2624336-93-0
Chemical Structure
Yhhu-3792 hydrochloride
- CAS No.: 2624336-93-0
- Formula:C24H25ClN4O2
- Molecular Weight:436.93
IUPAC Name: N2-(4-isopropylphenyl)-5-(3-methoxyphenoxy)quinazoline-2,4-diamine hydrochloride
InChIKey: WNNJMAWCEOKXEJ-UHFFFAOYSA-N
SMILES: [H]Cl.NC1=C2C(OC3=CC=CC(OC)=C3)=CC=CC2=NC(NC4=CC=C(C(C)C)C=C4)=N1
Biological Activity: Yhhu-3792 hydrochloride is a Notch activator. Yhhu-3792 hydrochloride enhances the self-renewal capability of neural stem cells (NSCs). Yhhu-3792 hydrochloride promotes the expression of Hes3 and Hes5. Yhhu-3792 hydrochloride increases the spatial and episodic memory abilities of mice. Yhhu-3792 hydrochloride can be used for the study of neurodegenerative diseases (such as Alzheimer's disease) or for neural regeneration after brain injury[1] [2].
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Yhhu-3792 hydrochloride | Yhhu-3792 hydrochloride is a Notch activator. Yhhu-3792 hydrochloride enhances the self-renewal capability of neural stem cells (NSCs). Yhhu-3792 hydrochloride promotes the expression of Hes3 and Hes5. Yhhu-3792 hydrochloride increases the spatial and episodic memory abilities of mice. Yhhu-3792 hydrochloride can be used for the study of neurodegenerative diseases (such as Alzheimer's disease) or for neural regeneration after brain injury . | |||||||||||||||||||||
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- [1]. Lu H, et al. A Novel 2-Phenylamino-Quinazoline-Based Compound Expands the Neural Stem Cell Pool and Promotes the Hippocampal Neurogenesis and the Cognitive Ability of Adult Mice. Stem Cells. 2018 Aug;36(8):1273-1285. [Content Brief]
- [2]. Kunkanjanawan H, et al. Efficient large-scale expansion of cord blood-derived NK cells: leveraging lipopolysaccharide for enhanced NK cell production. Cytotherapy. 2025 Jun;27(6):782-789. [Content Brief]
Keywords
