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hydroxylamine

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35

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4

Biochemical Assay Reagents

11

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3

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6

Isotope-Labeled Compounds

2

Click Chemistry

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-Y0882
    Hydroxylamine hydrochloride
    1 Publications Verification

    		 Monoamine Oxidase Cardiovascular Disease
    Hydroxylamine hydrochloride is a selective Monoamine oxidase (MAO) inhibitor used for inhibiting of platelet aggregation. Hydroxylamine hydrochloride is an intermediate of nitrogen cycle in aerobic ammonium oxidizers microorganisms, such as ammonium oxidizing bacteria (AOB), ammonium oxidizing archaea (AOA) and complete ammonium oxidizing bacteria (comammox). Hydroxylamine hydrochloride impacts NO and N2O emissions by aerobic ammonium oxidizers microorganisms and inhibits nitrite oxidizing bacteria (NOB) activity .
    Hydroxylamine hydrochloride
  • HY-17365
    Octreotide acetate
    15+ Cited Publications

    SMS 201-995 acetate

    		 Somatostatin Receptor Cardiovascular Disease Inflammation/Immunology Endocrinology Cancer
    Octreotide acetate, a long-acting synthetic analog of native somatostatin, inhibits growth hormone, glucagon, and insulin more potently.
    Octreotide acetate
  • HY-125586
    β-Amanitin

    		DNA/RNA Synthesis ADC Payload Cancer
    β-Amanitin is a cyclic peptide toxin in the poisonous Amanita phalloides mushroom. β-Amanitin inhibits inhibits eukaryotic RNA polymerase II and III. β-Amanitin inhibits protein synthesis. β-Amanitin can be used as a cytotoxic component of antibody-drug conjugates (ADCs) .
    β-Amanitin
  • HY-148983
    Hydroxylamine (50% w/w in water)
    1 Publications Verification

    		 Monoamine Oxidase Bacterial GLUT Infection Metabolic Disease Inflammation/Immunology
    Hydroxylamine (50% w/w in water) is an inorganic highly reactive compound and antibacterial agent. Hydroxylamine (50% w/w in water) acutely activates the transport activity of GLUT1, inhibits Monoamine oxidase activity. Hydroxylamine (50% w/w in water) inhibits nitrite oxidizing bacteria. Hydroxylamine (50% w/w in water) activates glucose uptake. Hydroxylamine (50% w/w in water) can be used in the research of inflammatory diseases and allergies[1][2][3][4] .
    Hydroxylamine (50% w/w in water)
  • HY-13543
    Tretazicar

    CB 1954

    		 Quinone Reductase DNA Alkylator/Crosslinker Cancer
    Tretazicar (CB 1954), an antitumor proagent, is highly selective against the Walker 256 rat tumour line. Tretazicar is enzymatically activated to generate a bifunctional agent, which can form DNA-DNA interstrand cross-links. Tretazicar in rat cells involves the reduction of its 4-nitro group to a 4-hydroxylamine by the enzyme NAD(P)H:quinone oxidoreductase 1 (NQO1) .
    Tretazicar
  • HY-Y0882S1
    Hydroxylamine-d3 hydrochloride

    		Monoamine Oxidase Cardiovascular Disease
    Hydroxylamine-d3 (hydrochloride) is the deuterium labeled Hydroxyamine hydrochloride. Hydroxylamine hydrochloride is a selective Monoamine oxidase (MAO) inhibitor used for inhibiting of platelet aggregation. Hydroxylamine hydrochloride is an intermediate of nitrogen cycle in aerobic ammonium oxidizers microorganisms, such as ammonium oxidizing bacteria (AOB), ammonium oxidizing archaea (AOA) and complete ammonium oxidizing bacteria (comammox). Hydroxylamine hydrochloride impacts NO and N2O emissions by aerobic ammonium oxidizers microorganisms and inhibits nitrite oxidizing bacteria (NOB) activity .
    Hydroxylamine-d3 hydrochloride
  • HY-W000438
    N-Boc-O-tosyl hydroxylamine

    		Amino Acid Derivatives Others
    N-Boc-O-tosyl hydroxylamine is a safe and efficient nitrogen source for N-amination of aryl and alkyl amines. N-Boc-O-tosyl hydroxylamine promotes electrophilic N-amination of aryl amines and alkyl amines to generate β-Boc-protected aryl hydrazines and alkyl hydrazines .
    N-Boc-O-tosyl hydroxylamine
  • HY-P10447
    Plipastatin A1

    Fengycin IX; SNA-60-367-3

    		 Phospholipase Infection
    Plipastatin A1 is a lipopeptide with phospholipase A2 inhibitory activity. Plipastatin A1 inhibits conidial germination of Botrytis cinerea in vitro and reduces the incidence of gray mold on tomato leaves. Plipastatin A1 is applicable to research related to gray mold .
    Plipastatin A1
  • HY-Y0024
    4-Methoxyacetophenone

    		Environmental Pollutants Drug Intermediate Others
    4-Methoxyacetophenone is a versatile aromatic ketone that is widely used in the synthesis of various organic compounds. 4-Methoxyacetophenone has a pleasant aroma and can be used to create scents. 4-Methoxyacetophenone can also be used to make dyes and pigments .
    4-Methoxyacetophenone
  • HY-137155
    Dapsone hydroxylamine

    DDS-NOH

    		 Reactive Oxygen Species (ROS) Inflammation/Immunology
    Dapsone hydroxylamine (DDS-NOH) induces methemoglobinemia. Dapsone hydroxylamine inhibits catalase (CAT) activity and reactive oxygen species generation. Dapsone hydroxylamine also has anti-inflammatory activity .
    Dapsone hydroxylamine
  • HY-W012469
    O-(4-Nitrobenzyl)hydroxylamine hydrochloride

    		Biochemical Assay Reagents Others
    O-(4-Nitrobenzyl)hydroxylamine hydrochloride is a biochemical assay reagent used for the preparation of N-(4-nitrobenzyloxy)-amino acid as substrates for an unambiguous N-hydroxypeptide synthesis.
    O-(4-Nitrobenzyl)hydroxylamine hydrochloride
  • HY-P3100
    Orfamide A

    		Parasite Infection
    Orfamide A is a major metabolite of insecticidal biosurfactant in Pseudomonas sp. F6 and has aphidicidal activity. Orfamide A can be used for aphid control in organic agriculture. Orfamide A exhibits dose-dependent mortality against aphids with an LC50 value of 34.5 μg/mL .
    Orfamide A
  • HY-151786
    Fmoc-L-Lys(Pentynoyl-DIM)-OH

    		ADC Linker Others
    Fmoc-L-Lys(Pentynoyl-DIM)-OH is a click chemistry reagent containing an azide. Fmoc-L-Lys(Pentynoyl-DIM)-OH can be used as a SPPS building block for the “helping hand” strategy for purification of highly insoluble peptides. Solubilizing residues are attached to the Lys side-chains using Click-chemistry. The solubilizing tag can be removed with 1M hydrazine or hydroxylamine solution . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
    Fmoc-L-Lys(Pentynoyl-DIM)-OH
  • HY-147384
    CXL-1020

    		Calcium Channel Cardiovascular Disease
    CXL-1020 is a hydroxylamine-based nitroxyl (HNO) donor. CXL-1020 improves cardiac inotropy/lusitropy and Ca 2+ cycling in rats with abnormal relaxation. CXL-1020 induces vasorelaxation and improves cardiac function in canine models. CXL-1020 has been used to research systolic heart failure and stable heart failure .
    CXL-1020
  • HY-158104
    LPPM-8

    		ATF6 Others
    LPPM-8 is a ligand of Med25 and an inhibitor of Med25 protein-protein interactions (PPIs). LPPM-8 engages Med25 through interaction with the H2 face of its Activator Interaction Domain and stabilizes full-length protein in the cellular proteome. LPPM-8 is an orthosteric inhibitor of H2-binding transcriptional activators (such as ATF6a). LPPM-8 can be used for studying Med25 and Mediator complex biology .
    LPPM-8
  • HY-137155S
    Dapsone hydroxylamine-d4

    DDS-NOH-d4

    		 Isotope-Labeled Compounds Others
    Dapsone hydroxylamine-d4 is the deuterium labeled Dapsone hydroxylamine .
    Dapsone hydroxylamine-d4
  • HY-W722122
    N-(1-(Adamantan-1-yl)ethyl)hydroxylamine-d4

    N-(1-((3r,5r,7r)-Adamantan-1-yl)ethyl)hydroxylamine-d4

    		 Isotope-Labeled Compounds Others
    N-(1-(Adamantan-1-yl)ethyl)hydroxylamine-d4 (N-(1-((3r,5r,7r)-Adamantan-1-yl)ethyl)hydroxylamine-d4) is the deuterium labeled N-(1-(adamantan-1-yl)ethyl)hydroxylamine (HY-75864).
    N-(1-(Adamantan-1-yl)ethyl)hydroxylamine-d4
  • HY-W073314
    2,2,2-Trifluoroethoxyamine hydrochloride

    O-(2,2,2-Trifluoroethyl)hydroxylamine hydrochloride

    		 Biochemical Assay Reagents Others
    2,2,2-Trifluoroethoxyamine (O-(2,2,2-Trifluoroethyl)hydroxylamine) hydrochloride can be used as an oxime reactant for coupling reactions with reducing sugars .
    2,2,2-Trifluoroethoxyamine hydrochloride
  • HY-106429
    OT-551 free base

    		Reactive Oxygen Species (ROS) Others
    OT-551 (free base) is a lipophilic, disubstituted hydroxylamine with antioxidant properties. OT-551 can be used as an eye drop and can be converted by intraocular esterases to its active metabolite, Tempol-H (TP-H). OT-551 can be utilized in geographic atrophy and macular degeneration research .
    OT-551 free base
  • HY-156846
    O-Benzoylhydroxylamine

    		Dipeptidyl Peptidase Metabolic Disease
    O-Benzoyl hydroxylamine is a DPP-IV inhibitor with anti-diabetic effects (WO2006034435A2) .
    O-Benzoylhydroxylamine
  • HY-13543R
    Tretazicar (Standard)

    CB 1954 (Standard)

    		 DNA Alkylator/Crosslinker Reference Standards Cancer
    Tretazicar (Standard) is the analytical standard of Tretazicar. This product is intended for research and analytical applications. Tretazicar (CB 1954), an antitumor proagent, is highly selective against the Walker 256 rat tumour line. Tretazicar is enzymatically activated to generate a bifunctional agent, which can form DNA-DNA interstrand cross-links. Tretazicar in rat cells involves the reduction of its 4-nitro group to a 4-hydroxylamine by the enzyme NAD(P)H:quinone oxidoreductase 1 (NQO1) .
    Tretazicar (Standard)
  • HY-Y1860S
    Benzyloxyamine-d5

    O-Benzylhydroxylamine-d5; O-(Phenylmethyl)hydroxylamine-d5

    		 Isotope-Labeled Compounds Others
    Benzyloxyamine-d5 (O-Benzylhydroxylamine-d5) is a deuterium labeled Benzyloxyamine.
    Benzyloxyamine-d5
  • HY-W591965
    t-Boc-aminooxy-pentane-amine

    		Biochemical Assay Reagents Others
    t-Boc-Aminooxy-pentane-amine is a linker containing an aminooxy group and a primary amine. The aminooxy group can be used in bioconjugation. It reacts with an aldehyde to form an oxime bond. If a reductant is used, it will form a hydroxylamine linkage. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.
    t-Boc-aminooxy-pentane-amine
  • HY-W800649
    Aminooxy-PEG2-amine hydrochloride

    		Biochemical Assay Reagents Others
    Aminooxy-PEG2-amine hydrochloride (compound L3) is an aqueous soluble crosslinker. The aminooxy group can be used in bioconjugation. It reacts with an aldehyde to form an oxime bond, if a reductant is used, it will form a hydroxylamine linkage. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. Aminooxy compounds are very reactive and sensitive; they cannot be stored for long term .
    Aminooxy-PEG2-amine hydrochloride
  • HY-Y0882S
    Hydroxylamine-15N hydrochloride

    		Isotope-Labeled Compounds Monoamine Oxidase Cardiovascular Disease
    Hydroxylamine- 15N hydrochloride is the 15N-labeled Hydroxylamine hydrochloride (HY-Y0882). Hydroxylamine hydrochloride is a selective Monoamine oxidase (MAO) inhibitor used for inhibiting of platelet aggregation. Hydroxylamine hydrochloride is an intermediate of nitrogen cycle in aerobic ammonium oxidizers microorganisms, such as ammonium oxidizing bacteria (AOB), ammonium oxidizing archaea (AOA) and complete ammonium oxidizing bacteria (comammox). Hydroxylamine hydrochloride impacts NO and N2O emissions by aerobic ammonium oxidizers microorganisms and inhibits nitrite oxidizing bacteria (NOB) activity .
    Hydroxylamine-15N hydrochloride
  • HY-151787
    Fmoc-L-Lys(N3-Aca-DIM)-OH

    		ADC Linker Others
    Fmoc-L-Lys(N3-Aca-DIM)-OH is a click chemistry reagent containing an azide group. Used as a SPPS building-block for the “helping hand” strategy for purification of highly insoluble peptides. Solubilizing residues are attached to the Lys side-chains using Click-chemistry. The solubilizing tag can be removed with 1M hydrazine or hydroxylamine solution . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
    Fmoc-L-Lys(N3-Aca-DIM)-OH
  • HY-W011938S
    O-((Perfluorophenyl)methyl)hydroxylamine-d2 hydrochloride

    		Isotope-Labeled Compounds Others
    O-((Perfluorophenyl)methyl)hydroxylamine-d2 (hydrochloride) is the deuterium labeled O-((Perfluorophenyl)methyl)hydroxylamine hydrochloride .
    O-((Perfluorophenyl)methyl)hydroxylamine-d2 hydrochloride
  • HY-182595
    Hydroxylamine Solution, 1.5 M, pH 8.5

    		Biochemical Assay Reagents Others
    Hydroxylamine Solution, 1.5 M, pH 8.5, is composed of 1.5 M hydroxylamine hydrochloride, deionized water, etc., with a pH of 8.5. Hydroxylamine Solution, 1.5 M, pH 8.5, is mainly used to remove unstable fluorescent groups or biotin during antibody labeling.
    Hydroxylamine Solution, 1.5 M, pH 8.5
  • HY-182594
    Hydroxylamine Solution, 1.5 M, pH 8.0

    		Biochemical Assay Reagents Others
    Hydroxylamine Solution, 1.5 M, pH 8.0, is composed of 1.5 M hydroxylamine hydrochloride, deionized water, etc., with a pH of 8.0. Hydroxylamine Solution, 1.5 M, pH 8.0, is mainly used to remove unstable fluorescent groups or biotin during antibody labeling.
    Hydroxylamine Solution, 1.5 M, pH 8.0
  • HY-180497
    DBNBS

    		Biochemical Assay Reagents Others
    DBNBS is a radical spin trapper. DBNBS rapidly reacts with the Cys-34 residue in BSA to generate hydroxylamine. DBNBS spin traps the protein-centered radicals generated by porphyrin photooxidation of BSA .
    DBNBS
  • HY-N18367
    Lemairamin

    Wgx-50

    		 nAChR Interleukin Related Akt Neurological Disease Inflammation/Immunology
    Lemairamin (Wgx-50) is a hydroxylamine compound. Lemairamin can be isolated from the pericarps of the Zanthoxylum plants. Lemairamin activates α7nAChR, stimulates the expression of IL-10 and POMC. Lemairamin shows a decrease in Akt. Lemairamin attenuates DSS-induced intestinal inflammation. Lemairamin alleviates pain hypersensitivity .
    Lemairamin
  • HY-W800650
    Aminooxy-PEG1-amine

    		Biochemical Assay Reagents Others
    Aminooxy-PEG1-amine is a chemical reagent containing an aminooxy group and a primary amine. The aminooxy group is reactive with an aldehyde to form an oxime bond. If a reductant is used, it will form a hydroxylamine linkage. The amino group is reactive withactivated NHS esters, or carboxylic acid in the presence of coupling reagent EDC. Aminooxy compounds are very reactive and sensitive; they cannot be stored for long term.
    Aminooxy-PEG1-amine
  • HY-P11783
    Surfactin C2

    		Fungal Infection
    Surfactin C2 is a lipopeptide produced by Bacillus subtilis A18 with antifungal activity. Surfactin C2 acts against Heterobasidion annosum and Heterobasidion parviporum. Surfactin C2 exerts its activity mainly through membrane‑active effects to disrupt fungal cell structures and inhibit mycelial growth. Surfactin C2 can be used for the research of butt rot and root rot of conifers .
    Surfactin C2
  • HY-P2209
    Nummularine B

    Daechuine S27; N-Demethylamphibine H

    		 Parasite Phosphodiesterase (PDE) Infection
    Nummularine B (Daechuine S27; N-Demethylamphibine H) is an anti-parasite agent. Nummularine B inhibits calmodulin-dependent phosphodiesterase activity with an IC50 of 16.8 μM. Nummularine B inhibits the growth of Plasmodium and Leishmania donovani in vitro. Nummularine B inhibits the calmodulin-dependent activity of actomyosin Ca 2+-ATPase. Nummularine B is applicable to research related to malaria and visceral leishmaniasis .
    Nummularine B
  • HY-P4948
    Coumarin-Phalloidin

    		Biochemical Assay Reagents Others
    Coumarin-phalloidin is a kind of phalloidin labeled with Coumarin (HY-N0709). Coumarin-phalloidin is a new type of actin probe that can be used for triple immunofluorescence microscopic observation of the cell skeleton .
    Coumarin-Phalloidin

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