12 Results for "

deiodinases

" in MedChemExpress (MCE) Product Catalog:
Products (12)

12 Results for "deiodinases" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-B0346
CAS No.: 51-52-5
Synonyms: 6-n-Propylthiouracil; 6-Propyl-2-thiouracil; PTU
Propylthiouracil (6-n-Propylthiouracil), a thioamide antithyroid agent, is an orally active thyroperoxidase and type-1 deiodinase (DIO1) inhibitor. Propylthiouracil can be used for the Graves disease and hyperthyroidism research .
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3
3 Cited Publications
Cat. No.: HY-B1664
CAS No.: 96-83-3
Research Areas:  

Endocrinology

Iopanoic acid is an inhibitor of 5'-Deiodinase and also an iodinated contrast medium.
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Cat. No.: HY-B1234
CAS No.: 5466-77-3
Synonyms: Octyl methoxycinnamate
Octinoxate (Octyl methoxycinnamate) is a thyroid hormone receptor agonist, reducing the levels of triiodothyronine (T3) and thyroxine (T4) and transcription levels of genes related to type II deiodinase (deio2) in Japanese Medaka. Octinoxate is commonly used as a safe ultraviolet (UV) filter used in the aquatic environment. Octinoxate inhibits CYP1A1 and CYP1B1 to regulate hyaluronan (HA) (HY-B0633A) metabolism in a PI3K pathway-dependent manner in human keratinocytes. Octinoxate also exhibits an anti-estrogenic and anti-androgenic effect in vitro and in vivo .
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Cat. No.: HY-N0864
CAS No.: 136849-88-2
Synonyms: Macranthoiside I
Macranthoidin B (Macranthoiside I) is an orally active triterpene saponin. Macranthoidin B inhibits epithelial-mesenchymal transition in endometriosis via the COX‑2/PGE2 pathway, and also induces tumor cell apoptosis and inhibits their proliferation by regulating metabolism and increasing ROS levels . Macranthoidin B can be used in studies related to endometriosis, colorectal cancer and hepatocellular carcinoma .
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Cat. No.: HY-147318
CAS No.: 1454662-41-9
Purity:  99.55%
Target:  

Apoptosis

Research Areas:  

Cancer

PBENZ-DBRMD is a potent iodothyronine deiodinase type 3 (DIO3) inhibitor. PBENZ-DBRMD has anti-proliferative activity and induces apoptosis. PBENZ-DBRMD can be used for cancer research .
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Cat. No.: HY-B0346R
CAS No.: 51-52-5
Synonyms: 6-n-Propylthiouracil (Standard); 6-Propyl-2-thiouracil (Standard); PTU (Standard)
Propylthiouracil (Standard) is the analytical standard of Propylthiouracil. This product is intended for research and analytical applications. Propylthiouracil (6-n-Propylthiouracil), a thioamide antithyroid agent, is an orally active thyroperoxidase and type-1 deiodinase (DIO1) inhibitor. Propylthiouracil can be used for the Graves disease and hyperthyroidism research .
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Cat. No.: HY-B1664R
CAS No.: 96-83-3
Iopanoic acid (Standard) is the analytical standard of Iopanoic acid. This product is intended for research and analytical applications. Iopanoic acid is an inhibitor of 5'-Deiodinase and also an iodinated contrast medium.
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Cat. No.: HY-B0346S
CAS No.: 1189423-94-6
Synonyms: 6-n-Propylthiouracil-d5; 6-Propyl-2-thiouracil-d5; PTU-d5
Propylthiouracil-d5 is the deuterium labeled Propylthiouracil. Propylthiouracil (6-Propyl-2-thiouracil) is a thyroperoxidase and 5'-deiodinase inhibitor.
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Cat. No.: HY-B1234S
Octinoxate-13C,d3 is the deuterium labeled Octinoxate (HY-W245806). Octinoxate (Octyl methoxycinnamate) is a thyroid hormone receptor agonist, reducing the levels of triiodothyronine (T3) and thyroxine (T4) and transcription levels of genes related to type II deiodinase (deio2) in Japanese Medaka. Octinoxate is commonly used as a safe ultraviolet (UV) filter used in the aquatic environment. Octinoxate inhibits CYP1A1 and CYP1B1 to regulate hyaluronan (HA) (HY-B0633A) metabolism in a PI3K pathway-dependent manner in human keratinocytes. Octinoxate also exhibits an anti-estrogenic and anti-androgenic effect in vitro and in vivo .
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Cat. No.: HY-W713284
CAS No.: 2734919-82-3
2-Ethylhexyl (E)-3-(4-(methoxy-d3)phenyl)acrylate is the deuterium labeled Octinoxate (HY-B1234). Octinoxate (Octyl methoxycinnamate) is a thyroid hormone receptor agonist, reducing the levels of triiodothyronine (T3) and thyroxine (T4) and transcription levels of genes related to type II deiodinase (deio2) in Japanese Medaka. Octinoxate is commonly used as a safe ultraviolet (UV) filter used in the aquatic environment. Octinoxate inhibits CYP1A1 and CYP1B1 to regulate hyaluronan (HA) (HY-B0633A) metabolism in a PI3K pathway-dependent manner in human keratinocytes. Octinoxate also exhibits an anti-estrogenic and anti-androgenic effect in vitro and in vivo .
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Cat. No.: HY-402216
CAS No.: 95-38-5
Research Areas:  

Endocrinology

N-b-Hydroxyethyl oleyl imidazoline is a selective enzyme inhibitor targeting DIO, with an IC50 of 3.9 μM against human DIO3. N-b-Hydroxyethyl oleyl imidazoline binds to the catalytic domain of deiodinase and blocks the deiodination catalytic reaction of thyroid hormone molecules. N-b-Hydroxyethyl oleyl imidazoline can be used in studies related to the functional regulation of thyroid deiodinases .
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Cat. No.: HY-182688
CAS No.: 1809339-61-4
Research Areas:  

Neurological Disease

ITYR-DBRMD is a type III deiodinase (DIO3) inhibitor. ITYR-DBRMD shows antidepressant-like activity and reduces latency to feed in mice. ITYR-DBRMD can be used for the research of depression .
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