2648709-79-7
2648709-79-7
Chemical Structure
NOX2-IN-2
- CAS No.: 2648709-79-7
- Formula:C25H25N7O3
- Molecular Weight:471.51
InChIKey: KSINOUZCQBUXCJ-UHFFFAOYSA-N
SMILES: NC1=NC2=CC=C(C=C2C=C1)OCC3=CN(N=N3)CCOCCOC4=CC=C5N=C(C=CC5=C4)N
Biological Activity: NOX2-IN-2 (compound 33) is a potent NOX2 inhibitor targeting the p47phox-p22phox protein-protein interaction with a Ki of 0.24 μM. NOX2-IN-2 inhibits ROS production derived from NOX2 in cells[1].
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NOX2-IN-2 | NOX2-IN-2 (compound 33) is a potent NOX2 inhibitor targeting the p47phox-p22phox protein-protein interaction with a Ki of 0.24 μM. NOX2-IN-2 inhibits ROS production derived from NOX2 in cells. | |||||||||||||||||||||
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References
Keywords
