358970-97-5
358970-97-5
Chemical Structure
Drinabant
Synonym(s): AVE1625
- CAS No.: 358970-97-5
- Formula:C23H20Cl2F2N2O2S
- Molecular Weight:497.38
IUPAC Name: N-(1-(bis(4-chlorophenyl)methyl)azetidin-3-yl)-N-(3,5-difluorophenyl)methanesulfonamide
InChIKey: IQQBRKLVEALROM-UHFFFAOYSA-N
SMILES: CS(=O)(N(C1CN(C(C2=CC=C(Cl)C=C2)C3=CC=C(Cl)C=C3)C1)C4=CC(F)=CC(F)=C4)=O
Biological Activity: Drinabant (AVE1625) is an orally active CB1 receptor antagonist. Drinabant (AVE1625) inhibits the agonist-stimulated calcium signal with IC50 values of 25 nM and 10 nM for the hCB1-R and rCB1-R, respectively, and is ineffective for the hCB2-R[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Drinabant | 99.0% | Drinabant (AVE1625) is an orally active CB1 receptor antagonist. Drinabant (AVE1625) inhibits the agonist-stimulated calcium signal with IC50 values of 25 nM and 10 nM for the hCB1-R and rCB1-R, respectively, and is ineffective for the hCB2-R. | ||||||||||||||||||||
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References
Keywords
