Tilivalline
Tilivalline is an enterotoxin that can be produced by Klebsiella oxytoca. Tilivalline shows cytotoxicity against carcinoma cells. Tilivalline induces epithelial apoptosis. Tilivalline causes antibiotic-associated hemorrhagic colitis (AAHC).
For research use only. We do not sell to patients.
- CAS No.: 80279-24-9
- Formula: C20H19N3O2
- Molecular Weight:333.38
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
Chemical Information
-
CAS No. 80279-24-9
-
Molecular Weight 333.38
-
Formula C20H19N3O2
-
SMILES
O=C1N2CCC[C@]2([C@@H](NC3=C1C=CC=C3O)C4=CNC5=C4C=CC=C5)[H]
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Hering NA, et al. Tilivalline- and Tilimycin-Independent Effects of Klebsiella oxytoca on Tight Junction-Mediated Intestinal Barrier Impairment. Int J Mol Sci. 2019 Nov 8;20(22):5595. [Content Brief]
[2]. von Tesmar A, et al. Biosynthesis of the Klebsiella oxytoca Pathogenicity Factor Tilivalline: Heterologous Expression, in Vitro Biosynthesis, and Inhibitor Development. ACS Chem Biol. 2018 Mar 16;13(3):812-819. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Powered by Bioz