6 Results for "

mouse fibroblast cell lines

" in MedChemExpress (MCE) Product Catalog:
Products (6)

6 Results for "mouse fibroblast cell lines" in MCE Product Catalog:

Cat. No.: HY-176798
CAS No.: 1964516-64-0
NCI-006 is an orally active lactate dehydrogenase (LDH) inhibitor (LDHA IC50 = 0.06 μM; LDHB IC50 = 0.03 μM). NCI-006 inhibits intratumoral LDH activity, lactate production, and tumor growth in a mouse pancreatic cancer model. NCI-006 inhibits glycolysis and induces apoptosis in vitro. NCI-006 enhances the radiosensitivity of glycolytic tumor cell lines while sparing non-glycolytic/normal cells (1522, skin fibroblasts) in combination with ionizing radiation (IR). NCI-006 exhibits synergistic antitumor effects in combination with IACS-010759 (HY-112037) against colorectal and gastric cancers. NCI-006 targets glycolysis by inhibiting lactate dehydrogenase impairs tumor growth in an Ewing sarcoma model .
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Cat. No.: HY-185347
CAS No.: 2365405-51-0
Target:  

Cholinesterase (ChE)

Research Areas:  

Neurological Disease

AChE-IN-114 is a selective AChE inhibitor and shows weak inhibitory activity for BChE. AChE-IN-114 can be used for the research of alzheimer’s disease .
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Cat. No.: HY-W053641
CAS No.: 1013-96-3
Target:  

Cholinesterase (ChE)

Research Areas:  

Neurological Disease

(E)-2-Nitrocinnamic acid (Compound 1k) is an Acetylcholinesterase inhibitor. (E)-2-Nitrocinnamic acid is applicable to research related to Alzheimer's disease .
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Cat. No.: HY-184779
CAS No.: 29435-48-1
Synonyms: PHB
Research Areas:  

Others

Poly[(R)-3-hydroxybutyrate] (PHB) is a polyhydroxyalkanoate polymer with biocompatibility and processability. Poly[(R)-3-hydroxybutyrate] can be used to prepare drug delivery nanoparticles and tissue engineering scaffolds. Poly[(R)-3-hydroxybutyrate] is applicable to research related to drug delivery, tissue engineering and wound dressing materials .
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Cat. No.: HY-126443A
CAS No.: 1352296-65-1
Target:  

Fungal

Research Areas:  

Infection

Antifungal agent 173 is an orally active antifungal (fungal) agent. Antifungal agent 173 disrupts fungal cell membrane integrity, inhibits yeast-hypha transition in Candida species, and suppresses biofilms. Antifungal agent 173 prevents mouse mortality in a mouse model of systemic candidiasis and reduces tongue lesions in a mouse model of oropharyngeal candidiasis. Antifungal agent 173 is applicable to research related to candidiasis .
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Cat. No.: HY-N20700
CAS No.: 3131756-61-8
Geministatin A is a depsipeptide antibiotic. Geministatin A exhibits activity against Gram-positive bacteria. Geministatin A can be used to study bacterial infections .
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