Cetirizine Impurity D
Cetirizine Impurity D is an impurity of Cetirizine. Cetirizine, a second-generation antihistamine, is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response.
For research use only. We do not sell to patients.
- CAS No.: 346451-15-8
- Formula: C30H28Cl2N2
- Molecular Weight:487.46
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Histamine Receptor Isoforms
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Biological Activity
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H1 Receptor |
Chemical Information
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CAS No. 346451-15-8
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Molecular Weight 487.46
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Formula C30H28Cl2N2
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SMILES
ClC1=CC=C(C(N2CCN(C(C3=CC=C(Cl)C=C3)C4=CC=CC=C4)CC2)C5=CC=CC=C5)C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Caroline M. Spencer, et al. Cetirizine. Drugs 46 (6): 1055-1080, 1993.
[2]. Shih MY, et al. Influence of cetirizine and levocetirizine on two cytokines secretion in human airway epithelial cells. Allergy Asthma Proc. 2008 Sep-Oct;29(5):480-5. [Content Brief]
[3]. Shimizu T, et al. Cetirizine, an H1-receptor antagonist, suppresses the expression of macrophage migration inhibitory factor: its potential anti-inflammatory action. Clin Exp Allergy. 2004 Jan;34(1):103-9. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)