10 Results for "

enterococcal

" in MedChemExpress (MCE) Product Catalog:
Products (10)

10 Results for "enterococcal" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-159688
CAS No.: 104145-95-1
Cefditoren is a broad-spectrum oral active cephalosporin that acts as a penicillin-binding protein (PBP) inhibitor. Cefditoren binds to specific PBPs in Gram-positive and Gram-negative bacteria, thereby inhibiting cell wall synthesis. Cefditoren also reduces serum levels of the inflammatory biomarkers IL-6 and KL-6. Cefditoren can be used in research related to acute exacerbation of chronic bronchitis, pharyngitis-tonsillitis, uncomplicated skin and skin structure infections, respiratory tract infections, acute pyelonephritis, and enterococcal endocarditis .
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Cat. No.: HY-B2091
CAS No.: 17243-38-8
Target:  

Antibiotic Bacterial

Research Areas:  

Infection

Azidocillin, a semi-synthetic Penicillin, is an orally active β-lactam antibiotic. Azidocillin bears an azide functionality and retains on-target activity within bacteria. Azidocillin can be used to research osteitis caused by dental surgery, otitis media, enterococcal septicemia and other bacterial infectious diseases . Azidocillin is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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Cat. No.: HY-P2200
CAS No.: 164802-68-0
Synonyms: BMY-29304
Target:  

HIV Antibiotic

Research Areas:  

Infection Inflammation/Immunology

Siamycin I (BMY-29304), a 21-residue tricyclic peptide, is a secondary metabolite in actinomycetes. Siamycin I is a HIV fusion inhibitor with ED50s of 0.05 to 5.7 μM for acute HIV type 1 (HIV-1) and HIV-2 infections. Siamycin I inhibits the gelatinase and gelatinase biosynthesis-activating pheromone (GBAP) signaling via the FsrC-FsrA two-component regulatory system in a noncompetitive manner. Siamycin I suppresses the expression of both fsrBDC and gelE-sprE transcripts. Siamycin I, a lasso peptide, interacts with lipid II and inhibits cell wall biosynthesis. Siamycin I, an antibiotic, has the potential for enterococcal infections research .
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Cat. No.: HY-B1894A
CAS No.: 111696-23-2
Synonyms: Ro 15-8075
Target:  

Antibiotic Bacterial

Research Areas:  

Infection Inflammation/Immunology

Cefetamet pivoxyl hydrochloride (Ro 15-8075) is an orally active cephalosporin Antibiotic and a prodrug of Cefetamet (HY-A0111). After ingestion, Cefetamet pivoxyl hydrochloride is hydrolyzed by gastrointestinal esterases to form Cefetamet. Cefetamet pivoxyl hydrochloride is primarily active against aerobic Gram-negative bacteria (such as Enterobacteriaceae, Neisseria, Haemophilus) and some Gram-positive bacteria (such as non-enterococcal streptococci). Cefetamet pivoxyl hydrochloride exhibits potent in vivo antibacterial activity against strains of Gram-positive bacteria (S. pyogenes) and Gram-negative bacteria (E. coli, K. pneumoniae, S. marcescens, P. vulgaris, P. mirabilis, H. influenzae) .
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Cat. No.: HY-B2091A
CAS No.: 35334-12-4
Target:  

Bacterial Antibiotic

Research Areas:  

Infection

Azidocillin sodium, a semi-synthetic Penicillin, is an orally active β-lactam antibiotic. Azidocillin sodium bears an azide functionality and retains on-target activity within bacteria. Azidocillin sodium can be used to research osteitis caused by dental surgery, otitis media, enterococcal septicemia and other bacterial infectious diseases . Azidocillin sodium is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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Cat. No.: HY-B1894
CAS No.: 65243-33-6
Synonyms: Ro 15-8075 free base
Target:  

Antibiotic Bacterial

Research Areas:  

Infection Inflammation/Immunology

Cefetamet pivoxyl (Ro 15-8075 free base) is an orally active cephalosporin Antibiotic and a prodrug of Cefetamet (HY-A0111). After ingestion, Cefetamet pivoxyl is hydrolyzed by gastrointestinal esterases to form Cefetamet. Cefetamet pivoxyl is primarily active against aerobic Gram-negative bacteria (such as Enterobacteriaceae, Neisseria, Haemophilus) and some Gram-positive bacteria (such as non-enterococcal streptococci). Cefetamet pivoxyl exhibits potent in vivo antibacterial activity against strains of Gram-positive bacteria (S. pyogenes) and Gram-negative bacteria (E. coli, K. pneumoniae, S. marcescens, P. vulgaris, P. mirabilis, H. influenzae) .
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Cat. No.: HY-B1894AR
CAS No.: 111696-23-2
Synonyms: Ro 15-8075 (Standard)
Cefetamet pivoxil (hydrochloride) (Standard) (Ro 15-8075 (Standard)) is the analytical standard of Cefetamet pivoxil (hydrochloride) (HY-B1894A). This product is intended for research and analytical applications. Cefetamet pivoxyl hydrochloride (Ro 15-8075) is an orally active cephalosporin Antibiotic and a prodrug of Cefetamet (HY-A0111). After ingestion, Cefetamet pivoxyl hydrochloride is hydrolyzed by gastrointestinal esterases to form Cefetamet. Cefetamet pivoxyl hydrochloride is primarily active against aerobic Gram-negative bacteria (such as Enterobacteriaceae, Neisseria, Haemophilus) and some Gram-positive bacteria (such as non-enterococcal streptococci). Cefetamet pivoxyl hydrochloride exhibits potent in vivo antibacterial activity against strains of Gram-positive bacteria (S. pyogenes) and Gram-negative bacteria (E. coli, K. pneumoniae, S. marcescens, P. vulgaris, P. mirabilis, H. influenzae) .
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Cat. No.: HY-B1894R
CAS No.: 65243-33-6
Synonyms: Ro 15-8075 free base (Standard)
Cefetamet pivoxyl (Standard) (Ro 15-8075 (free base) (Standard)) is the analytical standard of Cefetamet pivoxyl (HY-B1894). This product is intended for research and analytical applications. Cefetamet pivoxyl (Ro 15-8075 free base) is an orally active cephalosporin Antibiotic and a prodrug of Cefetamet (HY-A0111). After ingestion, Cefetamet pivoxyl is hydrolyzed by gastrointestinal esterases to form Cefetamet. Cefetamet pivoxyl is primarily active against aerobic Gram-negative bacteria (such as Enterobacteriaceae, Neisseria, Haemophilus) and some Gram-positive bacteria (such as non-enterococcal streptococci). Cefetamet pivoxyl exhibits potent in vivo antibacterial activity against strains of Gram-positive bacteria (S. pyogenes) and Gram-negative bacteria (E. coli, K. pneumoniae, S. marcescens, P. vulgaris, P. mirabilis, H. influenzae) .
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Cat. No.: HY-19128
CAS No.: 122536-20-3
Synonyms: PD-131112
Research Areas:  

Infection

CI-990 (PD-131112) is an orally active and highly selective bacterial DNA gyrase inhibitor. CI-990 is promising for research of Enterococcal infections (e.g., endocarditis, sepsis) .
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Cat. No.: HY-137527
CAS No.: 24570-39-6
Target:  

Bacterial

Research Areas:  

Infection

Ac-Lys (Ac)-D-Ala-D-Ala-OH is a synthetic dipeptide analog that mimics the terminal structure of bacterial peptidoglycan chains. Ac-Lys (Ac)-D-Ala-D-Ala-OH serves as a molecular decoy to investigate the mechanism of action of Vancomycin-class antibiotics, and also acts as an affinity chromatography ligand for purifying proteins that bind to Vancomycin. Ac-Lys (Ac)-D-Ala-D-Ala-OH reduces the activity of Vancomycin against susceptible enterococci. Ac-Lys (Ac)-D-Ala-D-Ala-OH is applicable to the research of Vancomycin-resistant enterococcal infections .
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