11 Results for "

cyclic depsipeptides

" in MedChemExpress (MCE) Product Catalog:
Products (11)

11 Results for "cyclic depsipeptides" in MCE Product Catalog:

Cat. No.: HY-P4669
CAS No.: 1122484-55-2
Synonyms: BPR277
Target:  

Kallikrein Elastase

Research Areas:  

Inflammation/Immunology

LM-030 (BPR277), cyclic depsipeptide, is a potent kallikrein-related peptidase 7 (KLK7) and human neutrophil elastase inhibitor with IC50 values of 1 and 10 nM. LM-030 can be used for the study of Netherton syndrome .
loading...
    loading...
Cat. No.: HY-P11337
CAS No.: 403479-63-0
Research Areas:  

Others

Scyptolin B, a cyclic depsipeptides, is a secondary metabolite. Scyptolin B can be isolated from axenic cultures of Scytonema hofmanni PCC 7110. Scyptolin B selective inhibits porcine pancreatic Elastase with an IC50 of 3.1 μg/mL .
loading...
    loading...
Cat. No.: HY-19829
CAS No.: 100940-65-6
Sandramycin ia a cyclic depsipeptide antibiotic isolated from cultured broth of a Nocardioides sp. Sandramycin is also a DNA intercalator that potently binds DNA and is an ADC cytotoxin. Sandramycin is active against Gram-positive bacteria and has potent antitumor activity .
loading...
    loading...
Cat. No.: HY-N12618
Category:  

Microorganisms Phenols

Target:  

Proteasome

Crocapeptin C is a cyclic depsipeptide that can be extrated from Melittangium boletus. Crocapeptin C exhibits potent inhibitory activity against chymotrypsin with an IC50 value of 0.5 µM .
loading...
    loading...
Cat. No.: HY-N14960
CAS No.: 227083-47-8
Clavariopsin A is a cyclic depsipeptide antibiotic. Clavariopsin A shows antifungal activity for Candida albicans IFO 0583, Candida albicans ATCC 10231, Aspergillus niger AJ117374, Aspergillus fumigatus AJ117190, Aspergillus fumigatus JCM1739 with MIC values of 8, 8, 16, 2, 4 μg/mL, respectively .
loading...
    loading...
Cat. No.: HY-130564
CAS No.: 77327-06-1
Target:  

HSV

Research Areas:  

Infection Cancer

Didemnin C is a cyclic depsipeptide. Didemnin C inhibits the proliferation of herpes simplex virus (HSV) and exhibits activity against both RNA viruses and DNA viruses. Didemnin C is cytotoxic to cancer cells. Didemnin C can be used in studies related to herpes simplex virus type 2 infection and cancer .
loading...
    loading...
Cat. No.: HY-N14961
CAS No.: 227083-48-9
Clavariopsin B is a cyclic depsipeptide antibiotic. Clavariopsin B shows antifungal activity for Candida albicans IFO 0583, Candida albicans ATCC 10231, Aspergillus niger AJ117374, Aspergillus fumigatus AJ117190, Aspergillus fumigatus JCM1739 with MIC values of 8, 8, 16, 4, 4 μg/mL, respectively .
loading...
    loading...
Cat. No.: HY-N11528
CAS No.: 491-48-5
Synonyms: 7-Noreugenitin
Target:  

Others

Eugenitol (Compound 3) is an antifungal metabolite isolated and purified from Diaporthe eucalyptorum. Eugenitol has inhibitory effect on four plant pathogenic fungi (Alternaria solani, Botrytis cinerea, Fusarium solani and Gibberella saubinettii) .
loading...
    loading...
Cat. No.: HY-P3109
CAS No.: 3200-75-7
Target:  

Peptides

Research Areas:  

Others

Sporidesmolide II is a cyclic depsipeptide originally isolated from P. chartarum.
loading...
    loading...
Cat. No.: HY-P10466
CAS No.: 2377734-91-1
KZR-8445, a cyclic depsipeptide, is a client-selective Sec61 inhibitor. KZR-8445 binds to the fully opened Sec61 lateral gate, blocks lumenal plug domain access, stabilizes lateral gate helices, traps select signal peptides, and disrupts secretory and membrane protein biogenesis. KZR-8445 inhibits pro-inflammatory cytokine secretion in primary immune cells. KZR-8445 inhibits SARS-CoV-2 replication, virus-induced cytotoxicity, and spike protein biogenesis. KZR-8445 blocks disease progression in a mouse model of rheumatoid arthritis. KZR-8445 can be used for the researches of rheumatoid arthritis and SARS-CoV-2 infection .
loading...
    loading...
Cat. No.: HY-P10466A
KZR-8445 TFA, a cyclic depsipeptide, is a client-selective Sec61 inhibitor. KZR-8445 TFA binds to the fully opened Sec61 lateral gate, blocks lumenal plug domain access, stabilizes lateral gate helices, traps select signal peptides, and disrupts secretory and membrane protein biogenesis. KZR-8445 TFA inhibits pro-inflammatory cytokine secretion in primary immune cells. KZR-8445 TFA inhibits SARS-CoV-2 replication, virus-induced cytotoxicity, and spike protein biogenesis. KZR-8445 TFA blocks disease progression in a mouse model of rheumatoid arthritis. KZR-8445 TFA can be used for the researches of rheumatoid arthritis and SARS-CoV-2 infection .
loading...
    loading...
  • 1