29 Results for "

abiraterone

" in MedChemExpress (MCE) Product Catalog:
Products (29)

29 Results for "abiraterone" in MCE Product Catalog:

24
24 Publications Verification
Cat. No.: HY-70013
CAS No.: 154229-19-3
Synonyms: CB-7598
Target:  

Cytochrome P450

Research Areas:  

Cancer

Abiraterone is a potent and irreversible CYP17A1 inhibitor with antiandrogen activity, which inhibits both the 17α-hydroxylase and 17,20-lyase activity of the cytochrome p450 enzyme CYP17 with IC50s of 2.5 nM and 15 nM, respectively.
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24
24 Publications Verification
Cat. No.: HY-75054
CAS No.: 154229-18-2
Synonyms: CB7630
Target:  

Cytochrome P450

Research Areas:  

Cancer

Abiraterone acetate (CB7630) is an oral, potent, selective, and irreversible inhibitor of CYP17A1 with antiandrogen activity. Abiraterone acetate is a proagent form of Abiraterone (CB7598).
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2
2 Cited Publications
Cat. No.: HY-W013205
CAS No.: 645-15-8
Synonyms: BNPP
Research Areas:  

Others

Bis(4-nitrophenyl) phosphate (BNPP) is an esterase inhibitor, inhibits the activity of esterases such as carboxylesterase. Bis(4-nitrophenyl) phosphate inhibits the degradation of Abiraterone in fresh plasma. Bis(4-nitrophenyl) phosphate can be used as a substrate to determine the enzymatic activity of phosphodiesterase in the roots of wetland plants. Bis(4-nitrophenyl) phosphate also acts as a catalyst for metallomicelles and a catalyst that promotes ring-opening polymerization (ROP) .
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2
2 Cited Publications
Cat. No.: HY-W013205B
CAS No.: 4043-96-3
Synonyms: BNPP sodium
Bis(4-nitrophenyl) phosphate sodium (BNPP sodium) is an esterase inhibitor, inhibits the activity of esterases such as carboxylesterase. Bis(4-nitrophenyl) phosphate sodium inhibits the degradation of Abiraterone in fresh plasma. Bis(4-nitrophenyl) phosphate sodium can be used as a substrate to determine the enzymatic activity of phosphodiesterase in the roots of wetland plants. Bis(4-nitrophenyl) phosphate sodium also acts as a catalyst for metallomicelles and a catalyst that promotes ring-opening polymerization (ROP) .
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Cat. No.: HY-70013S
CAS No.: 2122245-62-7
Synonyms: CB-7598-d4
Abiraterone-d4 is the deuterium labeled Abiraterone. Abiraterone is a potent and irreversible CYP17A1 inhibitor with antiandrogen activity, which inhibits both the 17α-hydroxylase and 17,20-lyase activity of the cytochrome p450 enzyme CYP17 with IC50s of 2.5 nM and 15 nM, respectively.
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Cat. No.: HY-109619
CAS No.: 154229-21-7
Purity:  99.75%
Synonyms: Δ4-abiraterone; CB-7627; abiraterone D4A metabolite
Research Areas:  

Cancer

D4-abiraterone is a major metabolite of abiraterone. D4-abiraterone is an inhibitor of CYP17A1, 3b-hydroxysteroid dehydrogenase (3βHSD) and steroid-5a-reductase (SRD5A) and also an antagonist of androgen receptor.
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Cat. No.: HY-145786
CAS No.: 2486052-18-8
Purity:  99.69%
Target:  

Cytochrome P450

Research Areas:  

Cancer

Abiraterone decanoate is a potent Abiraterone proagent. Abiraterone decanoate provide a controlled release of Abiraterone and long-acting CYP17 inhibition with intramuscular (IM) delivery .
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Cat. No.: HY-75054R
CAS No.: 154229-18-2
Synonyms: CB7630 (Standard)
Research Areas:  

Cancer

Abiraterone acetate (Standard) is the analytical standard of Abiraterone acetate. This product is intended for research and analytical applications. Abiraterone acetate (CB7630) is an oral, potent, selective, and irreversible inhibitor of CYP17A1 with antiandrogen activity. Abiraterone acetate is a proagent form of Abiraterone (CB7598).
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Cat. No.: HY-148375
CAS No.: 1993430-25-3
Purity:  98.87%
Target:  

Drug Metabolite

Research Areas:  

Others

Abiraterone sulfate is a metabolite of Abiraterone (HY-148377). Abiraterone is a potent and irreversible CYP17A1 inhibitor with antiandrogen activity .
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Cat. No.: HY-103687
CAS No.: 1940176-03-3
Purity:  99.59%
Synonyms: 3β-OH-5α-Abi
Target:  

Drug Metabolite

Research Areas:  

Cancer

Abiraterone metabolite 1 is a 5β-reduced metabolite of abiraterone. Abiraterone, a steroidal agent, inhibits CYP17A1, blocks androgen synthesis and prolongs survival in prostate cancer.
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Cat. No.: HY-137193
CAS No.: 219843-75-1
Target:  

Drug Metabolite

Research Areas:  

Cancer

5,6-Dihydroabiraterone is the metabolism of Abiraterone (HY-70013). Abiraterone is a potent and irreversible CYP17A1 inhibitor with antiandrogen activity, and shows antitumor activity in CRPC (castration-resistant prostate cancer) .
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Cat. No.: HY-148376
CAS No.: 2378463-76-2
Target:  

Drug Metabolite

Research Areas:  

Cancer

Abiraterone N-oxide is a metabolite of Abiraterone (HY-148377). Abiraterone is a potent and irreversible CYP17A1 inhibitor with antiandrogen activity .
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Cat. No.: HY-148377
CAS No.: 1993430-24-2
Target:  

Drug Metabolite

Research Areas:  

Cancer

Abiraterone sulfate N-oxide is a carboxylic acid. Abiraterone sulfate N-oxide also is a major metabolite of Abiraterone (HY-70013). Abiraterone sulfate N-oxide can be used for the research of prostate cancer .
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Cat. No.: HY-137389
CAS No.: 154229-20-6
Target:  

Drug Metabolite

Research Areas:  

Cancer

Anhydro abiraterone is a degradation product of Abiraterone acetate (HY-75054). Abiraterone acetate (CB7630) is an oral, potent, selective, and irreversible inhibitor of CYP17A1 with antiandrogen activity .
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Cat. No.: HY-75054S
CAS No.: 2122245-63-8
Synonyms: CB7630-d4
Abiraterone acetate-d4 is the deuterium labeled Abiraterone acetate. Abiraterone acetate (CB7630) is an oral, potent, selective, and irreversible inhibitor of CYP17A1 with antiandrogen activity. Abiraterone acetate is a proagent form of Abiraterone (CB7598).
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Cat. No.: HY-75054S1
CAS No.: 2122245-10-5
Synonyms: CB7630-d3
Abiraterone acetate-d3 (CB7630-d3) is deuterium labeled Abiraterone acetate. Abiraterone acetate (CB7630) is an oral, potent, selective, and irreversible inhibitor of CYP17A1 with antiandrogen activity. Abiraterone acetate is a proagent form of Abiraterone (CB7598) .
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Cat. No.: HY-70013R
CAS No.: 154229-19-3
Synonyms: CB-7598 (Standard)
Research Areas:  

Cancer

Abiraterone (Standard) is the analytical standard of Abiraterone. This product is intended for research and analytical applications. Abiraterone is a potent and irreversible CYP17A1 inhibitor with antiandrogen activity, which inhibits both the 17α-hydroxylase and 17,20-lyase activity of the cytochrome p450 enzyme CYP17 with IC50s of 2.5 nM and 15 nM, respectively.
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Cat. No.: HY-157810
Research Areas:  

Cancer

AKR1C3-IN-11 (Compound 6e) is a Aldo-keto reductase 1C3 (AKR1C3) inhibitor with an IC50 of 2.0 μM. AKR1C3-IN-11 inhibit cell proliferation in combination with abiraterone (HY-70013). AKR1C3-IN-11 can be used for the research of prostate cancer .
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Cat. No.: HY-148375R
CAS No.: 1993430-25-3
Research Areas:  

Others

Bis(2-ethylhexyl) maleate (Standard) is the analytical standard of Bis(2-ethylhexyl) maleate. This product is intended for research and analytical applications. Bis(2-ethylhexyl) maleate can enhance the water sensitivity of polyvinyl acetate (PVAc) films and improve the tackiness, adhesion, and wash resistance of polyacrylate .
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Cat. No.: HY-145786S
Abiraterone decanoate-d17 is the deuterium labeled Abiraterone decanoate (HY-145786). Abiraterone decanoate is a potent Abiraterone proagent. Abiraterone decanoate provide a controlled release of Abiraterone and long-acting CYP17 inhibition with intramuscular (IM) delivery.
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