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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
6 Results for "
core fucosylation
" in MedChemExpress (MCE) Product Catalog:
Products (6)
6 Results for "core fucosylation" in MCE Product Catalog:
1
Cat. No.: HY-E70133
CAS No.: 37278-88-9
Synonyms: Endo F2
Target:
Research Areas:
Endo-β-N-acetylglucosaminidase F2 (Endo F2), a highly specific endoglycosidase, cleaves within the chitobiose core of asparagine-linked complex biantennary and high mannose oligosaccharides from glycoproteins and glycopeptides. Endo F2 cleaves biantennary glycans at a rate approximately 20 times greater than high mannose glycans. The activity of Endo F2 is identical on biantennary structures with and without core fucosylation. Endo F2 is not active on hybrid or tri- and tetra-antennary oligosaccharides .
Cat. No.: HY-E70029
Target:
Research Areas:
alpha-1,6-Fucosidase (LpAlfC(E274A)) (EC 3.2.1.51) cleaves branched non-reducing terminal fucose, linked α(1-6) to the core N-acetylglucosamine of N-linked oligosaccharides. alpha-1,6-Fucosidase (LpAlfC(E274A)) is useful for determining core fucosylation .
Cat. No.: HY-183243
CAS No.: 1193251-61-4
Target:
Research Areas:
5-Alkynyl-L-fucose is an analog of L-fucose (HY-W854443). 5-Alkynyl-L-fucose can form acetylated derivatives, which regulate core fucosylation of IgG antibodies in mammalian cells .
Cat. No.: HY-181989
Target:
Research Areas:
CAIF is an irreversible, selective allosteric covalent inhibitor of ucosyltransferase 8 (FUT8) with an IC50 of 5.7 μM. CAIF inhibits core fucosylation modification in cancer cells, and suppresses the invasion and migration of cancer cells. CAIF is applicable for cancer research .
Cat. No.: HY-116705G
CAS No.: 70763-62-1
Synonyms: 2-Fluorofucose (GMP)
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
