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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
25 Results for "
ala-d-
" in MedChemExpress (MCE) Product Catalog:
Products (25)
25 Results for "ala-d-" in MCE Product Catalog:
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Muramyl dipeptide (MDP) is a synthetic immunoreactive peptide, consisting of N-acetyl muramic acid attached to a short amino acid chain of L-Ala-D-isoGln. Muramyl dipeptide is an inducer of bone formation through induction of Runx2. Muramyl dipeptide directly enhances osteoblast differentiation by up-regulating Runx2 gene expression through MAPK pathways. Muramyl dipeptide is a NLRP1 agonist .
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Telavancin hydrochloride (TD-6424 hydrochloride) is a bactericidal agent that exhibits inhibitory activity against Staphylococcus aureus. Telavancin hydrochloride inhibits bacterial cell wall synthesis by binding to the lipid-linked N-acetylglucosamine-N-muramyl pentapeptide (with a D-Ala-D-Ala terminus), a peptidoglycan precursor, and blocks the transglycosylation and transpeptidation steps. Telavancin hydrochloride disrupts bacterial membrane barrier function, induces dissipation of bacterial membrane potential, and causes leakage of cytoplasmic ATP and potassium ions, with its activity restricted exclusively to bacterial membranes. Telavancin hydrochloride can be used in research on bacterial infections, central venous catheter-related bloodstream infections, and Gram-positive bacterial pneumonia .
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Cat. No.: HY-W015450
CAS No.: 923-16-0
Synonyms: D-alanyl-D-alanine; H-D-ala-D-ala-OH
Category:
Human Gut Microbiota Metabolites Natural Products Other Diseases Endogenous metabolite Disease Research Fields
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A40926 is a glycopeptide antibiotic that targets the bacterial cell wall peptidoglycan precursor D-alanyl-D-alanine (D-Ala-D-Ala). A40926 irreversibly inhibits cell wall synthesis by competitively binding to this target, and has high bactericidal activity against Gram-positive bacteria (such as Staphylococcus, Streptococcus) and Neisseria gonorrhoeae, with MIC=0.06-2 μg/mL, and is also effective against penicillin-resistant strains. A40926 blocks peptidoglycan cross-linking, destroys cell wall integrity, and causes bacterial lysis and death. A40926 has a fat-soluble fatty acid structure, which can increase serum concentrations and prolong the duration of action (e.g., the terminal half-life in rats is 61.22 h) .
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Cat. No.: HY-W250715
CAS No.: 3695-80-5
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H-Ala-d-Ala-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Cat. No.: HY-RS00553
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ALAD Human Pre-designed siRNA Set A contains three designed siRNAs for ALAD gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS17104
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Alad Mouse Pre-designed siRNA Set A contains three designed siRNAs for Alad gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS23548
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Alad Rat Pre-designed siRNA Set A contains three designed siRNAs for Alad gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-130337
CAS No.: 91032-26-7
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Teicoplanin A2-2 is a glycopeptide antibiotic. Teicoplanin A2-2 exhibits antibacterial activity, particularly against coagulase-negative staphylococci (CNS). Teicoplanin A2-2 inhibits bacterial cell wall synthesis by competitively binding to the terminal D-Ala-D-Ala peptide bonds in the cell wall synthesis process, leading to bacterial death. Teicoplanin A2-2 can be used for research into bacterial resistance mechanisms and the development of new antibiotics .
Cat. No.: HY-N0305S1
CAS No.: 187237-35-0
Synonyms: 5-ala-d2 hydrochloride; δ-Aminolevulinic acid-d2 hydrochloride; 5-Amino-4-oxopentanoic acid-d2 hydrochloride
Cat. No.: HY-W015450R
CAS No.: 923-16-0
Synonyms: D-alanyl-D-alanine (Standard); H-D-ala-D-ala-OH (Standard)
Cat. No.: HY-P3729
CAS No.: 28845-97-8
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Cat. No.: HY-P4519
CAS No.: 65882-12-4
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Cat. No.: HY-P4837
CAS No.: 220341-79-7
Cat. No.: HY-145663
CAS No.: 2243689-64-5
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HS-(CH2)3CO-L-Ala-D-Ala-L-Ala-NH-CH2-S-(CH2)5-CO-DM is a agent-linker (peptide-cleavable) conjugate for ADC. DM indicates the maytansinoid moiety .
Cat. No.: HY-P11330
Cat. No.: HY-165153
CAS No.: 62182-55-2
Synonyms: A0910 TFA; ala-D-isoGlu-Lys-D-ala-D-ala TFA
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Ala-D-γ-Glu-Lys-D-Ala-D-Ala TFA is the pentapeptide tail of the peptidoglycan precursor UDPMurNAc-l-Ala-γ-d-Glu-l-Lys(Gly)(5)-d-Ala-d-Ala .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
