313 Results for "

complete

" in MedChemExpress (MCE) Product Catalog:
Products (313)

313 Results for "complete" in MCE Product Catalog:

63
Cy5.5
Cy5.5
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63 Publications Verification
Art. -Nr.: HY-D0924
CAS. Nr.: 210892-23-2
Synonyms: Sulfo-Cyanine5.5
Cy5.5 is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
40
CY5
CY5
0 Images
40 Cited Publications
Art. -Nr.: HY-D0821
CAS. Nr.: 146368-11-8
Synonyms: Sulfo-Cyanine5
CY5 is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
19
CY7
CY7
0 Images
19 Cited Publications
Art. -Nr.: HY-D0825
CAS. Nr.: 943298-08-6
Synonyms: Sulfo-Cyanine7
CY7 is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
15
Complete Freund's adjuvant (CFA)
Complete Freund's adjuvant (CFA)
0 Images
15 Cited Publications
Art. -Nr.: HY-153808
CAS. Nr.: 9007-81-2
Target:  

Toll-like Receptor (TLR)

Forschungsgebiete:  

Inflammation/Immunology

Complete Freund's adjuvant (CFA) is an immunoadjuvant emulsified with antigen by its discoverer Jules T. Freund to enhance an animal's immune response to an antigen. Complete Freund's adjuvant (CFA) is also an inducer of the Th1 immune response and a ligand of TLRs. Complete Freund's adjuvant (CFA) contains heat-killed inactive tuberculosis bacilli and consists of a paraffin oil-in-water emulsion. Complete Freund's adjuvant (CFA) stimulates a strong and durable immune response and can be used to induce persistent inflammatory pain models in mice, experimental autoimmune myocarditis (EAM) models, and more. Incomplete Freund's adjuvant (IFA) (HY-153808A) is another type of Freund's Adjuvant that stimulates a weaker immune response .
9
SD-36
SD-36
0 Images
9 Cited Publications
Art. -Nr.: HY-129602
CAS. Nr.: 2429877-44-9
Reinheit:  99.73%
Target:  

PROTACs STAT Apoptosis

Forschungsgebiete:  

Cancer

SD-36 is a potent and efficacious STAT3 PROTAC degrader (Kd=~50 nM), and demonstrates high selectivity over other STAT members. SD-36 also effectively degrades mutated STAT3 proteins in cells and suppresses the transcriptional activity of STAT3 (IC50=10 nM). SD-36 exerts robust anti-tumor activity, and achieves complete and long-lasting tumor regression in mouse tumor models. SD-36 is composed of the STAT3 inhibitor SI-109, a linker, and an analog of Cereblon ligand Lenalidomide for E3 ubiquitin ligase . SD-36 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
7
Cy3 NHS ester
Cy3 NHS ester
0 Images
7 Cited Publications
Art. -Nr.: HY-112498
CAS. Nr.: 1393363-07-9
Reinheit:  98.05%
Synonyms: Cyanine3 NHS ester
Cy3 NHS ester is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
7
CY7-SE
CY7-SE
0 Images
7 Cited Publications
Art. -Nr.: HY-D0824
CAS. Nr.: 477908-53-5
Synonyms: Sulfo-Cyanine7 Succinimidyl Ester
CY7-SE is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
7
CY7-SE triethylamine
CY7-SE triethylamine
0 Images
7 Cited Publications
Art. -Nr.: HY-D0824A
Synonyms: Sulfo-Cyanine7 Succinimidyl Ester triethylamine
CY7-SE triethylamine is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
5
GSK-2881078
GSK-2881078
0 Images
5 Cited Publications
Art. -Nr.: HY-100186
CAS. Nr.: 1539314-06-1
Reinheit:  99.74%
Target:  

Androgen Receptor

Forschungsgebiete:  

Cardiovascular Disease Others Metabolic Disease Inflammation/Immunology Endocrinology Cancer

GSK-2881078 is an orally active and nonsteroidal selective androgen receptor modulator (SARM) which act as partial AR agonists in androgenic tissues while mainly as complete AR agonists in synthetic metabolic tissues,induces AR-mediated transcriptional activation in PC3(AR)2 cells (EC50 = 3.99 nM) and the effect can be inhibited by the non-steroidal AR antagonist Bicalutamide. GSK-2881078 can be used in research of muscle weakness and cachexia associated with both chronic and acute illness .
4
BAY-1797
BAY-1797
0 Images
4 Cited Publications
Art. -Nr.: HY-130605
CAS. Nr.: 2055602-83-8
Reinheit:  99.76%
Target:  

P2X Receptor

Forschungsgebiete:  

Neurological Disease

BAY-1797, a chemical probe, is a potent, orally active, and selective P2X4 antagonist, with an IC50 of 211 nM against human P2X4. BAY-1797 displays no or very weak activity on the other P2X ion channels. BAY-1797 shows anti-nociceptive and anti-inflammatory effects .
4
Poncirin
Poncirin
0 Images
4 Cited Publications
Art. -Nr.: HY-N2258
CAS. Nr.: 14941-08-3
Category:  

other families Flavonoids Monophenols Flavonones Phenols Plants Disease Research Fields Inflammation/Immunology

Target:  

Apoptosis

Poncirin is isolated from Poncirus trifoliata with anti-inflammory activites. Poncirin significantly reduces mechanical hyperalgesia and allodynia in Complete Freund’s Adjuvant (CFA)-induced inflammatory pain models .
4
Serum/Protein-Free Cell Freezing Medium
Serum/Protein-Free Cell Freezing Medium
0 Images
4 Cited Publications
Art. -Nr.: HY-K1012

MCE Serum/Protein-Free Cell Freezing Medium is a complete ready-to-use cryopreservation medium. It is suitable for the cryopreservation of conventional mammalian cells and serum-free cultured cells.

4
BRD5529
BRD5529
0 Images
4 Cited Publications
Art. -Nr.: HY-115497
CAS. Nr.: 1358488-78-4
Reinheit:  98.94%
Target:  

E1/E2/E3 Enzyme

Forschungsgebiete:  

Infection Inflammation/Immunology

BRD5529 is an effective dose-dependent CARD9-TRIM62 protein–protein interaction (PPI) inhibitor with an IC50 value of 8.6 μM. BRD5529 has potency and complete inhibition of CARD9 ubiquitinylation in vitro, also has favorable solubility. BRD5529 can be used for the research of inflammatory bowel disease (IBD) such as Crohn’s disease (CD) and ulcerative colitis (UC) .
4
Incomplete Freund's adjuvant (IFA)
Incomplete Freund's adjuvant (IFA)
0 Images
4 Cited Publications
Art. -Nr.: HY-153808A
Target:  

Bacterial

Forschungsgebiete:  

Inflammation/Immunology Cancer

Incomplete Freund's adjuvant (IFA) (Montanide ISA-51) is an immunoadjuvant emulsified with antigen by its discoverer Jules T. Freund. Incomplete Freund's adjuvant (IFA) does not contain inactivated tuberculosis bacilli and consists of petroleum jelly containing lanolin. Incomplete Freund's adjuvant (IFA) induces high antibody titers and long-lasting effector T cell responses with no long-term effects on collagen disease, tumors, or death. Complete Freund's adjuvant (CFA) (HY-153808) is another type of Freund's Adjuvant that stimulates a stronger immune response .
3
NS11394
NS11394
0 Images
3 Cited Publications
Art. -Nr.: HY-11048
CAS. Nr.: 951650-22-9
Reinheit:  99.77%
Target:  

GABA Receptor

Forschungsgebiete:  

Neurological Disease

NS11394 is an orally active and unique subtype-selective GABAA positive allosteric receptor (PAM), with a Ki of ~0.5 nM. NS11394 shows a selectivity profile in the order of GABAA-5 > α3 > α2 > α1-containing receptors. NS11394 has anxiolytic and anti-inflammatory properties .
3
MI-3454
MI-3454
0 Images
3 Cited Publications
Art. -Nr.: HY-136360
CAS. Nr.: 2134169-43-8
Reinheit:  98.03%
Target:  

Epigenetic Reader Domain

Forschungsgebiete:  

Cancer

MI-3454 is an orally active, highly potent and selective menin-MLL1 interaction inhibitor with an IC50 of 0.51 nM. MI-3454 inhibits proliferation, induces differentiation and complete remission or regression of leukemia in mouse models of MLL1-rearranged or NPM1-mutated leukemia through downregulation of key genes involved in leukemogenesis .
3
Cy7.5
Cy7.5
0 Images
3 Cited Publications
Art. -Nr.: HY-D0926
CAS. Nr.: 847180-48-7
Cy7.5 is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
2
Bersacapavir
Bersacapavir
0 Images
2 Cited Publications
Art. -Nr.: HY-109168
CAS. Nr.: 1638266-40-6
Reinheit:  99.24%
Synonyms: JNJ-6379; JNJ-56136379
Target:  

HBV DNA/RNA Synthesis

Forschungsgebiete:  

Infection

Bersacapavir (JNJ-6379) is an HBV capsid assembly modulator. Bersacapavir exerts a dual mechanism of action against both early and late stages of HBV infection by forming complete genome-free empty capsids and inhibiting de novo synthesis of cccDNA. Bersacapavir inhibits HBV replication. Bersacapavir can be used in the research of hepatitis B .
2
AP-18
AP-18
0 Images
2 Cited Publications
Art. -Nr.: HY-W014421
CAS. Nr.: 55224-94-7
Target:  

TRP Channel

Forschungsgebiete:  

Neurological Disease

AP-18, a potent and selective TRPA1 inhibitor, blocks activation of TRPA1 by 50 μM Cinnamaldehyde with an IC50 of 3.1 μM and 4.5 μM for human and mouse TRPA1, respectively. AP-18 reverses complete Freund's adjuvant (CFA)-induced mechanical hyperalgesia in mice. AP-18 attenuated 30 μM AITC-induced Yo-Pro uptake in a concentration-dependent manner, with an IC50 of 10.3 μM .
1
Dazostinag disodium
Dazostinag disodium
0 Images
1 Cited Publications
Art. -Nr.: HY-148029
CAS. Nr.: 2553413-93-5
Reinheit:  98.16%
Synonyms: TAK-676
Target:  

STING

Forschungsgebiete:  

Cancer

Dazostinag disodium (TAK-676) is an agonist of STING, triggering the activation of STING signaling pathway and type I interferons. Dazostinag disodium is also a modulator of immune system, resulting complete regressions and durable memory T-cell immunity. Dazostinag disodium promotes durable IFN-dependent antitumor immunity .
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