1 Result for "

VU6066098

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "VU6066098" in MCE Product Catalog:

Cat. No.: HY-184596
CAS No.: 3055537-47-5
Target:  

mGluR

Research Areas:  

Neurological Disease

VU6066098 is a blood-brain barrier penetrant, orally active inhibitor of metabotropic glutamate receptor subtype 2 (mGlu2), with IC50 values of 77 nM and 111 nM against human and rat targets, respectively. VU6066098 induces antidepressant-like activity, inhibits psychosis-like hyperlocomotion, enhances recognition memory and associative learning, and reverses cognitive deficits caused by blast-related traumatic brain injury. VU6066098 can be used in research on major depressive disorder, schizophrenia, Alzheimer's disease, and traumatic brain injury .
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