1 Result for "

UCI1014

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "UCI1014" in MCE Product Catalog:

Cat. No.: HY-183622
CAS No.: 304896-41-1
Target:  

MDM-2/p53

Research Areas:  

Cancer

UCI-1014 is a mutant p53 (p53 R175H) corrector/reactivator. UCI-1014 restores the wild-type-like DNA-binding activity of p53 R175H, promotes the redistribution of the mutant protein to chromatin, and induces the expression of p53-dependent target genes. UCI-1014 inhibits the proliferation of p53 R175H-mutant cancer cells through an SLC7A11-independent mechanism. UCI-1014 can be used for research related to p53-mutant cancers .
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