8 Results for "

episodic

" in MedChemExpress (MCE) Product Catalog:
Products (8)

8 Results for "episodic" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-120782
CAS No.: 2097826-24-7
Purity:  99.34%
Target:  

Notch

Research Areas:  

Neurological Disease

Yhhu-3792 is a Notch activator. Yhhu-3792 enhances the self-renewal capability of neural stem cells (NSCs). Yhhu-3792 promotes the expression of Hes3 and Hes5. Yhhu-3792 increases the spatial and episodic memory abilities of mice. Yhhu-3792 can be used for the study of neurodegenerative diseases (such as Alzheimer's disease) or for neural regeneration after brain injury .
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1
1 Cited Publications
Cat. No.: HY-P9938
CAS No.: 1582205-90-0
Synonyms: AMG-334

Target:  

CGRP Receptor

Research Areas:  

Neurological Disease

Erenumab (AMG-334) is a fully human monoclonal antibody. Erenumab inhibits the calcitonin gene-related peptide (CGRP) receptor. Erenumab prevents the increase in dermal blood flow in cynomolgus monkeys. Erenumab can be used in the research of episodic migraine .
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Cat. No.: HY-P99017
CAS No.: 1644539-04-7
Synonyms: ALD-403

Target:  

CGRP Receptor

Research Areas:  

Neurological Disease

Eptinezumab (ALD-403) is a human monoclonal antibody targeting the α and β subtypes of human calcitonin gene-related peptide (CGRP). Eptinezumab binds to the CGRP ligand and blocks its binding to endogenous CGRP receptors, thereby inhibiting receptor activation. Eptinezumab can be used in research related to migraine .
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Cat. No.: HY-14788
CAS No.: 358970-97-5
Purity:  ≥99.0%
Synonyms: AVE1625
Target:  

Cannabinoid Receptor

Research Areas:  

Metabolic Disease

Drinabant (AVE1625) is an orally active CB1 receptor antagonist. Drinabant (AVE1625) inhibits the agonist-stimulated calcium signal with IC50 values of 25 nM and 10 nM for the hCB1-R and rCB1-R, respectively, and is ineffective for the hCB2-R .
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Cat. No.: HY-120782A
CAS No.: 2624336-93-0
Target:  

Notch

Research Areas:  

Neurological Disease

Yhhu-3792 hydrochloride is a Notch activator. Yhhu-3792 hydrochloride enhances the self-renewal capability of neural stem cells (NSCs). Yhhu-3792 hydrochloride promotes the expression of Hes3 and Hes5. Yhhu-3792 hydrochloride increases the spatial and episodic memory abilities of mice. Yhhu-3792 hydrochloride can be used for the study of neurodegenerative diseases (such as Alzheimer's disease) or for neural regeneration after brain injury .
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Cat. No.: HY-116488
CAS No.: 1778682-59-9
Target:  

nAChR

Research Areas:  

Neurological Disease

IND8 is a α7 nAChR activator and cognitive enhancer. IND8 mediates cognitive enhancement by activating α7 nAChR . IND8 improves spatial working memory, episodic short-term memory and spatial long-term memory in amnesic mice induced by Scopolamine (HY-N0296). IND8 improves memory function in mice with delayed natural memory decline. IND8 can be used in research related to Alzheimer's disease .
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Cat. No.: HY-184832
CAS No.: 1246751-68-7
Synonyms: Peptide 021
Target:  

Amyloid-β Tau Protein

Research Areas:  

Neurological Disease

P021 (Peptide 021) is an orally active, blood-brain barrier penetrant neurotrophic/neurogenic pentapeptide derived from the most active region of ciliary neurotrophic factor (CNTF). P021 competitively inhibits leukemia inhibitory factor (LIF) and promotes BDNF transcription. P021 targets neurogenesis and synaptic plasticity. P021 prevents neurodegeneration, Amyloid-β pathology, tau protein pathology and cognitive deficits, rescues episodic memory impairment and reduces mortality in 3xTg-AD mice. P021 is applicable to the research of Alzheimer's disease .
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Cat. No.: HY-P12136
CAS No.: 1966181-14-5
Synonyms: FE 205030
Target:  

CGRP Receptor

Research Areas:  

Neurological Disease

Fonagepant (FE 205030) is a calcitonin gene-related peptide (CGRP) receptor antagonist with an IC50 of 0.2 nM. Fonagepant selectively blocks CGRP receptor activity, inhibits CGRP-induced vasodilation, attenuates capsaicin-induced increase in skin blood flow, and blocks CGRP-induced vasodilation in isolated human mesenteric resistance arteries. Fonagepant can be used in studies related to acute migraine attacks .
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