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Results for "

monovalent cation

" in MedChemExpress (MCE) Product Catalog:

9

Inhibitors & Agonists

4

Peptides

2

Natural
Products

1

Click Chemistry

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N6790
    Nonactin

    Ammonium ionophore I

    		 Oxidative Phosphorylation Potassium Channel Mitochondrial Metabolism Bacterial Influenza Virus Apoptosis Antibiotic HSP Infection Cancer
    Nonactin is a macrotetrolide antibiotic and mitochondrial uncoupler with antibacterial, insecticidal, and acaricidal activities. Nonactin acts as an ionophore for monovalent cations, including K +, and NH4 +, and it can also inhibit the surface expression of endogenous HSP60. In addition, Nonactin can induce apoptosis in β-catenin mutant tumor cells and has anti-tumor activity .
    Nonactin
  • HY-P2324
    Gramicidin A
    1 Publications Verification

    		 Bacterial HIF/HIF Prolyl-Hydroxylase Antibiotic Infection Cancer
    Gramicidin A is a peptide component of gramicidin, an antibiotic mixture originally isolated from B. brevis. Gramicidin A is a highly hydrophobic channel-forming ionophore that forms channels in model membranes that are permeable to monovalent cations. Gramicidin A induces degradation of hypoxia inducible factor 1 α (HIF-1α) .
    Gramicidin A
  • HY-111525
    Monactin

    		Oxidative Phosphorylation Bacterial Antibiotic Infection
    Monactin is a mactrotetralide antibiotic and a non-selective ionophore for monovalent cations, including potassium, sodium, and lithium. Monactin is isolated from Streptomyces and has antiproliferative activity .
    Monactin
  • HY-P3711
    SPAI-1

    		Na+/K+ ATPase Others
    SPAI-1 is a specific inhibitor for monovalent cation transporting ATPases. SPAI-1 is a peptide isolated from porcine duodenum, inhibits Na +, K +-ATPase and H +, K +-ATPase in vitro, stimulates Mg 2+-ATPase .
    SPAI-1
  • HY-P2324A
    Gramicidin A TFA

    		Antibiotic Bacterial Infection
    Gramicidin A (TFA) is a peptide component of gramicidin, an antibiotic mixture originally isolated from B. brevis. Gramicidin A (TFA) is a highly hydrophobic channel-forming ionophore that forms channels in model membranes that are permeable to monovalent cations. Gramicidin A (TFA) induces degradation of hypoxia inducible factor 1 α (HIF-1α) .
    Gramicidin A TFA
  • HY-P10228
    S-Thanatin

    		Fungal Bacterial Infection
    S-Thanatin is an insect antimicrobial peptide with potent broad-spectrum antibacterial activity. S-Thanatin can inhibit the activity of Gram-negative bacteria, Gram-positive bacteria, and fungi, without cytotoxicity. The antibacterial activity of S-Thanatin is not affected by PH value, but monovalent cations (Na +/K +) can reduce its antibacterial activity against Gram-negative bacteria in a dose-dependent manner .
    S-Thanatin
  • HY-E70953
    Pyruvate Kinase/Lactic Dehydrogenase enzymes, Rabbit

    		Pyruvate Kinase Lactate Dehydrogenase Metabolic Disease
    Pyruvate Kinase/Lactic Dehydrogenase enzymes, Rabbit catalyzes an ATP-dependent phosphorylation of glycolate to yield 2-phosphoglycolate. Pyruvate kinase requires bivalent and monovalent cations such as Mg 2+ and K + respectively for activation to occur.
    Pyruvate Kinase/Lactic Dehydrogenase enzymes, Rabbit
  • HY-E71164
    1,5-Anhydro-D-fructose dehydratase

    		Biochemical Assay Reagents Others
    1,5-Anhydro-D-fructose dehydratase (EC 4.2.1.111) catalyses one of the steps in the anhydrofructose pathway, which leads to the degradation of glycogen and starch via 1,5-Anhydro-D-fructose . Requires divalent (Ca2+ or Mg2+) or monovalent cations (Na+) for optimal activity.
    1,5-Anhydro-D-fructose dehydratase
  • HY-183268
    TRPM4-IN-4

    		TRP Channel Cancer
    TRPM4-IN-4 (Compound 118) is a selective TRPM4 inhibitor with an IC50 value of 0.339 μM against hTRPM4. TRPM4-IN-4 inhibits hTRPM4 and mTRPM4. TRPM4-IN-4 can be used for the research of colorectal cancer .
    TRPM4-IN-4

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