154229-19-3
Chemical Structure
Abiraterone
Synonym(s): CB-7598
- CAS No.: 154229-19-3
- Formula:C24H31NO
- Molecular Weight:349.51
IUPAC Name: (3S,8R,9S,10R,13S,14S)-10,13-dimethyl-17-(pyridin-3-yl)-2,3,4,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol
InChIKey: GZOSMCIZMLWJML-VJLLXTKPSA-N
SMILES: C[C@@]12C(C3=CN=CC=C3)=CC[C@]1([C@@]4(CC=C5[C@@](C)([C@]4(CC2)[H])CC[C@@H](C5)O)[H])[H]
Biological Activity: Abiraterone is a potent and irreversible CYP17A1 inhibitor with antiandrogen activity, which inhibits both the 17α-hydroxylase and 17,20-lyase activity of the cytochrome p450 enzyme CYP17 with IC50s of 2.5 nM and 15 nM, respectively.
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Abiraterone | 99.83% | Abiraterone is a potent and irreversible CYP17A1 inhibitor with antiandrogen activity, which inhibits both the 17α-hydroxylase and 17,20-lyase activity of the cytochrome p450 enzyme CYP17 with IC50s of 2.5 nM and 15 nM, respectively. | ||||||||||||||||||||
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Abiraterone (Standard) | ≥98% | Abiraterone (Standard) is the analytical standard of Abiraterone. This product is intended for research and analytical applications. Abiraterone is a potent and irreversible CYP17A1 inhibitor with antiandrogen activity, which inhibits both the 17α-hydroxylase and 17,20-lyase activity of the cytochrome p450 enzyme CYP17 with IC50s of 2.5 nM and 15 nM, respectively. | ||||||||||||||||||||
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Abiraterone-d4 | 97.7% | Abiraterone-d4 is the deuterium labeled Abiraterone. Abiraterone is a potent and irreversible CYP17A1 inhibitor with antiandrogen activity, which inhibits both the 17α-hydroxylase and 17,20-lyase activity of the cytochrome p450 enzyme CYP17 with IC50s of 2.5 nM and 15 nM, respectively. | ||||||||||||||||||||
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Similarity Score 0.84
HY-75054SAbiraterone acetate-d4 -
Similarity Score 0.84
HY-148376Abiraterone N-oxide -
Similarity Score 0.83
HY-75054Abiraterone acetate -
Similarity Score 0.81
HY-148375RAbiraterone sulfate (Standard) -
Similarity Score 0.78
HY-75054S1Abiraterone acetate-d3 -
Similarity Score 0.77
HY-137389Anhydro abiraterone -
Similarity Score 0.77
HY-103687Abiraterone metabolite 1 -
Similarity Score 0.77
HY-1371935,6-Dihydroabiraterone -
Similarity Score 0.76
HY-109619D4-abiraterone -
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