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Results for "

enterotoxins

" in MedChemExpress (MCE) Product Catalog:

10

阻害剤およびアゴニスト

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1

阻害性抗体

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天然物

製品番号 製品名 Target 研究分野 構造式
  • HY-19744
    T6167923
    10+ Cited Publications

    MyD88 Inflammation/Immunology
    T6167923 is a selective inhibitor of MyD88-dependent signaling pathways. T6167923 directly binds to Toll/IL1 receptor (TIR) domain of MyD88 and disrupts MyD88 homodimeric formation. T6167923 inhibits NF-κB driven Staphylococcus enterotoxin AP (SEAP) activity, and improves anti-inflammatory activity with IC50s of 2.7 μM, 2.9 μM, 2.66 μM and 2.66 μM for IFN-γ, IL-1β, IL-6 and TNF-α, respectively .
    T6167923
  • HY-113953

    Caspase Apoptosis Inflammation/Immunology
    Z-Asp-CH2-DCB is an irreversible broad spectrum caspase inhibitor. Z-Asp-CH2-DCB also inhibits proteases with caspase-like activity. Z-D-CH2-DCB blocks the production of IL-1β, TNF-α, IL-6, and IFN-γ in staphylococcal enterotoxin B (SEB)-stimulated peripheral blood mononuclear cells (PBMC), and reduces SEB-1-stimulated T-cell proliferation in a dose-dependent manner. Z-Asp-CH2-DCB prevents SU5416-induced septal cell apoptosis and emphysema development .
    Z-Asp-CH2-DCB
  • HY-19778
    (R)-BPO-27
    3 Publications Verification

    CFTR Autophagy Inflammation/Immunology
    (R)-BPO-27, the R enantiomer of BPO-27, is a potent, orally active and ATP-competitive CFTR inhibitor with an IC50 of 4 nM.
    (R)-BPO-27
  • HY-P5089

    Biochemical Assay Reagents Infection
    Enterotoxin STp (E. coli) is a heat-stable enterotoxin that can be used in vaccine research .
    Enterotoxin STp (E. coli)
  • HY-P5089A

    Biochemical Assay Reagents Infection
    Enterotoxin STp (E. coli) TFA is a heat-stable enterotoxin that can be used in vaccine research .
    Enterotoxin STp (E. coli) TFA
  • HY-163035

    TNF Receptor IFNAR Inflammation/Immunology
    EM-163 is a summative BB-Loop analog. EM-163 can alleviate inflammation and prevent death from toxic shock by targeting the TIR domain of MyD88. EM-163 can be used in the study of SEB poisoning (SEB: Staphylococcal enterotoxin B) .
    EM-163
  • HY-W743944

    Apoptosis Inflammation/Immunology
    Tilivalline is an enterotoxin that can be produced by Klebsiella oxytoca. Tilivalline shows cytotoxicity against carcinoma cells. Tilivalline induces epithelial apoptosis. Tilivalline causes antibiotic-associated hemorrhagic colitis (AAHC) .
    Tilivalline
  • HY-N7003

    28-​Norolean-​12-​en-​3-​one

    Bacterial Infection
    28-Demethyl-β-amyrone (28-Norolean-12-en-3-one) is one of the main triterpenes from Pistacia lentiscus var. Chia . 28-Demethyl-β-amyrone is an antitoxin and can effectively for the toxic effects of Staphylococcal enterotoxins (SEs) .
    28-Demethyl-β-amyrone
  • HY-178739

    Bacterial Infection
    Melibionic acid is a galactose derivative and a ganglioside GD1b inhibitor. Melibionic acid inhibits heat-labile enterotoxin with an IC50 of 7 mM .
    Melibionic acid
  • HY-P992091

    Mucin Cancer
    Nacolomab is an anti-human monoclonal antibody targeting MUC1/CD227. Nacolomab can be used for the research of cancer .
    Nacolomab

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