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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
5 Results for "
UGT1A7
" in MedChemExpress (MCE) Product Catalog:
Products (5)
5 Results for "UGT1A7" in MCE Product Catalog:
Cat. No.: HY-RS15431
Target:
Research Areas:
UGT1A7 Human Pre-designed siRNA Set A contains three designed siRNAs for UGT1A7 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-E72109
Human UGT1A7 is a UDP-glucuronosyltransferase. UGT1A7 catalyzes the glucuronidation of hydrophobic substrates, polycyclic aromatic hydrocarbons, dietary heterocyclic amines, and 1-Hydroxypyrene (HY-W014075). Human UGT1A7 is applicable to research related to sporadic colorectal cancer .
Research Areas:
16-Epiestriol (16-epi-Estriol; 16β,17β-Estriol) is a natural stereoisomer of estriol and an anti-inflammatory agent that targets UGT. The Ki values of 16-Epiestriol against human UGT1A10 and UGT2B7 are 98.1 μM and 162 μM, respectively. As a glucuronidation substrate, 16-Epiestriol can be modified at the 3-OH, 16-OH and 17-OH sites by various UGT enzymes; in liver microsomes, the modification mainly occurs at the 16-OH and 17-OH sites, while reactions take place at all three sites in intestinal microsomes. 16-Epiestriol acts on the phase II inflammatory process by blocking edema mediated by prostaglandins and leukocyte infiltration. It lacks glycogenic activity or any effect on blood glucose levels, and serves as an important candidate molecule in the research of inflammatory diseases .
Category:
Infection Alkaloids other families Monophenols Phenols Quinoline Alkaloids Plants Disease Research Fields
Target:
Cat. No.: HY-D3180
CAS No.: 1201643-01-7
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
