1. Metabolic Enzyme/Protease
  2. Drug Metabolite
  3. N4-Acetylsulfamethoxazole

N4-Acetylsulfamethoxazole  (Synonyms: Acetylsulfamethoxazole)

Cat. No.: HY-W013266 Purity: 99.72%
Handling Instructions Technical Support

N4-Acetylsulfamethoxazole (Acetylsulfamethoxazole) is the N4-acetylated metabolite of Sulfamethoxazole (HY-B0322).

For research use only. We do not sell to patients.

N4-Acetylsulfamethoxazole

N4-Acetylsulfamethoxazole Chemical Structure

CAS No. : 21312-10-7

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Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
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Description

N4-Acetylsulfamethoxazole (Acetylsulfamethoxazole) is the N4-acetylated metabolite of Sulfamethoxazole (HY-B0322)[1][2].

In Vitro

Sulfamethoxazole (Ro 4-2130) is a sulfonamide antibiotic with broad-spectrum antimicrobial activity[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

295.31

Formula

C12H13N3O4S

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CC(NC1=CC=C(C=C1)S(=O)(NC2=NOC(C)=C2)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (169.31 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.3863 mL 16.9314 mL 33.8627 mL
5 mM 0.6773 mL 3.3863 mL 6.7725 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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g

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(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.72%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.3863 mL 16.9314 mL 33.8627 mL 84.6568 mL
5 mM 0.6773 mL 3.3863 mL 6.7725 mL 16.9314 mL
10 mM 0.3386 mL 1.6931 mL 3.3863 mL 8.4657 mL
15 mM 0.2258 mL 1.1288 mL 2.2575 mL 5.6438 mL
20 mM 0.1693 mL 0.8466 mL 1.6931 mL 4.2328 mL
25 mM 0.1355 mL 0.6773 mL 1.3545 mL 3.3863 mL
30 mM 0.1129 mL 0.5644 mL 1.1288 mL 2.8219 mL
40 mM 0.0847 mL 0.4233 mL 0.8466 mL 2.1164 mL
50 mM 0.0677 mL 0.3386 mL 0.6773 mL 1.6931 mL
60 mM 0.0564 mL 0.2822 mL 0.5644 mL 1.4109 mL
80 mM 0.0423 mL 0.2116 mL 0.4233 mL 1.0582 mL
100 mM 0.0339 mL 0.1693 mL 0.3386 mL 0.8466 mL
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
N4-Acetylsulfamethoxazole
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