .
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Cat. No.: HY-180336
CAS No.: 2249864-11-5
LM9 is a potent, orally active MyD88 inhibitor. LM9 blocks TLR4/MyD88 binding, MyD88 homodimer formation, and TLR4/MyD88/NF-κB signaling pathway activation. LM9 prevents atherosclerosis by regulating inflammatory responses and oxidative stress in macrophages. LM9 efficiently mitigates inflammatory responses and fibrosis in obesity-induced cardiomyopathy. LM9 can be used for fibrosis and atherosclerosis research .
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Cat. No.: HY-125447
CAS No.: 145941-07-7
Artemisinin B is an orally active sesquiterpene natural product with anti-neuroinflammatory activity, which can be found in Artemisia annua Linn.. Artemisinin B suppresses the TLR4-MyD88-NF-κB signaling pathway by reducing the protein levels of TLR4 and MyD88, as well as inhibiting the mRNA expression of NF-κB p65. Artemisinin B reduces the expression of pro-inflammatory cytokines and attenuates synaptic loss, which can be used for the research of cognitive and behavioral impairments in Alzheimer's disease. Artemisinin B shows no cytotoxicity against human cardiomyocytes and exhibits very weak binding to hERG, suggesting its potential for cardioprotective property research .
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