30 Results for "

alpha-fetoprotein

" in MedChemExpress (MCE) Product Catalog:
Products (30)

30 Results for "alpha-fetoprotein" in MCE Product Catalog:

32
32 Publications Verification
Cat. No.: HY-10459
CAS No.: 717907-75-0
Purity:  99.68%
Synonyms: VS-6062
Target:  

FAK Pyk2

PF-562271 (VS-6062) is an orally active, ATP-competitive, reversible FAK/Pyk2 inhibitor, with an IC50 of 1.5 nM for FAK and 13 nM for Pyk2. PF-562271 induces tumor regression, and inhibits tumor growth, invasion and metastasis. PF-562271 exerts no effect on tumor necrosis, angiogenesis or apoptosis in an orthotopic mouse model of pancreatic ductal adenocarcinoma. When combined with Sunitinib (HY-10255A), PF-562271 reduces tumor vascularization, decreases serum alpha-fetoprotein levels and improves cachexia. PF-562271 can be used in research related to prostate cancer, breast cancer, pancreatic cancer, colon cancer, glioblastoma, lung cancer, pancreatic ductal adenocarcinoma and hepatocellular carcinoma .
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32
32 Publications Verification
Cat. No.: HY-10458
CAS No.: 939791-38-5
Purity:  99.17%
Synonyms: VS-6062 (besylate)
Target:  

FAK Pyk2

PF-562271 besylate (VS-6062 besylate) is an orally active, ATP-competitive, reversible FAK/Pyk2 inhibitor, with an IC50 of 1.5 nM for FAK and 13 nM for Pyk2. PF-562271 besylate induces tumor regression, and inhibits tumor growth, invasion and metastasis. PF-562271 besylate exerts no effect on tumor necrosis, angiogenesis or apoptosis in an orthotopic mouse model of pancreatic ductal adenocarcinoma. When combined with Sunitinib (HY-10255A), PF-562271 besylate reduces tumor vascularization, decreases serum alpha-fetoprotein levels and improves cachexia. PF-562271 besylate can be used in research related to prostate cancer, breast cancer, pancreatic cancer, colon cancer, glioblastoma, lung cancer, pancreatic ductal adenocarcinoma and hepatocellular carcinoma .
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30
30 Cited Publications
Cat. No.: HY-20403
CAS No.: 939791-41-0
Synonyms: VS-6062hydrochloride
Target:  

FAK Pyk2

PF-562271 hydrochloride (VS-6062 hydrochloride) is an orally active, ATP-competitive, reversible FAK/Pyk2 inhibitor, with an IC50 of 1.5 nM for FAK and 13 nM for Pyk2. PF-562271 hydrochloride induces tumor regression, and inhibits tumor growth, invasion and metastasis. PF-562271 hydrochloride exerts no effect on tumor necrosis, angiogenesis or apoptosis in an orthotopic mouse model of pancreatic ductal adenocarcinoma. When combined with Sunitinib (HY-10255A), PF-562271 hydrochloride reduces tumor vascularization, decreases serum alpha-fetoprotein levels and improves cachexia. PF-562271 hydrochloride can be used in research related to prostate cancer, breast cancer, pancreatic cancer, colon cancer, glioblastoma, lung cancer, pancreatic ductal adenocarcinoma and hepatocellular carcinoma .
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3
3 Cited Publications
Cat. No.: HY-P7463
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: AFP; alpha-Fetoglobulin; Prev. HPAFP; Fetoglobulin; alpha-fetoprotein; AFPD; alpha-1-fetoprotein; alpha fetoprotein; FETA
Species:  
Source:  
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Cat. No.: HY-160042
Research Areas:  

Cancer

AFP aptamer sodium is an aptamer that specifically targets the liver cancer biomarker alpha-fetoprotein (AFP). AFP aptamer sodium can be used as a recognition molecule for AFP, with a linear detection range of 12.5-800 ng/mL .
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Cat. No.: HY-P83929
Synonyms: alpha-fetoprotein; FETA; HPAFP

Host:  

Mouse

Application:  

WB, ELISA

Reactivity:  

Human

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Cat. No.: HY-P7464
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: AFP; alpha-Fetoglobulin; Prev. HPAFP; Fetoglobulin; alpha-fetoprotein; AFPD; alpha-1-fetoprotein; alpha fetoprotein; FETA
Species:  
Source:  
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Cat. No.: HY-P700651
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: AFP; alpha-Fetoglobulin; Prev. HPAFP; Fetoglobulin; alpha-fetoprotein; AFPD; alpha-1-fetoprotein; alpha fetoprotein; FETA
Species:  
Source:  
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Cat. No.: HY-P700652
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: AFP; alpha-Fetoglobulin; Prev. HPAFP; Fetoglobulin; alpha-fetoprotein; AFPD; alpha-1-fetoprotein; alpha fetoprotein; FETA
Species:  
Source:  
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Cat. No.: HY-P83929A
Synonyms: alpha-fetoprotein; FETA; HPAFP

Host:  

Mouse

Application:  

WB, ELISA

Reactivity:  

Human

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Cat. No.: HY-P85793
Synonyms: alpha-fetoprotein; alpha-1-fetoprotein; alpha-fetoglobulin;

Host:  

Mouse

Application:  

WB, ICC/IF, ELISA

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P81078
Synonyms: alpha fetoprotein; alpha-fetoprotein; alpha 1 fetoprotein; alpha-1-fetoprotein; alpha-fetoglobulin; alpha fetoglobulin; alpha fetoprotein; alpha fetoprotein precursor; FETA; HPAFP; FETA_HUMAN.

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, FC

Reactivity:  

Human

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Cat. No.: HY-P86117
Synonyms: AFP; HPAFP; alpha-fetoprotein; alpha-1-fetoprotein; alpha-fetoglobulin

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, IP, ELISA

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P81077
Synonyms: alpha fetoprotein; alpha-fetoprotein; alpha 1 fetoprotein; alpha-1-fetoprotein; alpha-fetoglobulin; alpha fetoglobulin; alpha fetoprotein; alpha fetoprotein precursor; FETA; HPAFP; FETA_HUMAN.

Host:  

Mouse

Application:  

WB, ELISA, IHC-P, IHC-F, ICC/IF

Reactivity:  

Human, Rat

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Cat. No.: HY-NP228
Synonyms: AFP
Alpha fetoprotein, human (AFP) is a glycoprotein belonging to the albumin family, primarily synthesized by fetal hepatocytes and the yolk sac. It plays a significant role in immunomodulation and is crucial for maintaining immune balance during pregnancy .
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Cat. No.: HY-122324
CAS No.: 482-20-2
Synonyms: (+)-(S)-Tylophorine; DCB-3500; NSC-717335
Category:  

Apocynaceae Plants Tylophora

Target:  

Others

Tylophorine and its analogs are benzoindole alkaloids, most of which are derived from Garcinia plants. Tylophorine analogs all show potent growth inhibition against human hepatocellular carcinoma HepG2 and human nasopharyngeal carcinoma KB cell lines. Tylophorine analogs can also induce increased albumin expression and inhibit α-fetoprotein expression in HepG2 cells, and have the potential to induce HepG2 cell differentiation .
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Cat. No.: HY-P990684

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

Tacatuzumab is an anti-AFP (alpha-fetoprotein protein) human IgG1 κ monoclonal antibody . Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001).
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Cat. No.: HY-187304S
[U- 15N]-AFP is the 15N-labeled AFP. Abnormally elevated levels of alpha-fetoprotein (AFP) serve as a key indicator for the diagnosis and monitoring of primary liver cancer and tumors such as testicular and ovarian cancers. This isotope can be used in NMR studies to investigate disease mechanisms and in mass spectrometry analysis.
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Cat. No.: HY-10459A
CAS No.: 939791-39-6
Synonyms: VS-6062 mesylate
Target:  

FAK Pyk2

Research Areas:  

Neurological Disease Cancer

PF-562271 mesylate (VS-6062 mesylate) is an orally active, ATP-competitive, reversible FAK/Pyk2 inhibitor, with an IC50 of 1.5 nM for FAK and 13 nM for Pyk2. PF-562271 mesylate induces tumor regression, and inhibits tumor growth, invasion and metastasis. PF-562271 mesylate exerts no effect on tumor necrosis, angiogenesis or apoptosis in an orthotopic mouse model of pancreatic ductal adenocarcinoma. When combined with Sunitinib (HY-10255A), PF-562271 mesylate reduces tumor vascularization, decreases serum alpha-fetoprotein levels and improves cachexia. PF-562271 mesylate can be used in research related to prostate cancer, breast cancer, pancreatic cancer, colon cancer, glioblastoma, lung cancer, pancreatic ductal adenocarcinoma and hepatocellular carcinoma .
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Cat. No.: HY-P991858

Research Areas:  

Others

Anti-AFP Antibody is an antibody against human Alpha fetoprotein (AFP). Recommend Isotype Controls:?Human IgG1 kappa, Isotype Control (HY-P99001).
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