24570-39-6
Chemical Structure
Ac-Lys(Ac)-D-Ala-D-Ala-OH
- CAS No.: 24570-39-6
- Formula:C16H28N4O6
- Molecular Weight:372.42
IUPAC Name: N2,N6-diacetyl-L-lysyl-D-alanyl-D-alanine
InChIKey: VIHGYLJIMMKSBR-BREBYQMCSA-N
SMILES: [C@@H](C(N[C@@H](C(N[C@@H](C(O)=O)C)=O)C)=O)(CCCCNC(C)=O)NC(C)=O
Biological Activity: Ac-Lys (Ac)-D-Ala-D-Ala-OH is a synthetic dipeptide analog that mimics the terminal structure of bacterial peptidoglycan chains. Ac-Lys (Ac)-D-Ala-D-Ala-OH serves as a molecular decoy to investigate the mechanism of action of Vancomycin-class antibiotics, and also acts as an affinity chromatography ligand for purifying proteins that bind to Vancomycin. Ac-Lys (Ac)-D-Ala-D-Ala-OH reduces the activity of Vancomycin against susceptible enterococci. Ac-Lys (Ac)-D-Ala-D-Ala-OH is applicable to the research of Vancomycin-resistant enterococcal infections[1].
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Ac-Lys(Ac)-D-Ala-D-Ala-OH | Ac-Lys (Ac)-D-Ala-D-Ala-OH is a synthetic dipeptide analog that mimics the terminal structure of bacterial peptidoglycan chains. Ac-Lys (Ac)-D-Ala-D-Ala-OH serves as a molecular decoy to investigate the mechanism of action of Vancomycin-class antibiotics, and also acts as an affinity chromatography ligand for purifying proteins that bind to Vancomycin. Ac-Lys (Ac)-D-Ala-D-Ala-OH reduces the activity of Vancomycin against susceptible enterococci. Ac-Lys (Ac)-D-Ala-D-Ala-OH is applicable to the research of Vancomycin-resistant enterococcal infections. | |||||||||||||||||||||
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Keywords
