1 Result for "

UNC8153 TFA

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "UNC8153 TFA" in MCE Product Catalog:

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Cat. No.: HY-157251
CAS No.: 2929304-61-8
Pureté:  99.92%
Domaines de recherche:  

Cancer

UNC8153 TFA is a potent and selective nuclear receptor-binding SET domain-containing 2 (NSD2)-targeted degrader with a Kd of 24 nM. UNC8153 TFA reduces the cellular levels of both NSD2 protein (DC50 in cell U2OS is 0.35 μM) and the H3K36me2 chromatin mark. UNC8153 TFA contains a simple warhead that confers proteasome-dependent degradation of NSD2 .
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