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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
8 Results for "
arcA
" in MedChemExpress (MCE) Product Catalog:
Products (8)
8 Results for "arcA" in MCE Product Catalog:
Cat. No.: HY-178672
CAS No.: 400806-46-4
Synonyms: Anti-Reverse cap analog; m2 7,3′O GpppG
Target:
ARCA (Anti-Reverse cap analog; m2 7,3'OGpppG) is a 5′-cap analog. ARCA carries a methyl group at the 3'-OH position of m7G, which ensures that the cap is ligated to the 5' end of mRNA in the correct orientation during in vitro transcription and prevents reverse ligation. ARCA enhances the translation efficiency and stability of mRNA. In human immature dendritic cells, both the translation efficiency and total protein expression of ARCA-capped mRNA are higher than those of conventional m7GpppG-capped mRNA. ARCA can be used in research related to cancer, infectious diseases and mRNA vaccines .
Cat. No.: HY-153108
Purity: 99.62%
Synonyms: arcA cap solution (100 mM)
Cat. No.: HY-145969
CAS No.: 1093268-63-3
Synonyms: 3'-O-Me-m7G(5')ppp(5')G
Research Areas:
β-S-ARCA (3'-O-Me-m7G(5')ppp(5')G) is a mRNA 7-methylguanosine (m7G) cap analog carrying a phosphorothioate (PS) moiety. β-S-ARCA binds eIF4E via electrostatic interactions between its β-sulfur atom and positively charged Arg and Lys residues in the protein binding site. β-S-ARCA prevents the decapping by Dcp2, increases the mRNA half-life, enhances cap-dependent translation, and increases protein expression in cells. β-S-ARCA has been applied in researching experimental mRNA-based anticancer vaccines .
Cat. No.: HY-145969A
Purity: 99.48%
Synonyms: 3’-O-Me-m7G(5')ppp(5')G triammonium
Research Areas:
β-S-ARCA (3'-O-Me-m7G(5')ppp(5')G) triammonium is a mRNA 7-methylguanosine (m7G) cap analog carrying a phosphorothioate (PS) moiety. β-S-ARCA triammonium binds eIF4E via electrostatic interactions between its β-sulfur atom and positively charged Arg and Lys residues in the protein binding site. β-S-ARCA triammonium prevents the decapping by Dcp2, increases the mRNA half-life, enhances cap-dependent translation, and increases protein expression in cells. β-S-ARCA triammonium has been applied in researching experimental mRNA-based anticancer vaccines .
Cat. No.: HY-178672A
Synonyms: Anti-Reverse cap analog triammonium solution (100 mM); m2 7,3′O GpppG triammonium solution (100 mM)
Target:
ARCA (triammonium) solution (100 mM) (Anti-Reverse cap analog triammonium solution (100 mM); m2 7,3'OGppp triammonium solution (100 mM)) is a 5′-cap analog. ARCA (triammonium) solution (100 mM) carries a methyl group at the 3'-OH position of m7G, which ensures that the cap is ligated to the 5' end of mRNA in the correct orientation during in vitro transcription and prevents reverse ligation. ARCA (triammonium) solution (100 mM) enhances the translation efficiency and stability of mRNA. In human immature dendritic cells, both the translation efficiency and total protein expression of ARCA (triammonium) solution (100 mM)-capped mRNA are higher than those of conventional m7GpppG-capped mRNA. ARCA (triammonium) solution (100 mM) can be used in research related to cancer, infectious diseases and mRNA vaccines .
Cat. No.: HY-P700625
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Arginine deiminase; EC:3.5.3.6; ADI; Arginine dihydrolase (AD); arcA
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
