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Results for "

p47phox

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Akt (1) Bacterial (1) Insulin Receptor (1) NADPH Oxidase (3) NF-κB (1) Parasite (1) Reactive Oxygen Species (ROS) (1) Small Interfering RNA (siRNA) (3) TGF-β Receptor (1)
By Research Areas:	Endocrinology (1) Infection (2) Inflammation/Immunology (4) Metabolic Disease (1)
Oligonucleotides:	Rat Pre-designed siRNA Sets (1) Mouse Pre-designed siRNA Sets (1) Human Pre-designed siRNA Sets (1) siRNAs (3)

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Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-145307

DATPT	Bacterial	Infection Inflammation/Immunology
DATPT is a ₁₂WLVSKF₁₇ peptide-mimetic molecule. DATPT blocks the SNX9-p47phox interaction in the endosome and suppresses reactive oxygen species and inflammatory cytokine production. DATPT with anti-inflammatory and antibacterial functions has the potential for the research of sepsis .

HY-156425A

NOX2-IN-2 diTFA	NADPH Oxidase	Inflammation/Immunology
NOX2-IN-2 diTFA (compound 33) is a potent NOX2 inhibitor targeting the p47phox-p22phox protein-protein interaction with a K_i of 0.24 μM. NOX2-IN-2 diTFA inhibits ROS production derived from NOX2 in cells .

HY-N2421

Sequoyitol 1 Publications Verification 5-O-Methyl-myo-inositol	NF-κB TGF-β Receptor Reactive Oxygen Species (ROS) Insulin Receptor Akt Parasite	Infection Metabolic Disease Endocrinology
Sequoyitol (5-O-Methyl-myo-inositol) is an orally active hypoglycemic agent and antioxidant. Sequoyitol can be isolated from herbaceous plants. Sequoyitol downregulates the expression of NF-κB and TGF-β1, reduces ROS production and malondialdehyde levels, and enhances total antioxidant capacity. Sequoyitol activates the insulin signaling pathway, including the phosphorylation of IR, IRS1 and Akt. Sequoyitol increases serum insulin levels, inhibits hepatic glucose production, and promotes cellular glucose uptake. Sequoyitol antagonizes TNFα-induced inhibition of the insulin signaling pathway, and decreases blood urea nitrogen and serum creatinine levels. Sequoyitol elicits potential peaks in the chemosensors of adult and larval Atrophaneura alcinous, and acts as an oviposition stimulant for female Atrophaneura alcinous. Sequoyitol can be used in research related to type 2 diabetes, insulin resistance, hyperglycemia, impaired glucose tolerance and diabetic nephropathy .

HY-156425

NOX2-IN-2	NADPH Oxidase	Inflammation/Immunology
NOX2-IN-2 (compound 33) is a potent NOX2 inhibitor targeting the p47phox-p22phox protein-protein interaction with a K_i of 0.24 μM. NOX2-IN-2 inhibits ROS production derived from NOX2 in cells .

HY-156424

NOX2-IN-1	NADPH Oxidase	Inflammation/Immunology
NOX2-IN-1 (compound 10) is an inhibitor of nicotinamide adenine dinucleotide phosphate oxidase isoform 2 (NOX2). NOX2-IN-1 targets the p47phox p22phox protein protein interaction with favorable binding affinities and cellular activities .

HY-RS20305

Ncf1 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Ncf1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ncf1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Ncf1 Mouse Pre-designed siRNA Set A Ncf1 Mouse Pre-designed siRNA Set A

HY-RS09077

NCF1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
NCF1 Human Pre-designed siRNA Set A contains three designed siRNAs for NCF1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

NCF1 Human Pre-designed siRNA Set A NCF1 Human Pre-designed siRNA Set A

HY-RS26813

Ncf1 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Ncf1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Ncf1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Ncf1 Rat Pre-designed siRNA Set A Ncf1 Rat Pre-designed siRNA Set A

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N2421

Sequoyitol 1 Publications Verification 5-O-Methyl-myo-inositol	Structural Classification Natural Products Classification of Application Fields Leguminosae Glycine max (L.) merr Metabolic Disease Plants Disease Research Fields Source Classification	NF-κB TGF-β Receptor Reactive Oxygen Species (ROS) Insulin Receptor Akt Parasite
Sequoyitol (5-O-Methyl-myo-inositol) is an orally active hypoglycemic agent and antioxidant. Sequoyitol can be isolated from herbaceous plants. Sequoyitol downregulates the expression of NF-κB and TGF-β1, reduces ROS production and malondialdehyde levels, and enhances total antioxidant capacity. Sequoyitol activates the insulin signaling pathway, including the phosphorylation of IR, IRS1 and Akt. Sequoyitol increases serum insulin levels, inhibits hepatic glucose production, and promotes cellular glucose uptake. Sequoyitol antagonizes TNFα-induced inhibition of the insulin signaling pathway, and decreases blood urea nitrogen and serum creatinine levels. Sequoyitol elicits potential peaks in the chemosensors of adult and larval Atrophaneura alcinous, and acts as an oviposition stimulant for female Atrophaneura alcinous. Sequoyitol can be used in research related to type 2 diabetes, insulin resistance, hyperglycemia, impaired glucose tolerance and diabetic nephropathy .

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P70290

	Neutrophil cytosol factor 1 Protein, Human (His) rHuNeutrophil cytosol factor 1/NCF1, His; NCF-1; 47 kDa autosomal chronic granulomatous disease protein/47 kDa neutrophil oxidase factor; NCF-47K; Neutrophil NADPH oxidase factor 1; Nox organizer 2; Nox-organizing protein 2/SH3 and PX domain-containing protein 1A; p47-phox	Human	E. coli
	Neutrophil cytoplasmic factor 1 (NCF1) is essential for activation of the NADPH oxidase complex, which is essential for superoxide production. It cooperates with NCF2 to form a core association in the complex, interacting with NCF4, CYBB and CYBA. Neutrophil cytosol factor 1 Protein, Human (His) is the recombinant human-derived Neutrophil cytosol factor 1 protein, expressed by E. coli , with C-6*His labeled tag.

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Host:	Rabbit (5)
Reactivity:	Human (5) Rat (4) Mouse (4)
Application:	IHC-P (4) ICC/IF (1) IP (1) WB (5)
Isotype:	IgG (5)
Conjugation:	Non-conjugated (5)
Clonality:	Monoclonal (1) Recombinant (1)
Modification:	Unmodified (1)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P82830

	NCF1 Antibody (YA2575) NCF1; NCF1A; NOXO2; SH3PXD1A; p47phox	WB, IP	Human
	NCF1 Antibody (YA2575) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to NCF1.

HY-P811106

	p47 phox Antibody Neutrophil cytosol factor 1, NCF-1, 47 kDa neutrophil oxidase factor, NCF-47K, Neutrophil NADPH oxidase factor 1, p47-phox, Ncf1	WB, IHC-P, ICC/IF	Human, Mouse, Rat
	p47 phox Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to p47 phox.

HY-P811005

	*Phospho-p47 phox* (Ser370) Antibody** Neutrophil cytosol factor 1, NCF-1, 47 kDa neutrophil oxidase factor, NCF-47K, Neutrophil NADPH oxidase factor 1, p47-phox, Ncf1	WB, IHC-P	Human, Mouse, Rat
	Phospho-p47 phox (Ser370) Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to Phospho-p47 phox (Ser370).

HY-P811075

	*Phospho-p47 phox* (Ser304) Antibody** Neutrophil cytosol factor 1, NCF-1, 47 kDa neutrophil oxidase factor, NCF-47K, Neutrophil NADPH oxidase factor 1, p47-phox, Ncf1	WB, IHC-P	Human, Mouse, Rat
	Phospho-p47 phox (Ser304) Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to Phospho-p47 phox (Ser304).

HY-P811121

	*Phospho-p47 phox* (Ser345) Antibody** Neutrophil cytosol factor 1, NCF-1, 47 kDa neutrophil oxidase factor, NCF-47K, Neutrophil NADPH oxidase factor 1, p47-phox, Ncf1	WB, IHC-P	Human, Mouse, Rat
	Phospho-p47 phox (Ser345) Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to Phospho-p47 phox (Ser345).

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Cat. No.	Product Name		Classification

HY-RS20305

Ncf1 Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Ncf1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ncf1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS09077

NCF1 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
NCF1 Human Pre-designed siRNA Set A contains three designed siRNAs for NCF1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS26813

Ncf1 Rat Pre-designed siRNA Set A		siRNAs Rat Pre-designed siRNA Sets
Ncf1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Ncf1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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