1201643-01-7
1201643-01-7
Chemical Structure
CDr20
- CAS No.: 1201643-01-7
- Formula:C19H17BF2N2O2
- Molecular Weight:354.16
InChIKey: JZMZTXFEQXWOGQ-FNORWQNLSA-N
SMILES: [F-][B+3]1([N]2=CC=CC2=CC3=C(C)C=C([N-]31)/C=C/C4=CC=C(C(O)=C4)OC)[F-]
Biological Activity: CDr20 is a fluorescent chemical probe capable of crossing the blood-brain barrier. CDr20 undergoes glucuronidation catalyzed by the UDP-glucuronosyltransferase Ugt1a7c, which triggers a fluorescence turn-on response. CDr20 enables visualization of live microglial cells. CDr20 can be used for research on Alzheimer's disease, stroke, and autism[1].
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CDr20 | CDr20 is a fluorescent chemical probe capable of crossing the blood-brain barrier. CDr20 undergoes glucuronidation catalyzed by the UDP-glucuronosyltransferase Ugt1a7c, which triggers a fluorescence turn-on response. CDr20 enables visualization of live microglial cells. CDr20 can be used for research on Alzheimer's disease, stroke, and autism. | |||||||||||||||||||||
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References
Keywords
