AKR1C3-IN-11
AKR1C3-IN-11 (Compound 6e) is a Aldo-keto reductase 1C3 (AKR1C3) inhibitor with an IC50 of 2.0 μM. AKR1C3-IN-11 inhibit cell proliferation in combination with abiraterone (HY-70013). AKR1C3-IN-11 can be used for the research of prostate cancer.
For research use only. We do not sell to patients.
- Formula: C20H13F3N2O2
- Molecular Weight:370.32
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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AKR1C3 2 μM (IC50) |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| CWR22R | IC50 |
2.013 μM
Compound: 6e
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Antiproliferative activity against human 22Rv1 cells incubated for 72 hrs by SRB assay
Antiproliferative activity against human 22Rv1 cells incubated for 72 hrs by SRB assay
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[PMID: 38364714] |
Chemical Information
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Molecular Weight 370.32
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Formula C20H13F3N2O2
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SMILES
OC1=NOC2=CC=CC(NC3=CC=C(C=C3)C4=C(C=CC=C4)C(F)(F)F)=C21
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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